通用名：硝酸咪康唑
英文通用名：Miconazole Nitrate
其他名称：硝酸双氯苯咪唑, 二氯苯咪唑硝酸盐, 达克宁, 吾玫, 硝酸咪康唑胶囊, 硝酸咪康唑栓, 硝酸咪康唑阴道栓, 硝酸咪康唑乳膏, 硝酸咪康唑软膏, 硝酸咪康唑散, 硝酸咪康唑溶液, 威净, 硝酸咪康唑阴道片, 比西优, 体贝贴, 硝酸咪康唑凝胶剂, 硝酸咪康唑阴道用软胶囊, 乐蔚, 硝酸咪康唑阴道软胶囊, 乐咪
英文其他名称：Micatin, Aflorin, Albistat, Andergin, Daktar, Daktarin, Dermonistat, GYNO-DAKTARIN, Antifungal, Dermarin, Florid, Gyno-Daktar, Micotef, Brentan, Miconazole Nitrate Cream, Miconazole Nitrate Ointment, Miconazole Nitrate Powder, Miconazole Nitrate Suppositories, Miconazole Nitrate Vaginal Tablets, Miconazole Nitrate Capsules, Miconazole Nitrate Solution

功能/功效：
1.用于念珠菌属所引起的严重感染，包括腹膜炎、肺炎和尿路感染。还可用于革兰阳性菌引起的继发性感染。
2.局部给药可用于由皮肤癣菌、酵母菌及其它多种真菌引起的慢性广泛性皮肤粘膜念珠菌病、念珠菌外阴阴道炎、..
 
注意事项：
1.禁忌症 (1)对本药过敏者。(2)孕妇。(3)1岁以下儿童。
2.慎用 有心律失常史者(国外资料)。
3.药物对妊娠的影响 动物实验表明，孕妇使用本药对胎儿有毒性，应禁用。

不良反应：
1.血液 偶可发生正红细胞性贫血、白细胞和血小板减少、高脂血症(如血胆固醇和三酰甘油升高)。静脉给药可引起血栓性静脉炎。
2.胃肠道 口服及静脉给药均可发生恶心、呕吐、腹泻和食欲减退等。
3.肝脏

给药说明：
1.过敏体质者首次使用本药时，必须进行严密观察，如有过敏征兆，应立即停药。
2.本药用于治疗真菌性脑膜炎时，为达到治疗浓度，需辅以鞘内注射给药。
3.静脉滴注开始可先给予小剂量200mg

用法与用量：
成人
·常规剂量
·口服给药 一次250-500mg，一日2次。疗程视病情而定。
·静脉滴注 用于深部真菌病，常用量一日600-1800mg(10-30mg/kg)，分3次给予。具体如下：
芽生菌病：一日200-1200mg

制剂与规格：硝酸咪康唑胶囊 250mg。
硝酸咪康唑注射液 (1)10ml:100mg。(2)20ml:200mg。
贮法：避光，密闭保存。
硝酸咪康唑阴道片 100mg。
贮法：密封保存。
硝酸咪康唑散 2%。
贮法：避光，常温保存。
禁忌：(1)对本药过敏者。(2)孕妇。(3)1岁以下儿童。

【原产地英文商品名】MICONAZOLE NITRATE 2% CREAM(GENERIC FOR MONISTAT-DERM 2%) 30g/tube
【原产地英文药品名】MICONAZOLE NITRATE
【中文参考商品译名】硝酸咪康唑2%乳膏(MONISTAT-DERM 2%仿制药) 30克/管
【中文参考药品译名】硝酸咪康唑

GENERIC NAME: miconazole
BRAND NAME: Monistat; Femizol; Vagistat; M-Zole; Micatin; Lotrimin
DRUG CLASS AND MECHANISM: Miconazole is an anti-fungal medication related to fluconazole (Diflucan), ketoconazole (Nizoral), itraconazole (Sporanox), and clotrimazole (Lotrimin, Mycelex). It is used either on the skin or in the vagina for fungal infections. Miconazole was approved by the FDA in 1974.
GENERIC AVAILABLE: yes, for some formulations
PRESCRIPTION: no for most formulations; yes (Monistat-Derm)
PREPARATIONS: Vaginal suppositories: 200 mg (Monistat-3), 100 mg (Monistat-7); Vaginal cream 2% (Monistat-7; Femizol-M); Topical cream 2% (Monistat; Monistat-Derm). Vaginal suppositories: 100 mg with topical cream 2% (Monistat 7; M-Zole 7); 200 mg with topical cream 2% (Vagistat; Monistat 3; M-Zole 3); 1200 mg with topical cream 2% (Monistat 1). Ointment 2% (Tetterine); Powder 2% (Lotrimin AF); solution 2% (Fungoid Tincture); Liquid Spray 2% (Lotrimin AF); Gel 2% (Zeasorb-AF)
STORAGE: All formulations should be stored at room temperature, 15-30°C (59-86°F).
PRESCRIBED FOR: Miconazole is used to treat vaginal infections due to Candida albicans (yeast) and several fungal infections of the skin, including tinea versicolor, tinea pedis ("athlete's foot"), tinea cruris ("jock itch") and tinea corporis ("ringworm").
DOSING: Miconazole vaginal cream and suppositories are for use only in the vagina. These products are not to be taken by mouth. The vaginal suppositories are inserted, one per dose, in an applicator. Alternatively, the tube containing the vaginal cream is screwed onto the end of a special applicator tube, and the tube is then squeezed to fill the applicator. The patient then lies on her back with bent knees, inserts the applicator containing either the suppository or cream so that the tip of the applicator is high in the vagina, and then pushes the plunger in to deposit the suppository or cream into the vagina. The applicator should be washed with warm soap and water after each use.
Miconazole usually is used once daily at bedtime. The 200 mg suppositories (Monistat 3) are inserted once nightly for 3 nights. The100 mg suppositories (Monistat-7) and intravaginal cream are inserted once nightly for 7 nights. The 1200 mg formulation (Monistat 1) is applied once for one night.
For fungal skin infections, the topical cream is applied as a thin layer to cover the affected skin and surrounding area, usually twice daily. The hands should be washed before and after application.
DRUG INTERACTIONS: There are no known drug interactions with vaginal or topical miconazole.
PREGNANCY: There is very limited information on the use of miconazole during pregnancy. The physician must weigh the potential benefits against possible but unknown risks to the fetus.
NURSING MOTHERS: It is not known if miconazole is secreted in breast milk in amounts that can affect the infant.
SIDE EFFECTS: Irritation and burning have been reported by patients using topical or vaginal miconazole.