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当前位置:药品说明书与价格首页 >> 皮肤性病 >> 新药动态 >> 疱疹神经痛治疗药Qutenza(辣椒碱)8%贴剂获得FDA批准临床使用

疱疹神经痛治疗药Qutenza(辣椒碱)8%贴剂获得FDA批准临床使用

2010-02-26 11:13:12  作者:新特药房  来源:中国医学论坛报  浏览次数:200  文字大小:【】【】【
简介: Qutenza(辣椒碱)8%贴剂是一种用于减少带状疱疹性神经痛的处方贴剂,最近刚获得FDA批准,是首个且仅有的辣椒素处方产品,辣椒素是辣椒辣味的主要成分,Qutenza中含有一种合成辣椒素。 疼痛部位贴上 ...

Qutenza(辣椒碱)8%贴剂是一种用于减少带状疱疹性神经痛的处方贴剂,最近刚获得FDA批准,是首个且仅有的辣椒素处方产品,辣椒素是辣椒辣味的主要成分,Qutenza中含有一种合成辣椒素。
     疼痛部位贴上这种贴剂1小时后,可减少带状疱疹引起的神经痛,药力可持续12周,经医生或专业护理人员允许方可使用,可单独使用或和其它镇痛药物合用而不会发生药物之间相互作用。
    带状疱疹是一种由病毒引起的疼痛性病毒感染疾病,美国每年患病人数约有一百万。带状疱疹并发症——带状疱疹神经痛(PHN)——是由带状疱疹病毒损伤神经造成的一种慢性症状,约五分之一带状疱疹患病者因此长期饱受疼痛之苦。这种疼痛能在典型皮疹消失后长时间存在,影响患者睡眠、心情、工作和日常生活。PHN发病风险随年龄增长,年龄超过50岁以及在急性带状疱疹期间出现严重疼痛和皮疹的患者尤其容易患病。

Indication

Qutenza® is indicated for the management of neuropathic pain associated with postherpetic neuralgia.

About Qutenza® (capsaicin) 8% patch

Qutenza® contains capsaicin in a local dermal delivery system. The capsaicin in Qutenza® is a synthetic equivalent of the naturally occurring compound found in chili peppers.

Important Safety Information

Qutenza® is administered by a physician or a health professional under the close supervision of a physician. Qutenza® may be administered every 3 months or as warranted by the return of pain, but not more frequently than every 3 months. In clinical trials, the most common adverse reactions were application site redness, pain, itching, and papules. The majority of these reactions were transient and self limited. Among patients treated with Qutenza®, 1% discontinued prematurely due to an adverse event. Serious adverse reactions included application-site pain and increased blood pressure. Blood pressure increases during or shortly after Qutenza® treatment were on average less than 10 mm Hg, although some patients had greater increases and these changes lasted for approximately 2 hours after patch removal.

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