部分中文溴芬酸处方资料(仅供参考) Bromday滴眼液(溴芬酸滴眼液) 药理分类: 活性成分: 药理作用: 临床试验: 成人: 儿童: 警告/注意事项: 互动: 不良反应: 剂型、包装: BROMDAY Pharmacological Class:NSAID. Active Ingredient(s):Bromfenac 0.09%, oph soln; contains benzalkonium chloride, sulfites. Indication(s):Post-operative inflammation and reduction of ocular pain following cataract extraction. Pharmacology:Bromfenac is a nonsteroidal anti-inflammatory drug (NSAID) that has anti-inflammatory activity. The mechanism of action is thought to be due to its ability to block prostaglandin synthesis by inhibiting cyclooxygenase 1 and 2. Clinical Trials:Clinical efficacy was evaluated in three, randomized, double-masked, placebo-controlled trials in which patients requiring cataract surgery were assigned to Bromday or placebo. Patients were dosed with one drop per eye starting the day before surgery and continuing for 14 days. The primary endpoint was clearing of ocular inflammation by day 15. An additional efficacy endpoint was the number of patients who were pain free on day 1 after cataract surgery. In two of the three studies, Bromday ophthalmic solution had statistically significant higher incidence of completely clearing inflammation (46–47% vs. 25–29%) and also had a statisitically signficant higher incidence of subjects that were pain free at day 1 post cataract surgery (83–89% vs. 51–71%). Legal Classification:Rx Adults:≥18yrs: 1 drop in affected eye(s) once daily starting 1 day before surgery, continued on day of surgery, and for 14 days post-op. May be given with other topical ophthalmics (eg, alpha-agonists, beta-blockers, carbonic anhydrase inhibitors, cycloplegics, mydriatics); administer at least 5 minutes apart. Children:<18yrs: not recommended. Warnings/Precautions:Bleeding tendencies. May slow or delay wound healing. Complicated/repeat ocular surgeries. Corneal defects/denervation. Ocular surface diseases. Rheumatoid arthritis. Diabetes. Monitor cornea; discontinue if corneal epithelial breakdown occurs. Risk of corneal adverse events may be increased if used >24hrs before surgery, or beyond 14-days post-op. Contact lenses (remove during therapy). Pregnancy (Cat.C; avoid during late pregnancy). Nursing mothers. Interaction(s):Concomitant topical corticosteroids may potentiate healing problems. Caution with concomitant drugs that prolong bleeding time. Adverse Reaction(s):Ocular effects (eg, abnormal sensation, conjunctival hyperemia, burning, stinging, pain, pruritus, redness, iritis), headache; keratitis, corneal reactions (eg, epithelial breakdown, thinning, erosion, ulceration/perforation). |
溴芬酸纳滴眼液(BROMDAY 0.09% EYE DROPS 1.7ML/BOTTLE)简介:
部分中文溴芬酸处方资料(仅供参考)
Bromday滴眼液(溴芬酸滴眼液) 制造商: Ista药厂
药理分类: 甾体抗炎药。
活性成分: 溴芬酸溶液0.09%;含有苯扎氯铵,亚硫酸盐。 适应症: 术后眼部炎症和 ... 责任编辑:admin |
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