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当前位置:药品说明书与价格首页 >> 妇科药物 >> 其他治疗药 >> LO LOESTRIN FE(复合口服避孕药)

LO LOESTRIN FE(复合口服避孕药)

2013-05-10 23:38:39  作者:新特药房  来源:互联网  浏览次数:298  文字大小:【】【】【
简介:Generic Name and Formulations:Norethindrone acetate 1mg, ethinyl estradiol 10mcg (24 tabs), ethinyl estradiol 10mcg (2 tabs); inert+ (2 tabs); +contains ferrous fumarate 75mg. Company:Warner Chi ...

Generic Name and Formulations:
Norethindrone acetate 1mg, ethinyl estradiol 10mcg (24 tabs), ethinyl estradiol 10mcg (2 tabs); inert+ (2 tabs); +contains ferrous fumarate 75mg.

Company:
Warner Chilcott Laboratories

Indications for LO LOESTRIN Fe:
Oral contraception.

Adult Dose for LO LOESTRIN Fe:
1 tab daily for 28 days; repeat. Take at the same time daily, in the correct order. Start Day 1 of menstrual cycle. Allow at least 4 weeks postpartum, if not breastfeeding, to begin cycle; use backup method for first 7 days.

Children's Dose for LO LOESTRIN Fe:
Premenarchal: not applicable.

Pharmacological Class:
Progestin + estrogen.

Contraindications:
High risk of arterial or venous thrombotic disease (eg, smokers or migraineurs over age 35, history of DVT or thromboembolism, cerebrovascular or coronary artery disease, thrombogenic valvular disease, atrial fibrillation, subacute bacterial endocarditis, hypercoagulopathies, uncontrolled hypertension, diabetes with vascular disease, headaches with focal neurologic symptoms). Breast or other estrogen or progestin-sensitive neoplasms. Hepatic disease or tumors. Undiagnosed abnormal uterine bleeding. Pregnancy (Cat.X).

Warnings/Precautions:
Not for use in women with BMI >35kg/m2. Discontinue if thrombotic event, unexplained visual changes, or jaundice occurs, and at least 4 weeks before through 2 weeks after surgery associated with increased risk of thromboembolism. Gallbladder disease. Diabetes. Prediabetes. Uncontrolled dyslipidemias. Hypertriglyceridemia. Pregnancy-related cholestasis. Depression. Evaluate significant changes in headaches, irregular uterine bleeding, amenorrhea. Monitor blood pressure. Do regular complete physical exams. Nursing mothers: not recommended.

Interactions:
May be antagonized by CYP3A4 or other enzyme inducers (eg, barbiturates, bosentan, carbamazepine, felbamate, griseofulvin, oxcarbazepine, phenytoin, rifampin, St. John’s wort, topiramate); use backup contraception. May be affected by protease inhibitors, NNRTIs, atorvastatin, acetaminophen, ascorbic acid, itraconazole, ketoconazole. May antagonize lamotrigine. May affect laboratory tests (eg, coagulation factors, lipids, glucose tolerance, binding proteins). May need dose adjustment of thyroid hormones.

Adverse Reactions:
Headache, nausea, vomiting, bleeding irregularities, dysmenorrhea, weight change, mastodynia, acne, abdominal pain, anxiety, depression; angioedema, chloasma, others (see literature).

How Supplied:
Packs—5

责任编辑:admin


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