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苯磺酸贝泊司汀1.5%滴眼液(bepotastine besilate)

2011-04-25 16:42:01  作者:新特药房  来源:中国新特药网天津分站  浏览次数:233  文字大小:【】【】【
简介:制造商: Ista药厂 药理分类: 抗组胺药/肥大细胞稳定剂 活性成分(补): Bepotastine besilate 1.5%;蛇夫座溶液,含有苯扎氯。 指示(补): 由于瘙痒治疗过敏性结膜炎。 药理作用: Bepotastine是一 ...

制造商:
Ista药厂

药理分类:
抗组胺药/肥大细胞稳定剂

活性成分(补):
Bepotastine besilate 1.5%;蛇夫座溶液,含有苯扎氯。

指示(补):
由于瘙痒治疗过敏性结膜炎。

药理作用:
Bepotastine是一个局部活跃组胺H1拮抗剂,抑制肥大细胞释放组胺。其作用机制还包括嗜酸性粒细胞迁移到发炎组织的镇压。

临床试验:
两起237例进行了临床试验,以评估在眼部瘙痒缓解由于结膜炎的bepotastine疗效。在这些挑战研究结膜过敏原,bepotastine besilate 1.5%眼用溶液比为纾缓双方15分钟后剂量眼部瘙痒,眼部过敏引起的挑战,并在8小时后,车辆的有效剂量。

法律分类
接收

成人和儿童:
<2yrs:不推荐。 ≥2yrs:1,在受影响的似乎(意味着),每天两次下降。

警告/注意事项:
摘掉隐形眼镜;服药后可能会重新插入,如果眼睛不红10分钟。妊娠(Cat.C)。哺乳的母亲。


不良反应(补):
温和的味道,眼睛不适,头痛,鼻咽炎。


如何提供:
溶液,10毫升

最后更新:
12/22/2009

BEPREVE

Manufacturer:

ISTA Pharmaceuticals

Pharmacological Class:

Antihistamine/mast cell stabilizer

Active Ingredient(s):

Bepotastine besilate 1.5%; oph soln; contains benzalkonium chloride.

Indication(s):

Treatment of itching due to allergic conjunctivitis.

Pharmacology:

Bepotastine is a topically-active histamine H1 blocker that inhibits the release of histamine from mast cells. Its mechanism of action also includes the suppression of eosinophil migration into inflamed tissues.

Clinical Trials:

Two clinical trials involving 237 patients were conducted to evaluate the efficacy of bepotastine in the relief of ocular itching due to conjunctivitis. In these conjunctival allergen challenge studies, bepotastine besilate 1.5% ophthalmic solution was more effective than vehicle for relieving ocular itching induced by ocular allergen challenges, at both 15 minutes post-dose and at 8 hours post-dose.

Legal Classification:

Rx

Adults & Children:

<2yrs: not recommended. ≥2yrs: 1 drop in affected eye(s) twice daily.

Warnings/Precautions:

Remove contact lenses; may reinsert 10 minutes after dosing if eye is not red. Pregnancy (Cat.C). Nursing mothers.

Adverse Reaction(s):

Mild taste, eye irritation, headache, nasopharyngitis.

How Supplied:

Soln—10mL

责任编辑:admin


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