中文名：盐酸非那吡啶 　　 英文名：phenazopyridine hydrochloride 　　 中文化学名：2,6-二氨基-3-苯偶氮基吡啶盐酸盐 　　 化学名：2,6-Diamino-3-(phenylazo)pyridine monohydrochloride ；2,6-Pyridinediamine, 3-(phenylazo)-, monohydrochloride 分子式：C11H11N5.HCl 分子量：249.70 适应症：强效尿道止痛药，能改善和缓解由膀脉炎、前列腺炎、尿道炎、淋病性尿道炎及内窥镜检查引起的尿道及膀胱疼痛、灼热感和尿频、尿急等不适，并能使尿道局部止痛。 产品分类：化学药品/泌尿与生殖系统药 功能主治：迅速消除膀胱镜术后和拔除导尿管后剧烈的尿道疼痛。迅速消除尿 道炎、膀胱炎、前列腺炎等疾病引起的尿道疼痛和尿频尿急症状；消除因尿路感染、尿道插管、内窥镜检查和手术、损伤等引起的尿痛、尿频、尿急、烧灼感等尿路刺激症状。 药理作用：盐酸非那吡啶为偶氮化合物，口服后以原型从尿液排出，尿液中的药物可直接作用于泌尿道粘膜并发挥止痛作用。阻断感觉传导，消除膀胱感觉超敏状态。 用法用量： 成人：口服，饭后服用。一次100mg-200mg（1-2片），一日3次。连续服用本品一般不应超过2天。在治疗尿道感染时，应与抗菌药物联合给药。儿童每日服量为12毫克/kg。分数次服用或遵医嘱。 不良反应： 1.胃肠不适、头痛、皮疹 　　 2.曾报道出现贫血、中性粒细胞减少症、血小板减少症、肾结石及肾毒性反应。有报道偶尔出现肝功能异常、溶血性贫血、高铁血红蛋白血症和急性肾衰竭。 禁忌： 1.对本品成份过敏患者禁用。 　　 2.肾功能不全、肾小球肾炎、尿毒症及严重的肝炎者禁用。 ------------------------------------------------------- 【中文品名】仲丁比妥 【药效类别】催眠镇静药>巴比妥类 【通用药名】SECBUTABARBITAL 【别　　名】BUTABARBITAL, SECBUTOBARBITONE, SECUMAL 【化学名称】2,4,6(1H,3H,5H)-Pyrimidinetrione, 5-ethyl-5-(1-methylpropyl)- 莨菪碱hyoscyamine： 一种莨菪烷型生物碱。分子式C17H23NO3。又称天仙子碱。存在于许多重要中草药中，如颠茄、北洋金花和曼陀罗。无色针状晶体。熔点108.5℃，比旋光度（乙醇）。难溶于水，可溶于沸水和乙醇、氯仿。将丁二醛、甲胺和丙酮共混于碱性溶液，经长时间放置可合成莨菪酮。莨菪碱为左旋体，在溶液中易渐渐失去旋光变为消旋体，即颠茄碱，又称为阿托品。在提取过程中，植物中的大半莨菪碱也能消旋化为颠茄碱。莨菪碱是副交感神经抑制剂，药理作用似阿托品，但毒性较大，临床应用较少。莨菪碱有止痛解痉功能，对坐骨神经痛有较好疗效，有时也用于治疗癫痫、晕船等。 【原产地英文商品名】URELIEF PLUS 30tabs/bottle 【原产地英文药品名】PHENAZOPYRIDINEHCL/HYOSCYAMINE/BUTABARBITAL 【中文参考商品译名】  以下产品是不同的规格和不同的价格，购买时请以电话咨询为准 ·URELIEF PLUS 30片/瓶 ·PYRIDIUM 200毫克/片 100片/瓶(产地：Actavis Totowa LLC） ·PYRIDIUM 200毫克/片 100片/瓶 ·PYRIDIUM 100毫克/片 100片/瓶 ·非那吡啶(PYRIDIUM仿制药) 200毫克/片 30片/瓶 ·非那吡啶(PYRIDIUM仿制药) 100毫克/片 30片/瓶 【中文参考药品译名】盐酸非那吡啶/莨菪碱/仲丁比妥 【生产厂家中文参考译名】Cypress Pharmaceutical Inc 【生产厂家英文名】Cypress Pharmaceutical Inc Urelief Plus 150 mg-15 mg-0.3 mg Tab Important note HOW TO USE THIS INFORMATION: This is a summary and does NOT have all possible information about this product. This information does not assure that this product is safe, effective, or appropriate for you. This information is not individual medical advice and does not substitute for the advice of your health care professional. Always ask your health care professional for complete information about this product and your specific health needs. Monograph title PHENAZOPYRIDINE/HYOSCYAMINE/BUTABARBITAL - ORAL Phonetic pronunciation (feh-naze-oh-PEER-ih-deen/hye-oh-SYE-uh-meen/ byoo-tuh-BARB-ih-tall) Uses This medication is used to relieve symptoms caused by irritation of the urinary tract such as pain, burning, the feeling of needing to urinate urgently or frequently, and bladder spasms. This drug does not treat the cause of the urinary irritation, but it can help relieve the symptoms while other treatments take effect. This medication is a combination of three different drugs. Phenazopyridine is a dye that works as a painkiller to soothe the lining of the urinary tract. Hyoscyamine belongs to a class of drugs known as anticholinergics/antispasmodics. It works to decrease bladder spasms. Butabarbital is a sedative that helps to relieve the anxiety that can happen when you experience urinary pain and spasms. How to use Take this medication by mouth 4 times a day after meals and at bedtime or as directed by your doctor. If you are taking this medication along with antibiotics for symptoms related to a urinary tract infection, do not take it for more than 2 days without talking to your doctor.Take each dose with a full glass of water, and drink plenty of fluids while taking this drug.Inform your doctor if your condition persists or worsens. Missed dose If you miss a dose, take it as soon as you remember. If it is near the time of the next dose, skip the missed dose and resume your usual dosing schedule. Do not double the dose to catch up. Precautions Before taking phenazopyridine/hyoscyamine/butabarbital, tell your doctor or pharmacist if you are allergic to any of these drugs; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.This medication should not be used if you have certain medical conditions. Before using this medicine, consult your doctor or pharmacist if you have: kidney disease, liver disease, blood disorders (e.g., G6PD deficiency, hemolytic anemia, porphyria), glaucoma, urinary blockage problems, enlarged prostate.Before using this medication, tell your doctor or pharmacist your medical history, especially of: stomach or intestinal disorders, overactive thyroid (hyperthyroidism), heart problems (e.g., coronary artery disease, congestive heart failure, arrhythmias), high blood pressure, mental/mood disorders, history of drug abuse, severe breathing problems, certain nervous system problems (autonomic neuropathy), myasthenia gravis.This drug may make you dizzy or drowsy or cause blurred vision. Do not drive, use machinery, or do any activity that requires alertness or clear vision until you are sure you can perform such activities safely.Avoid alcoholic beverages while using this medication, since alcohol may intensify the side effects.Before having surgery, tell your doctor or dentist that you are using this medication.Phenazopyridine can dye your urine and tears orange-red. This may stain clothing and contact lenses. Do not wear contact lenses while using this medication. Urine and tears will return to normal color after the medication is stopped.This drug may increase the risk for heatstroke because it decreases sweating. Avoid becoming overheated in hot weather, saunas, and during exercise or other strenuous activity.Kidney function declines as you grow older. This medication is removed by the kidneys. Therefore, elderly people may be at greater risk for change in amount of urine or yellowing skin/eyes.This medication is not recommended for use during pregnancy. Consult your doctor for more details.This medication passes into breast milk. Consult your doctor before breast-feeding. Side effects Stomach upset, headache, dry mouth, dry skin, drowsiness, dizziness, blurred vision, decreased sweating, diarrhea, or constipation may occur. If any of these effects persist or worsen, notify your doctor or pharmacist promptly.To relieve dry mouth, suck on (sugarless) hard candy or ice chips, chew (sugarless) gum, drink water, or use a saliva substitute.Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.Tell your doctor immediately if any of these unlikely but serious side effects occur: mental/mood changes, muscle/nerve/joint pain.Tell your doctor immediately if any of these rare but very serious side effects occur: yellowing skin/eyes, dark/bloody urine, change in the amount of urine, difficulty urinating, stomach/abdominal pain, vomiting, fever, chills, easy bruising/bleeding, unusual tiredness, shortness of breath, fast/irregular heartbeat, seizures.A very serious allergic reaction to this drug is unlikely, but seek immediate medical attention if it occurs. Symptoms of a serious allergic reaction may include: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.In the US -Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345. Drug interactions Your healthcare professionals (e.g., doctor or pharmacist) may already be aware of any possible drug interactions and may be monitoring you for it. Do not start, stop or change the dosage of any medicine before checking with them first.This drug should not be used with the following medications because very serious interactions may occur: pramlintide, sodium oxybate.If you are currently using any of these medications listed above, tell your doctor or pharmacist before starting this drug.Before using this medication, tell your doctor or pharmacist of all prescription and nonprescription/herbal products you may use, especially: antidepressants (tricyclics such as amitriptyline, MAO inhibitors such as phenelzine), certain antibiotics (doxycycline, metronidazole), beta blockers (e.g., metoprolol, propranolol), "blood thinners" (e.g., warfarin), corticosteroids (e.g., prednisone), cyclosporine, estrogens, felodipine, potassium tablets/capsules, quinidine, theophyllines, valproic acid.Tell your doctor or pharmacist if you also take drugs that cause drowsiness such as: certain antihistamines (e.g., diphenhydramine), anti-seizure drugs (e.g., carbamazepine), medicines for sleep or anxiety (e.g., alprazolam, diazepam, zolpidem), muscle relaxants, narcotic pain relievers (e.g., codeine), psychiatric medicines (e.g., chlorpromazine, risperidone, trazodone).Check the labels on all your medicines (e.g., cough-and-cold products) because they may contain drowsiness-causing ingredients. Ask your pharmacist about the safe use of those products.This medication may decrease the effectiveness of combination-type birth control pills. This can result in pregnancy. You may need to use an additional form of reliable birth control while using this medication. Consult your doctor or pharmacist for details.This product can interfere with certain laboratory tests (including urine tests for kidney function, bilirubin, and sugar levels), possibly causing false test results. Home urine tests (including diabetic tests) may be affected. Make sure laboratory personnel and all your doctors know you use this drug.This document does not contain all possible interactions. Therefore, before using this product, tell your doctor or pharmacist of all the products you use. Keep a list of all your medications with you, and share the list with your doctor and pharmacist. Overdose If overdose is suspected, contact your local poison control center or emergency room immediately. US residents can call the US national poison hotline at 1-800-222-1222. Canadian residents should call their local poison control center directly. Symptoms of overdose may include headache, nausea, vomiting, blurred vision, widened pupils, hot/dry skin, fast heartbeat, severe drowsiness, change in the amount of urine, trouble breathing, seizures, and loss of consciousness. Notes Do not share this medication with others.This medication has been prescribed for your current condition only. Do not take it later for another pain-related condition of the urinary tract unless told to do so by your doctor. A different medication may be necessary in those cases. Storage Store at room temperature between 59-86 degrees F (15-30 degrees C) away from light and moisture. Do not store in the bathroom. Keep all medicines away from children and pets.Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company for more details about how to safely discard your product.