英文药名: HCG-Pregnyl(Human Chorionic Gonadotropin Vial)

中文药名: 人绒毛膜促性腺激素注射剂

生产品牌药厂家: Organon Inc.

药品名称
【别名】 类垂体促性腺激素; 普罗兰; 绒毛膜促性腺素; 绒膜激素, 绒促性素, 绒毛膜促性腺激素, 泼热尼乐
【外文名】Chorionic Gonadotrophin, HCG, Pregnyl
【适应症】

用于不孕症、黄体功能不足、功能性子宫出血、隐睾症、男性性腺功能减退症、先兆流产或习惯性流产等 如在绝经促性素之后配合使用本品，则效果较好。 主要用于促排卵，促黄体发育。在男性可促使睾丸间质细胞分泌睾酮，可用以检验睾丸间质细胞功能，与尿促性素联合长期应用，有生精作用。
【用法用量】

1.用于无排卵性不育症，于经期第１０日起，每日肌注１次５００～１０００单位，连续５日。
2.用于黄体功能不足，于经期第１５～１７日（基础体温上升３日后），每日肌注５００～１０００单位，连用５日。
3.功能性子宫出血，每日肌注３００～１５００单位，连用３～５日。
4.１０岁以下隐睾症，每次肌注５００～１０００单位；１０～１４岁，每次肌注１５００单位，每周２～３次，连用４～８周。
5.用于男性性功能减退症，１次肌注４０００单位，每周３次。
6.先兆流产或习惯性流产，每日或隔日１次肌注３０００～５０００单位，共５～１０次。
任何疑问,请遵医嘱!
【注意事项】
1.本品溶液极不稳定，而且不耐热，配成后４日之内用完宜。
2.注射需作过敏试验。
3.生殖系统有炎症疾病、激素性活动型性腺癌、无性腺（先天性或手术后）病人忌用。
4.本品不宜长期应用，以免产生抗体和抑制垂体促性腺功能。
5.如连用８周尚不见效，应即停药；若性欲早熟或亢进，也应停用。
【规格】
针剂绒促性素：每支1500单位, 2000单位, 5000单位, 10000单位

HCG / Pregnyl (Human Chorionic Gonadotrophin)

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 Product Name:   Pregnyl
 Content:   3 x 5000IU + 1amp. solvent
 Manufacturer:   Organon, Holland
 Pharmaceutical Name:   HCG / Pregnyl
 Chemical Name:   Chorionic Gonadotropin

 Product Description

Active Life: 64 hours

Drug Class: Leutenizing Hormone (LH) - Gonadotropin

Average Dose: debatable

Acne: Yes

Water Retention: Yes

High Blood Pressure: Yes

Liver Toxic: No

Aromatization: No, but it will raise testosterone levels and increased aromatization may occur.

HCG Pregnyl information and description

Pregnyl by Organon. 1,500 to 20,000 IU (International Units) per 10 cc vials. HCG is not a steroid but it is widely used in athletics today. HCG Prengyl is a natural protein hormone secreted by the human placenta and purified form the urine of pregnant women. This hormone is not a natural male hormone but mimics the natural hormone LH (Luetinising Hormone) almost identically. This LH stimulates the production of testosterone by the testis in males. Thus HCG sends the same message and results in increased testosterone production by the testis due to its effect on the leydig cells of the testis.

Additional: HCG/Pregnyl

HCG or Human chorionic gonadotropin, which is derived from the urine of pregnant women is an injectable drug available commercially in the United States as well as many other countries. Pregnyl made by Organon, and Profasi made by Serono, are FDA approved for the treatment of undescended testicles in very young boys, hypogonadism (underproduction of testosterone) and as a fertility drug used to aid in inducing ovulation in women. Among athletes HCG is used to stimulate natural testosterone production during or after a steroid cycle which has caused natural levels to be reduced. Stopping a steroid cycle abruptly, especially when endogenous androgens are absent, can cause a rapid loss in the athlete's newly acquired muscle. When HCG is used to stimulate natural production and a notably pronounced crash may be avoided. Although fakes are not very common, they do exist and should be avoided. More than one athlete has reported unpleasant side effects (fever, aches) due to an un-sterile fake so take caution. HCG is always packaged in 2 different vials,one with a powder and the other with a sterile solvent. These vials need to be mixed before injecting, and refrigerated should any be left for later use.

HCG (Human Chorionic Gonadotropin):

Pregnyl by Organon.1,500 to 5,000 (International Units) per 1ml amps. This drug is not a steroid but it is widely used in athletics today. HCG is a natural protein hormone secreted by the human placenta and purified form the urine of pregnant women. This hormone is not a natural male hormone but mimics the natural hormone LH (Luetinising Hormone) almost identically. This LH stimulates the production of testosterone by the testis in males. Thus HCG sends the same message and results in increased testosterone production by the testis due to HCG’s effect on the leydig cells of the testis. Normally this HCG is used to treat women with certain ovarian disorders and it is used to stimulate the testis of men who may be hypogonadal. Athletes use HCG to increase the body’s own natural production of testosterone which is often depressed by long term steroid use. Also when steroids are used in high dosages they can cause false signals to the hypothalamus that results in a depressed signal to the testicles. Over a period of weeks of this depressed signal the testicles ability to respond to any signal from the pituitary becomes very weak, which results in testicular atrophy. To avoid this athletes will use HCG to keep an artificial signal going to the testis and preventing testicular atrophy.

When administered, HGC raises serum testosterone very quickly. A rise in testosterone firs appears in about two hours after injecting HCG. The second peak occurs about two to four days later. HCG therapy has been found to be very effective in the prevention of testicular atrophy and to use the body’s own biochemical stimulating mechanisms to increase plasma testosterone level during training. Some steroid users find that they have some of their best strength and size gains while using HCG in conjunction with the steroids. This may wee be due to the facts that the body has high level of natural androgens as well as the artificial steroid hormones at that time. The optimal dosage for an athlete using HCG has never been established, but it is thought hat a single shot of 1000 to 2000 IU per week will get the desired results. Cycles on the HCG should be kept down to three weeks at a time with an off cycle of at least a month in between.

For example, one might use the HCG for two to three weeks in the middle of a cycle, and for two or three weeks at the end of a cycle. It has been speculated that the prolonged use of HCG could repress the body’s own production of gonadotropins permanently. This is why the short cycles are the best way to go.

The side effects from HCG use include gynecomastia, water retention, and an increase in sex drive, mood alterations, headaches, and high blood pressure. HCG raises androgen levels in males by up to 400% but it also raises estrogen levels dramatically as well. This is why it can cause a real case of gynecomastia if dosages get too elevated for that person. Another side effect seen from HCG use is morning sickness (nausea and vomiting).

There have been no cases of overdose complications with the use of HCG nor have there been any associated carcinomas, liver or renal impairment. HCG was at one point looked at to see if it could carry the AIDS virus, due to the fact that it is biologically active, but the latest word is that this could not be possible in any way. So we see how HCG be used by athletes to avoid some of the problems associated with abruptly stopping a steroid cycle.

This product is also not picked up on steroid tests, so some athletes use it to keep androgen levels high before a contest that has drug testing. HCG must be refergerated after it is mixed together, and it then has a life of about 10 weeks. It is taken intramuscularly only; this drug is often available by order of a physician if you show symptoms of hypogonadism. It is hard to find on the black market.

Description: HCG is a glycoprotein that is secreted in the urine by pregnant women. It is legally used as a fertility drug for women to helpinduce ovulation. This drug is used by male athletes to elevate natural levels of testosterone production, mostly after a steroid cycle. This drug is used to kick start your testosterone after a cycle. While on steroids for long periods of time (more than 3 - 4 weeks) your natural testosterone shuts down. A shot of this each week for 2 weeks straight will get things going again.

It should be used for no more than 2 weeks at a time because it also raises a male's natural production of estrogen (and we don't want any gyno now do we?). For that reason take some Nolvadex with it also.

HCG is always packaged in 2 different vials, one with a powder and the other with a sterile solvent. These vials need to be mixed before injecting, and refrigerated should any be left for later use.

Effective Dose: 1500-2500IU per week.

Stacking Info:

Used to come off of a steroid cycle. Take with Nolvadex to reduce side effects.

When administered, HCG raises serum testosterone very quickly. A rise in testosterone first appears about 2 hours after injecting HCG. The second peak occurs about 2 to 4 days later. HCG therapy has been found to be very effective in the prevention of testicular atrophy as well as to use the body's own biochemical stimulating mechanisms to increase plasma testosterone levels during training. Some steroid users find that they have some of their best strength and size gains while using HCG in conjunction with steroids. This may well be due to the fact that the body has a high level of natural androgens as well as the artificial steroid hormones at that time. The optimal dosage for an athlete using HCG has never been established, but it is thought that a single shot of 1000 to 2000 IU per week will get the desired results. Cycles on HCG should be kept down to around 3 weeks at a time with an off cycle of at least a month in between. For example, one might use the HCG for 2 or 3 weeks in the middle of a cycle, and for 2 or 3 weeks at the end of a cycle. It has been speculated that the prolonged use of HCG could repress the body's own production of gonadotrophins permanently. This is why short cycles are the best way to go. The side effects from HCG use include gynecomastia, water retention, increased sex drive, mood alterations, headaches, and high blood pressure. HCG raises androgen levels in males by up to 400% but it also raises estrogen levels dramatically as well, This is why it can cause gynecomastia. Other side effects seen from HCG use include "morning sickness like" symptoms (nausea and vomiting). There have been no cases of overdose complications with the use of HCG nor have there been any associated carcinomas, liver or renal impairment.

HCG was at one point looked at to see if it could cany the AIDS virus, due to the fact that it is biologically active, but the latest word is that this could not be possible in any way. HCG must be refrigerated after it is mixed together and it then has a life of about 10 weeks. It is taken intramuscularly only. This drug is often available by order of a physician if you show symptoms of hypogonadism.

HCG:Human Chorionic Gonadotropin is a drug used to jump start the body's production of testosterone after the end of a steroid cycle. It act in the body by imitating the action of LH (a hormone that regulated testosterone production).

Dose: 2500IU to 5000IU/week.

 HCG:

HCG is a glycoprotein that is secreted in the urine by pregnant women. It is legally used as a fertility drug for women to help induce ovulation. This drug is used by male athletes to elevate natural levels of testosterone production, mostly after a steroid cycle. This drug is used to kick start your testosterone after a cycle. While on steroids for long periods of time (more than 3 - 4 weeks) your natural testosterone shuts down. A shot of this each week for 2 weeks straight will get things going again. It should be used for no more than 2 weeks at a time because it also raises a male's natural production of estrogen. For that reason take some Nolvadex with it also. HCG is always packaged in 2 different vials, one with a powder and the other with a sterile solvent. These vials need to be mixed before injecting.

HCG, is not an anabolic/an-drogenic steroid but a natural protein hormone which develops in the placenta of a pregnant woman. HCG is manufac-tured from the urine of pregnant women since it is excreted in unchanged form from the blood via the woman's urine, passing through the kidneys. The commercially available HCG is sold as a dry substance and can be used both in men and women. in women injectable HCG allows for ovulation since it influences the last stages of the development of the ovum, thus stimulating ovulation. In a man HCG stimulates production of androgenic hormones (testosterone). For this reason athletes use injectable HCG to increase the testosterone production. HCG is often used in combination with anabolic/androgenic steroids during or after treatment. Since the body usually needs a certain amount of time to get its testosterone production going again, the athlete, after discontinuing steroid compounds, experiences a difficult transition phase which often goes hand in hand with a considerable loss in both strength and muscle mass. Administering HCG directly after steroid treatment helps to reduce this condition because HCG increases the testosterone production in the testes very quickly and reliably. In the event of testicular atrophy caused by mega doses and very long periods of usage, HCG also helps to quickly bring the testes back to their original condition (size). Since occasional injections of HCG during steroid intake can avoid a testicular atrophy, many athletes use HCG for two to three weeks in the middle of their steroid treatment. It is often observed that during this time the athlete makes his best progress with respect to gains in both strength and muscle mass. Those who are on the juice all year round, who might suffer psychological consequences or who would perhaps risk the breakup of a relationship because of this should consider this drawback when taking HCG in regular in-tervals. A reduced libido and spermatogenesis due to steroids, in most cases, can be successfully cured by treatment with HCG.

Most athletes, however, use HCG at the end of a treatment in order to avoid a crash, to achieve the best possible transition into natural training. A precondition is that the steroid intake or dosage be reduced slowly and evenly before taking HCG. Although HCG causes a quick and significant increase of the endogenic plasma- testosterone level, unfortunately it is not a perfect remedy to prevent the loss of strength and mass at the end of a steroid treatment. Although HCG does stimulate endogenous testosterone production, it does not help in reestablishing the normal hypothalamic/pituitary testicular axis. The hypothalamus and pituitary are still in a refractory state after prolonged steroid usage, and remain this way while HCG is being used, because the endogenous testosterone produced as a-result of the exogenous HCG represses the endogenous LH production. Once the HCG is discontinued, the athlete must still go through a readjustment period. This is merely delayed by the HCG use. For this reason experienced athletes often take Clomid and Clenbuterol following HCG intake or they immediately begin another steroid treatment. Some take HCG merely to get off the steroids for at least two to three weeks.

HCG package insert states clearly that HCG has no known effect of fat mobilization, appetite or sense of hunger, or body fat distribution. It further states, "HCG has not been demonstrated to be effective adjunctive therapy in the treatment of obesity, it does not increase fat losses beyond that resulting from caloric restriction. At a dosage of 1500IU the pharmatestosterone level increases by 250-300% (2.5-3fold) com-pared to the initial value. The athlete should inject about 1500-2000IU of HCG every 5 days. Since the testosterone level remains considerably elevated for several days, it is unnecessary to inject HCG more than once every 5 days. The effective dosage for athletes is usually 1500IU per injection and should as already mentioned be injected every 5 days. HCG should only be taken for a few weeks. If HCG is taken by male athletes over many weeks and in high dosages, it is possible that the testes will respond poorly to a later HCG intake and a release of the body's own LH. This could result in a permanent inadequate gonadal function. HCG can in part cause side effects similar to those of injectable testosterone. A higher testosterone production also goes hand in hand with an elevated estrogen level which could result in gynecomastia. This could manifest itself in a temporary growth of breasts or reinforce already existing breast growth in men. Farsighted athletes thus combine HCG with an antiestrogen. Male athletes also report more frequent erections and an increased sexual desire. In high doses it can cause acne vulgaris and the storing of minerals and water. The last point must especially be observed since the water retention which is possible through the use of HCG could give the muscle system a puffy and watery appearance. Athletes who have already increased their endogenous testosterone level by taking Clomid and intend subsequently to take HCG could experience considerable water retention and distinct feminization symptoms (gynecomastia, tendency toward fat de-posits on the hips). This is due to the fact that high testosterone leads to a high conversion rate to estrogens. In very young athletes HCG, like anabolic steroids, can cause an early stunting of growth since it prematurely closes the epiphysial growth plates. Mood swings and high blood pressure can also be attributed to the intake of.

HCG's form of administration is also unusual. The substance choriongonadotropin is a white powdery freeze dried substance which is usually used as a compress. For each HCG ampule, includes another ampule with an injection solution containing isotonic sodium chloride. This liquid, after both ampules have been opened in a sterile manner, is injected into the HCG ampule and mixed with the dried substance. The solution is then ready for use and should be injected intramuscularly. If only part of the substance is injected the residual solution should be stored in the refrigerator. It is not necessary to store the unmixed HCG in the refrigerator; however, it should be kept out of light and below a temperature of 25C. HCG is an expensive compound, it costs approx. $30 - $40 for 1 ampule of 5000IU.