英文药名：RIZABEN Eye Drops 0.5％（Tranilast）
中文药名：曲尼司特滴眼液
生产厂家：KISSEI药品
类别名称
过敏性结膜炎的治疗剤
欧文商標名
RIZABEN Eye Drops 0.5％
一般名トラニラスト（JAN）
Tranilast（JAN，INN）
化学名：
2-{[(2E)-3-(3,4-Dimethoxyphenyl)prop-2-enoyl]amino}benzoic acid
構造式
分子式：C18H17NO5
分子量：327.33
性状
此产品是淡黄色的结晶或结晶粉末。
的产物N，易溶于N-二甲基甲酰胺，乙腈，微溶于甲醇或乙醇（99.5），并且几乎不溶于水。
本产品是逐渐浅褐色的光。
此产品是观察晶体多晶型物
熔点
207〜210℃
操作注意事项
当保存这种药物在冰箱等，且应避免的晶体析出。
适应症
抑制组胺引起过敏反应的释放，改善眼睛发痒由于过敏性结膜炎，症状，如充血。
剂量和给药方法
成年人一次1-2滴，四次（早上，中午，晚上就寝）。请严格按照使用说明。
包装规格
55mL×5瓶,5mL×10瓶,5mL×50瓶
制造厂商
KISSEI药品有限公司
RIZABEN Eye Drops 0.5％（Tranilast）
Brand name : RIZABEN Eye Drops 0.5％
Active ingredient: Tranilast
Dosage form: faintly yellow limpid ophthalmic solution
Print on wrapping: リザベン点眼液0.5％
Effects of this medicine
This medicine inhibits chemical mediator released from mast cell by antigen prime to show antiallergic effect. It consequently relieves symptoms such as eye itching, eye discharge, blood shot eye, swelling in eyelid or foreign body sensation.
It is usually used to treat allergic conjunctivitis.
Before using this medicine, be sure to tell your doctor and pharmacist
•If you have ever experienced any allergic reaction (itch, rash etc.) to any medicine.
•If you are pregnant or breastfeeding.
•If you are taking any other medicinal products. (Some medicines may interact to enhance or diminish medicinal effects. Beware of over-the-counter medicines and dietary supplements as well as other prescription medicines.)
Dosing schedule (How to take this medicine)
•Your dosing schedule prescribed by your doctor is <<to be written by a healthcare professional>>
•General dosage regimen: For adults, apply 1-2 drops at a time, 4 times (morning, daytime, evening and before sleeping) a day. Strictly follow the instructions of your doctor/pharmacist.
•Apply a dose as soon as possible. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. DO NOT use double doses to make up for the missed dose.
•If you used too much of the medicine (more than ordered), check with your doctor/pharmacist.
•Do not stop using the medicine without the instructions of your doctor.
Precautions while taking this medicine
• Possible adverse reactions to this medicine
Common side effects are reported as below. If any of them occurs, check with your doctor/pharmacist: irritation, eye-smarting, redness around the eye or rim, itching, blood shot eye, swelling in eyelid, etc.
The symptoms described below are rarely seen as initial symptoms of the adverse reactions indicated in brackets. If any of these symptoms occur, stop taking this medicine and see your doctor immediately.
No pertinent entries.
The above symptoms do not describe all the adverse reactions to this medicine. Consult with your doctor or pharmacist if you notice any symptoms of concern other than those listed above.
Storage conditions and other information
•Keep out the reach of children. Store away from direct sunlight and heat.
•Discard the remainder. Do not store them.
Kissei Pharmaceutical Co., Ltd.External
Published: 8/2007
The information on this sheet is based on approvals granted by the Japanese regulatory authority. Approval details may vary by country. Medicines have adverse reactions (risks) as well as efficacies (benefits). It is important to minimize adverse reactions and maximize efficacy. To obtain a better therapeutic response, patients should understand their medication and cooperate with the treatment.
http://www.kegg.jp/medicus-bin/japic_med?japic_code=00053012