英文药名: Coly-Mycin M (Colistimethate Sodium Injection Vial)
其他名称：肠杆菌素M 多胜菌素甲
主要成分：
性状：片剂，粉针剂。
功能主治：用于治疗大肠杆菌引起的婴儿腹泻疗效显著。
用法及用量：口服：50万Ｕ／次，４次／日，首剂加倍，５～７日为１疗程。小儿每日３万Ｕ／ｋｇ，分３次。外用：制成每1ml含2000-３万Ｕ的溶液，湿敷或灌洗用。
不良反应和注意：毒副反应及注意点同多粘菌素Ｅ。本品注射毒性大，因此只作局部用药或口服，不作注射给药。
规格：盐酸多粘菌素Ｍ：片剂：50万Ｕ；粉针剂：25万Ｕ、50万Ｕ（6.7万Ｕ＝10mg）。
粉针剂：150mg。

Storage
Store the unmixed/powder vials at room temperature between 59 and 86 degrees F (15 to 30 degrees C).
Do not freeze.
Once mixed, the suspension is good for 7 days and should be refrigerated between 36 and 46 degrees F (2 to 8 degrees C).
After mixing and subsequent dilution with IV fluids, this product is stable at room temperature or refrigerated (below 77 degrees F or 25 degrees C) for 24 hours.

Overdose
If overdose is suspected, contact your local poison control center or emergency room immediately.
Symptoms of overdose may include: loss of coordination, uncontrolled eye movements (nystagmus), confusion, severe trouble breathing.
 
coly-Mycin M Parenteral Colistimethate Sodium - Inj Coly-Mycin M Parenteral Photo

How To Use
Follow all instructions for the proper mixing, dilution with the correct IV fluids, and dosing schedule.
If you have any questions regarding the use of Coly-Mycin M Parenteral, consult your pharmacist.
Once the mixing solution has been added to the vial, gently swirl or roll the vial back and forth between your hands.
Do not shake the vial.
Before using, check this product visually for any unusual particles or discoloration.
If either is present, do not use the liquid.
Inject Coly-Mycin M Parenteral into a vein (IV) or into a muscle (IM) as directed by your doctor.
The dosage and length of treatment is based on your weight, medical condition, and response to therapy.
Do not mix Coly-Mycin M Parenteral to be used at a later time.
Only use freshly mixed vials and/or IV solutions.
Antibiotics work best when the amount of medicine in your body is kept at a constant level.
Therefore, give Coly-Mycin M Parenteral at evenly spaced intervals.
Continue to use Coly-Mycin M Parenteral until the fully-prescribed amount is finished, even if symptoms disappear after a few days.
Stopping the medication too early may allow bacteria to continue to grow, which may result in a relapse of the infection.
Learn how to store and discard needles and medical supplies safely.
Consult your pharmacist.

Side Effects
Nausea/vomiting, itching, and rash may occur.
If any of these effects persist or worsen, notify your doctor promptly.
Tell your doctor immediately if any of these serious side effects occur: tingling or numbness in the arms/legs or tongue, slurred speech, dizziness, fever, lightheadedness, trouble breathing, change (decrease) in amount of urine, diarrhea.
Use of Coly-Mycin M Parenteral for prolonged or repeated periods may result in a secondary infection (e.g., oral or vaginal fungal infection).
Contact your doctor if you notice white patches in your mouth, a change in vaginal discharge, or other new symptoms.
If you notice any other effects not listed above, contact your doctor or pharmacist.

Precautions
Tell your doctor your medical history, especially of: kidney problems, any allergies.
Coly-Mycin M Parenteral may make you dizzy or drowsy.
Use caution engaging in activities requiring alertness such as driving or using machinery.
Caution is advised when using Coly-Mycin M Parenteral in the elderly because they may be more sensitive to the effects of Coly-Mycin M Parenteral.
Coly-Mycin M Parenteral should be used only when clearly needed during pregnancy.
Discuss the risks and benefits with your doctor.
Based on information for similar drugs, Coly-Mycin M Parenteral may pass into breast milk.
Therefore, consult your doctor before breast-feeding.

Missed Dose
If you miss a dose, use it as soon as you remember.
If it is near the time of the next dose, skip the missed dose and resume your usual dosing schedule.
Do not double the dose to catch up.

Drug Interactions
Coly-Mycin M Parenteral is not recommended for use with aminoglycoside antibiotics (e.g., gentamicin, tobramycin), polymyxin, or sodium cephalothin.
Using Coly-Mycin M Parenteral with these products may cause serious nerve side effects or kidney problems.
Ask your doctor or pharmacist for more details.
Tell your doctor of all prescription and nonprescription medication you may use, especially: certain muscle relaxants (e.g., curare-like drugs such as decamethonium, ether, gallamine, sodium citrate, succinylcholine, or tubocurarine), live vaccines (e.g., oral polio vaccine).
Do not start or stop any medicine without doctor or pharmacist approval.