药物名称：头孢唑肟钠

药物别名：头孢去甲噻肟，益保世灵、去甲氨噻肟头孢菌素、安普西林、去甲酰氧甲基唑肟头孢菌素、安保速灵Cefizox，CTZ、CZX、CFX，Epocelin

英文名称：Ceftizoxime

说明：粉针剂：1g，2g；注射剂：1g，2g。

功用作用
本品为半合成的第三代头孢菌素，抗菌谱较广，与头孢噻肟相似。抗菌谱包括：链球菌属、肺炎球菌、流感嗜血杆菌、肺炎链球菌、大肠杆菌、克雷白杆菌、变形杆菌及肠细菌属等。
用于革兰阴性敏感菌所致下呼吸道感染、菌血症、有合并症的泌尿生殖系统感染、胸膜炎、腹内感染等。

用法用量
肌内注射(深部)、静脉注射或静滴：成人1g～6g/日，2～4次/日。儿童(6月以上)每日40mg～120mg/kg，2～4次/日。

注意事项
妊娠B类。过敏者禁用。过敏体质及肾功能障碍者慎用。

〖原产地英文商品名〗CEFIZOX 1g/50ml/frozen piggy bag 10bags/box
〖原产地英文药品名〗CEFTIZOXIME SODIUM/DEXTROSE, ISO-OSMOTIC
〖中文参考商品译名〗CEFIZOX 1克/50毫升/冰冻袋 10袋/盒
〖中文参考药品译名〗头孢唑肟钠/葡萄糖,ISO-OSMOTIC
〖生产厂家中文参考译名〗安斯泰来
〖生产厂家英文名〗ASTELLAS

Cefizox
Generic Name: Ceftizoxime (SEFF-tih-ZOX-eem)
Brand Name: Cefizox

Cefizox is used for:
Treating serious infections caused by certain bacteria.

Cefizox is a cephalosporin antibiotic. It works by interfering with the formation of the bacteria's cell wall so that the wall ruptures, resulting in the death of the bacteria.

Do NOT use Cefizox if:
you are allergic to any ingredient in Cefizox or any other cephalosporin antibiotic (eg, cephalexin, cefprozil)

Contact your doctor or health care provider right away if any of these apply to you.

Before using Cefizox:
Some medical conditions may interact with Cefizox. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:
if you are pregnant, planning to become pregnant, or are breast-feeding
if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
if you have allergies to medicines, foods, or other substances
if you have diarrhea, a stomach or intestinal infection, or a blood clotting problem
if you have had a severe allergic reaction (eg, a severe rash, hives, breathing difficulties, dizziness) to a penicillin antibiotic (eg, amoxicillin) or other beta-lactam antibiotic (eg, imipenem)

Some MEDICINES MAY INTERACT with Cefizox. Tell your health care provider if you are taking any other medicines, especially any of the following:
Aminoglycosides (eg, gentamicin) because side effects, such as kidney toxicity, may be increased by Cefizox

This may not be a complete list of all interactions that may occur. Ask your health care provider if Cefizox may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Cefizox:
Use Cefizox as directed by your doctor. Check the label on the medicine for exact dosing instructions.

Cefizox is usually administered as an injection at your doctor's office, hospital, or clinic.
If you are using Cefizox at home, carefully follow the injection procedures taught to you by your health care provider.
If the medicine contains particles or is discolored, or if the vial/container is cracked or damaged in any way, do not use it.
Cefizox works best when taken at the same time(s) each day.
To clear up your infection completely, continue using Cefizox for the full course of treatment even if you feel better in a few days. Do not miss any doses.
Do not reuse needles, syringes, or other materials. Dispose of properly after use. Ask your doctor, nurse, or pharmacist to explain local regulations for selecting an appropriate container and properly disposing of the container when full.
If you miss a dose of Cefizox, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Cefizox.

Important safety information:
If severe diarrhea, stomach pain/cramps, or bloody stools occur, contact your doctor at once. This could be a symptom of a serious side effect requiring immediate medical attention. Do not treat diarrhea without consulting your doctor.
Cefizox is effective only against bacteria. It is not effective for treating viral infections (eg, the common cold).
It is important to use Cefizox for the full course of treatment. Failure to do so may decrease the effectiveness of Cefizox and may increase the risk that the bacteria will no longer be sensitive to Cefizox and will not be able to be treated by this or certain other antibiotics in the future.
LAB TESTS may be performed to monitor your progress or to check for side effects. Be sure to keep all doctor and lab appointments.
PREGNANCY and BREAST-FEEDING: If you become pregnant, discuss with your doctor the benefits and risks of using Cefizox during pregnancy. Cefizox is excreted in breast milk. Do not breast-feed while taking Cefizox.

Possible side effects of Cefizox:
All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:
Fever; mild diarrhea; nausea; vomiting.

Seek medical attention right away if any of these SEVERE side effects occur:
Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); bloody stools; pain, swelling, or redness at the injection site; seizures; severe diarrhea; stomach cramps/pain; vaginal irritation or discharge; yellowing eyes and skin.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

If OVERDOSE is suspected:
Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include muscle spasms; seizures.

Proper storage of Cefizox:
Cefizox is usually handled and stored by a health care provider. If you are using Cefizox at home, store Cefizox as directed by your pharmacist or health care provider. Keep Cefizox, as well as needles and syringes, out of the reach of children and away from pets.

General information:
If you have any questions about Cefizox, please talk with your doctor, pharmacist, or other health care provider.
Cefizox is to be used only by the patient for whom it is prescribed. Do not share it with other people.
If your symptoms do not improve or if they become worse, check with your doctor.

This information is a summary only. It does not contain all information about Cefizox. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.