部份中文阿替洛尔处方资料（仅供参考） Tenormin (Atenolol Tablets) 治疗类别名称 心脏选择性β受体阻滞剂 阿替洛尔；atenolol 药理作用 本品是β-肾上腺素受体阻滞剂，没有拟交感神经或稳定细胞膜作用，只有微量可通过血脑屏障。本药能够有效地消除或缓解心绞痛的症状，可能与其降低心率和收缩力有关。急性心肌梗塞情况下，及早使用本品治疗可减低病者由濒临梗塞演进至真正梗塞，同时能减少心室律不齐及痛楚，而降低服用阿片类镇痛剂的需要。 适应证 高血压，心绞痛，心律不齐，心肌梗塞之急性阶段的早期调理和复原后之心肌保护。 用法与用量 高血压、心绞痛及心律不齐：50-100mg qd。 禁忌证 II度或III度房室传导阻滞及心源性休克。 不良反应 四肢冰冷，疲劳，肠胃不适，心动过缓。偶见头痛，情绪变化，心脏衰竭状况恶化。罕见睡眠不宁，脱发，血小板减少，紫癜，牛皮癣状皮肤反应，牛皮癣恶化，视力模糊，幻想，心脏传导阻滞，体位性低血压。 注意事项 心脏代偿功能不良、心力衰竭、长期呼吸道阻塞、哮喘、有过敏史病人及妊娠和哺乳妇女慎用。 ------------------------------- 产地国家：美国 原产地英文商品名: Tenormin 25mg/Tablets 100Tablets/bottle 原产地英文药品名: Atenolol 中文参考商品译名: Tenormin 25毫克/片 100片/瓶 中文参考药品译名: 阿替洛尔 生产厂家中文参考译名: 阿斯利康 生产厂家英文名: AstraZeneca ------------------------------- 产地国家：美国 原产地英文商品名: Tenormin 50mg/Tablets 100Tablets/bottle 原产地英文药品名: Atenolol 中文参考商品译名: Tenormin 50毫克/片 100片/瓶 中文参考药品译名: 阿替洛尔 生产厂家中文参考译名: 阿斯利康 生产厂家英文名: AstraZeneca ------------------------------- 产地国家：美国 原产地英文商品名: Tenormin 100mg/Tablets 100Tablets/ bottle 原产地英文药品名: Atenolol 中文参考商品译名: Tenormin 100毫克/片 100片/瓶 中文参考药品译名: 阿替洛尔 生产厂家中文参考译名: 阿斯利康 生产厂家英文名: AstraZeneca ------------------------------- 产地国家：日本 原产地英文商品名: Tenormin（テノーミン錠）25mg/Tablets 100Tablets/box 原产地英文药品名: Atenolol 中文参考商品译名: Tenormin（テノーミン錠）25毫克/片 100片/盒 中文参考药品译名: 阿替洛尔 生产厂家中文参考译名: 阿斯利康株式会社 生产厂家英文名: AstraZeneca K.K ------------------------------- 产地国家：日本 原产地英文商品名: Tenormin（テノーミン錠）50mg/Tablets 100Tablets/box 原产地英文药品名: Atenolol 中文参考商品译名: Tenormin（テノーミン錠）50毫克/片 100片/盒 中文参考药品译名: 阿替洛尔 生产厂家中文参考译名: 阿斯利康株式会社 生产厂家英文名: AstraZeneca K.K Tenormin 25 mg, 50 mg, 100 mg(Atenolol Tablets) TENORMIN Rx Hypertension  Only 4 drugs may be compared at once Remove Selected Compare Selected Generic Name and Formulations: Atenolol 25mg, 50mg, 100mg; tabs. Company: AstraZeneca Pharmaceuticals Select therapeutic use: Angina Hypertension Indications for TENORMIN: Long-term management of angina. Adult: Initially 50mg once daily. May increase after 1 week to 100mg daily; max 200mg/day. Elderly or renal impairment: may need lower dose; monitor trough BP. Coincide a dose for the end of hemodialysis. Children: Not recommended. Contraindications: Sinus bradycardia. 2nd- or 3rd-degree heart block. Overt heart failure. Cardiogenic shock. Warnings/Precautions: Bronchospastic disease. Renal dysfunction. Diabetes. Hyperthyroidism. Pheochromocytoma. Surgery. Avoid abrupt cessation. Peripheral circulatory disorders. Ischemic heart disease or failure. Pregnancy (Cat.D): not recommended. Nursing mothers. Interactions: Additive effect with catecholamine-depleting drugs, prazosin, digoxin. Conduction abnormalities, bradycardia, heart block with calcium channel blockers (esp. verapamil, diltiazem). Increased rebound hypertension with clonidine withdrawal. May block epinephrine. Pharmacological Class: Cardioselective beta-blocker. Adverse Reactions: Heart failure, bronchospasm, bradycardia, angina, MI, heart block, dizziness, fatigue, GI upset, depression, orthostatic hypotension, cold extremities. How Supplied: Tabs 25mg, 100mg—100; 50mg—100, 1000 http://www.info.pmda.go.jp/go/pack/2123011F1155_3_05/ Generic Name: atenolol (ah TEN oh lol) Brand Names: Tenormin What is atenolol? Atenolol (Tenormin) is in a group of drugs called beta-blockers. Beta-blockers affect the heart and circulation (blood flow through arteries and veins). Atenolol is used to treat angina (chest pain) and hypertension (high blood pressure). It is also used to treat or prevent heart attack. Atenolol may also be used for purposes other than those listed in this medication guide. Important information about atenolol Do not stop taking atenolol without first talking to your doctor. Stopping suddenly may make your condition worse. If you need to have any type of surgery, you may need to temporarily stop using atenolol. Be sure the surgeon knows ahead of time that you are using atenolol. Atenolol can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert. Avoid drinking alcohol, which could increase drowsiness and dizziness while you are taking atenolol. Atenolol is only part of a complete program of treatment for hypertension that may also include diet, exercise, and weight control. Follow your diet, medication, and exercise routines very closely if you are being treated for hypertension. If you are being treated for high blood pressure, keep using this medication even if you feel fine. High blood pressure often has no symptoms. You may need to use blood pressure medication for the rest of your life. Store atenolol at room temperature away from moisture and heat. What should I discuss with my healthcare provider before taking atenolol? You should not use this medication if you are allergic to atenolol, or if you have certain heart conditions such as slow heartbeats, or heart block. Before taking atenolol, tell your doctor if you have:asthma, bronchitis, emphysema;aiabetes;low blood pressure;a heart problem such as heart block, sick sinus syndrome, slow heart rate, or congestive heart failure;depression;liver or kidney disease;a thyroidisorder;myastheniagravis;pheochromocytoma; orproblems with circulation (such as Raynaud's syndrome). If you have any of these conditions, you may need a dose adjustment or special tests to safely take this medication. FDA pregnancy category D. This medication can cause harm to an unborn baby. Do not use atenolol if you are pregnant. Tell your doctor if you become pregnant during treatment. Use an effective form of birth control while you are using this medication. Atenolol can pass into breast milk and may harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby. How should I take atenolol? Take atenolol exactly as it was prescribed for you. Do not take the medication in larger amounts or for longer than recommended by your doctor. Follow the directions on your prescription label. Take this medication with a full glass of water. Take atenolol at the same time every day. Do not skip doses or stop taking atenolol without first talking to your doctor. Stopping suddenly may make your condition worse. To be sure this medication is helping your condition, your blood pressure will need to be checked on a regular basis. Do not miss any visits to your doctor. If you need to have any type of surgery, tell the surgeon that you are using atenolol. You may need to briefly stop using atenolol before having surgery. Atenolol is only part of a complete program of treatment for hypertension that may also include diet, exercise, and weight control. Follow your diet, medication, and exercise routines very closely if you are being treated for hypertension. If you are being treated for high blood pressure, keep using atenolol even if you feel fine. High blood pressure often has no symptoms. You may need to use blood pressure medication for the rest of your life. Store atenolol at room temperature away from moisture and heat. What happens if I miss a dose? Take the missed dose as soon as you remember. If your next dose is less than 8 hours away, skip the missed dose and take the medicine at the next regularly scheduled time. Do not take extra medicine to make up the missed dose. What happens if I overdose? Seek emergency medical attention if you think you have used too much of this medicine. Overdose symptoms may include uneven heartbeats, shortness of breath, bluish-colored fingernails, dizziness, weakness, fainting, or seizure (convulsions). What should I avoid while taking atenolol? Atenolol can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert. Avoid drinking alcohol, which could increase drowsiness and dizziness while you are taking atenolol. Atenolol side effects Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Call your doctor at once if you have any of these serious side effects:Slow or uneven heartbeats;feeling light-headed, fainting;feeling short of breath,even with mild exertion;swelling of your ankles or feet;nausea, stomach pain, low fever, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes);depression; orcold feeling in your hands and feet. Less serious atenolol side effects may include:decreased sex drive, impotence, or difficulty having an orgasm;sleep problems (insomnia);tired feeling; oranxiety, nervousness. Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome. See also: Atenolol side effects in more detail What other drugs will affect atenolol? Before taking atenolol, tell your doctor if you are using:allergy treatments (or if you are undergoing allergy skin-testing);amiodarone (Cordarone, Pacerone);clonidine (Catapres);digoxi(digitalis,Lanoxin);disopyramide (Norpace);guanabenz (Wytensin);an MAO inhibitor such as isocarboxazid (Marplan), tranylcypromine (Parnate), phenelzine (Nardil), or selegiline (Eldepryl, Emsam);a diabetes medication such as insulin, glyburide (Diabeta, Micronase, Glynase), glipizide (Glucotrol), chlorpropamide (Diabinese), or metformin (Glucophage);a heart medication such as nifedipine (Procardia, Adalat), reserpine (Serpasil), verapamil (Calan, Verelan, Isoptin), diltiazem (Cartia, Cardizem);medicine for asthma or other breathing disorders, such as albuterol (Ventolin, Proventil), bitolterol (Tornalate), metaproterenol (Alupent), pirbuterol (Maxair), terbutaline (Brethaire, Brethine, Bricanyl), and theophylline (Theo-Dur, Theolair); orcold medicines, stimulant medicines, or diet pills. If you are using any of these drugs, you may not be able to take atenolol, or you may need dosage adjustments or special tests during treatment. There may be other drugs not listed that can affect atenolol. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor. Where can I get more information? Your pharmacist can provide more information about atenolol. What does my medication look like? Atenolol is available with a prescription under the brand name Tenormin. Other brand or generic forms may also be available. Ask your pharmacist any questions you have about this medication, especially if it is new to you. Tenormin 25 mg - round, flat, white, uncoated Tenormin 50 mg - round, flat, white, uncoated Tenormin 100 mg - round, flat, white, uncoated Every effort has been made to ensure that the information provided is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects.