中文名称吡罗昔康
中文别名吡啶苯噻酰胺; 吡氧噻嗪; 2-甲基-4-羟基-N-(2-吡啶基)-2H-1,2-苯并噻嗪-3-甲酰胺-1,1-二氧化物
英文名称piroxicam
英文别名PIROXICAM; 4-hydroxy-2-methyl-n-2-pyridinyl-2h-1,2-benzothiazine-3-carboxamide 1,1-dioxide
EINECS252-974-3
分子式C15H13N3O4S
分子量331.34
分子结构
药理：抑制体内环氧化酶（环氧化酶）I及II型，从而减少前列腺素（前列腺素）的产生
用途：治疗急性及慢性类风湿性关节炎及骨关节炎的症状
剂量：口服避孕药的每天一次，每次10毫克 - 20毫克
用药禁忌：
对吡​​罗昔康及其药物成份敏感的人士忌用升
急性消化道出血（主动胃肠道出血）
怀孕妇女（第三妊娠期）        
用药注意：
以下人士要小心使用：
充血性心脏衰竭
高血压
肝，肾功能不全的人士
曾患有消化道溃疡或出血
正在服用抗凝血药（抗凝血剂）或类固醇（类固醇）
常见副作用：可引起肠胃不适，恶心，呕吐，腹泻
其他副作用：皮疹，晕眩，水肿或消化道溃疡
药物相互作用：
此药可增强抗凝血药华法林（华法林）的功效，可能增加出血的机会
与其他非类固醇消炎止痛药（NSAIDs）并用可能会增加药物的副作用病患者及家属注意事项：
应在进餐时或餐后服用，以减轻肠胃不适的机会
如出现肠胃溃疡或出血的征兆或症状时，应立即向医生求诊。

Piroxicam
IMPORTANT WARNING:
People who take nonsteroidal anti-inflammatory medications (NSAIDs) (other than aspirin) such as piroxicam may have a higher risk of having a heart attack or a stroke than people
who do not take these medications.
These events may happen without warning and may cause death. This risk may be higher for people who take NSAIDs for a long time. Tell your doctor if you or anyone in your family has or has ever had heart disease, a heart attack, or a stroke, if you smoke, and if you
have or have ever had high cholesterol, high blood pressure, or diabetes. Get emergency medical help right away if you experience any of the following symptoms: chest pain, shortness of breath, weakness in one part or side of the body, or slurred speech.
If you will be undergoing a coronary artery bypass graft (CABG; a type of heart surgery), you should not take piroxicam right before or right after the surgery.
NSAIDs such as piroxicam may cause ulcers, bleeding, or holes in the stomach or intestine. These problems may develop at any time during treatment, may happen without warning symptoms, and may cause death. The risk may be higher for people who take NSAIDs for a long time, are older in age, have poor health, or drink large amounts of alcohol while you are taking piroxicam.
Tell your doctor if you take any of the following medications: anticoagulants ('blood thinners') such as  warfarin (Coumadin); aspirin; other NSAIDs such as ibuprofen (Advil, Motrin) and naproxen (Aleve, Naprosyn); or oral steroids such as dexamethasone (Decadron, Dexone), methylprednisolone (Medrol), and prednisone (Deltasone). Also tell your doctor if you have or have ever had ulcers or bleeding in your stomach or intestines or other bleeding disorders. If you experience any of the following symptoms, stop taking piroxicam and call your doctor: stomach pain, heartburn, vomiting a substance that is bloody or looks like coffee grounds, blood in the stool, or black and tarry stools.
Keep all appointments with your doctor and the laboratory.
Your doctor will monitor your symptoms carefully and will probably order certain tests to check your body's response to piroxicam. Be sure to tell your doctor how you are feeling so that your doctor can prescribe the right amount of medication to treat your condition with the lowest risk of serious side effects.
Your doctor or pharmacist will give you the manufacturer's patient information sheet (Medication Guide) when you begin treatment with piroxicam and each time you refill your
prescription.
Read the information carefully and ask your doctor or pharmacist if you have any questions.          
Why is this medication prescribed?
Piroxicam is used to relieve pain, tenderness, swelling, and stiffness fness caused by osteoarthritis (arthritis caused by a breakdown of the lining of the joints) and rheumatoid arthritis (arthritis caused by swelling of the lining of the joints). Piroxicam is in a class of medications called NSAIDs.
It works by stopping the body's production of a substance that causes pain, fever, and inflammation.
How should this medicine be used?
Piroxicam comes as a capsule to take by mouth. It is usually taken once or twice a day. Take piroxicam at around the same time(s) every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take piroxicam exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.
Piroxicam will help control your symptoms but will not cure your condition. It may take 8-12 weeks or longer before you feel the full benefit of piroxicam.
Other uses for this medicine
Piroxicam is also sometimes used to treat gouty arthritis (attacks of severe joint pain and swelling caused by a build-up of certain substances in the joints) and ankylosing
spondylitis (arthritis that mainly affects the spine). It is also sometimes used to relieve muscle pain and swelling, menstrual pain, and pain after surgery or childbirth. Talk to your doctor about the risks of using this medication for your condition.
What special precautions should I follow?
Before taking piroxicam,tell your doctor and pharmacist if you are allergic to piroxicam, aspirin,or other NSAIDs such as ibuprofen (Advil, Motrin) and naproxen (Aleve, Naprosyn), or any other medications.
tell your doctor and pharmacist what prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take. Be sure to mention the medications listed in the IMPORTANT WARNING section and any of the following: angiotensin-converting enzyme (ACE) inhibitors such as benazepril (Lotensin), captopril (Capoten), enalapril (Vasotec), fosinopril (Monopril), lisinopril (Prinivil,
Zestril), moexipril (Univasc), perindopril (Aceon), quinapril (Accupril), ramipril (Altace), and trandolapril (Mavik); diuretics ('water pills'); lithium (Eskalith, Lithobid); medications for diabetes; methotrexate (Rheumatrex); and phenytoin (Dilantin) .
tell your doctor if you have or have ever had asthma, especially if you also have frequent stuffy or runny nose or nasal polyps (swelling of the lining of the nose); swelling of
the hands, feet, ankles, or lower legs ; or liver, or kidney disease.
tell your doctor if you are pregnant, especially if you are in the last few months of your pregnancy, you plan to become pregnant, or you are breast-feeding. If you become pregnant
while taking piroxicam, call your doctor.
if you are having surgery, including dental surgery, tell the doctor or dentist that you are taking piroxicam.
What special dietary instructions should I follow?   Return to top Unless your doctor tells you otherwise, continue your normal diet.
What should I do if I forget a dose?
Take the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one.
What side effects can this medication cause?
Piroxicam may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away: diarrhea constipation gas headache dizziness ringing in the ears Some side effects can be serious. If you experience any of the following symptoms or those mentioned in the IMPORTANT WARNING section, call your doctor immediately. Do not take any more
piroxicam until you speak to your doctor.
vision problems
unexplained weight gain fever blisters joint pain rash itching hives swelling of the eyes, face, lips, tongue, throat, arms, hands, feet, ankles, or lower legs difficulty breathing or swallowing hoarseness pale skin fast hearbeat excessive tiredness unusual bleeding or bruising lack of energy upset stomach loss of appetite pain in the upper right part of the stomach flu-like symptoms yellowing of the skin or eyes cloudy, discolored, or bloody urine back pain difficult or painful urination Piroxicam may cause other side effects. Call your doctor if you have any unusual problems while taking this medication.
What storage conditions are needed for this medicine?
Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the
bathroom).
Throw away any medication that is outdated or no longer needed. Talk to your pharmacist about the proper disposal of your medication.
In case of emergency/overdose
In case of overdose, call your local poison control center at 1-800-222-1222. If the victim has collapsed or is not breathing, call local emergency services at 911.
Symptoms of overdose may include:
lack of energy
drowsiness
upset stomach
vomiting
stomach pain
bloody, black, or tarry stools vomiting a substance that is bloody or looks like coffee
grounds difficulty breathing coma (loss of consciousness for a period of time)
What other information should I know?
Do not let anyone else take your medication. Ask your pharmacist any questions you have about refilling your prescription.
It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.
附件:
20106621561827.PDF

---------------------------------------------------------------
产地国家: 香港
原产地英文商品名:
Karoxicam capsule 10mg/cap 1000caps/box
原产地英文药品名:
Piroxicam
中文参考商品译名:
Karoxicam胶囊 10毫克/胶囊 1000胶囊/盒
中文参考药品译名:
吡羅昔康
生产厂家中文参考译名:
KAREN LAB
生产厂家英文名:
KAREN LAB