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当前位置:药品说明书与价格首页 >> 抗感染类 >> 药品目录 >> 抗真菌类 >> 特治星(注射用哌拉西林钠/他唑巴坦钠)

特治星(注射用哌拉西林钠/他唑巴坦钠)

——哌拉西林/他唑巴坦

2005-03-11 18:19:33  作者:新特药房  来源:中国新特药网天津分站  浏览次数:375  文字大小:【】【】【

【药品名称】特治星
【通用名称】注射用哌拉西林钠/他唑巴坦钠
【生产企业】Wyeth-Ayerst Lederle Inc.
【产品规格】4.5g
【产品单位】支
【零售价格】192.00元

【药品名称】
通用名:注射用哌拉西林钠/他唑巴坦钠 
商品名:特治星   
英文名:Piperacillin-Tazobactam, Tazocin, Zosyn
汉语拼音:Zhusheyong Pailaxilinna /TazuobatanNa
【成 份】
哌拉西林4g,他佐巴坦钠盐Na 500mg.
【性 状】
本品为白色粉末或类白色疏松块状物或粉末,无臭,味苦,极具引湿性。
【作用类别】
抗感染药处方药西药。
【适应症】
敏感细菌所致的呼吸道感染,泌尿道感染,腹腔内感染,皮肤及软组织感染,腹腔内感染,皮肤及软组织感染 ,细菌性败血症,妇科感染,患中性粒性细胞减少症病人的细菌感染,骨与关节感染。
【用法用量】
成人及12岁以上的青少年4.5g/6-12 hr一次缓慢静脉注射,静脉滴注或肌肉注射。治疗急性感染,疗程至少在5天以上,并在临床症状缓解或体温恢复后继酌情减量或延长给药间隔时间。
【不良反应】
1.特治星常见不良反应
(1)皮肤反应:皮疹、瘙痒等。
(2)消化道反应:如腹泻、恶心、呕吐等。
(3)过敏反应。
(4)局部反应:如注射局部刺激反应、疼痛、静脉炎、血栓性静脉炎和水肿等。
(5)其他反应:如血小板减少、胰腺炎、发热、发热伴嗜酸粒细胞增多、血清氨基转移酶升高等;这些反应发生在本品与氨基糖苷类药物联合治疗时。
2.此外,本品尚可见下列不良反应。
(1)腹泻、便秘、恶心、呕吐、腹痛、消化不良等。
(2)斑丘疹、疱疹、荨麻疹、湿疹等。
(3)烦躁、头晕、焦虑等。
(4)其他反应:如鼻炎、呼吸困难等。
【注意事项】
定期检查肚、肾功能,造血功能,凝血指标。妊娠和哺乳妇女慎用。
【药物相互作用】
勿与丙磺舒,妥布霉素,氨基糖甙类抗生素,非极化肌松剂合用。
【贮藏】遮光、密封,在干燥阴凉处保存。
【包装】1支/盒
【有效期】3年
【批件信息】H20070090
【生产厂家】美国立达哌拉西林公司

TAZOCIN

WHAT IS IN THIS MEDICINE?
The name of this medicine is Tazocin. Tazocin comes in packs containing one small bottle of powder which must be dissolved into a solution before it is given to you by injection or infusion (a slow injection or "drip") into your vein. Tazocin contains two active ingredients, piperacillin and tazobactam and no other ingredients. It is available in the following strengths:
Tazocin 2.25g contains the equivalent of 2g piperacillin and 250mg of tazobactam.
Tazocin 4.5g contains the equivalent of 4g piperacillin and 500mg of tazobactam.
Tazocin 4.5g also comes in an infusion pack where it is supplied with a 50ml bottle of Water for Injections to dissolve the powder in before use.

MARKETING AUTHORISATION HOLOER
John Wyeth & Brother Limited
Trading as:
Wyeth Pharmaceuticals
Huntercombe Lane South,
Taplow, Maidenhead, Berkshire, SL6 0PH, UK

MANUFACTURER

Wyeth Laboratories

Wyeth Lederle S.P.A

New Lane

Via Franco Gorgone

Havant

 Zona Industriale

Hants P09 2NG

95030 Catania CT, Italy


WHAT DOES THIS MEDICINE DO?
Piperacillin belongs to the group of medicines known as 'broad spectrum penicillin antibiotics'. It can kill many kinds of bacteria. Tazobactam can prevent some bacteria becoming resistant to the effects of piperacillin. This means that some bacteria, which are normally not killed by piperacillin, are killed when piperacillin and tazobactam are given together.
Tazocin is used to treat bacterial infections such as those affecting your chest, urinary tract, blood, abdomen or skin. Tazocin may also be used with medicines known as 'aminoglycosides' to treat infections in patients who are unable to fight infections normally.

BEFORE RECEIVING THIS MEDICINE
If the answer to any of the following questions is 'yes' you should tell your doctor as this medicine may not be suitable for you.
- Are you allergic to Tazocin, or have you had allergic reactions to antibiotics known as penicillins or cephalosporins, or to medicines called beta-Iactamase inhibitors (ask your doctor if you are not sure?)
- Is the patient aged 12 years or under? Not all infections in children may be treated with Tazocin.
- Are you pregnant think you might be pregnant or are breast feeding?
- Do you have kidney or liver problems, or do you receive haemodialysis treatment? Your doctor may check how well your kidneys are working before he gives you this medicine and you may have regular checks whilst taking your medicine.
- Do you have low levels of potassium in your blood or are you taking diuretics (for heart problems or high blood pressure) or drugs for cancer (ask your doctor if you are not sure)? Your doctor might take a blood sample from time to time for testing.
- Are you on a low sodium diet?
- Are you taking any other medicines, including those you have bought without a prescription? In particular, probenecid (for gout), medicines to thin your blood or to treat blood clots (e.g. heparin, warfarin or aspirin), or a drug called methotrexate (for cancer, arthritis or psoriasis).
You should also tell your doctor if you are going to have a general anaesthetic.
If you are being treated for gonorrhoea, you should be tested for syphilis before taking Tazocin.

RECEIVING THIS MEDICINE
Your doctor will give Tazocin to you by slow injection or through a drip into one of your veins.
The usual adult dose of Tazocin is 4.5g given every 8 hours. However, your doctor will decide on the exact dose depending on the severity of your infection. Children aged 2-12 years may receive a lower dose for infections in or around the abdomen. (The usual dose for children is 112.5mg per kg of body weight every 8 hours, up to the adult dose).
If your body cannot fight infections well, Tazocin may be used in combination with another drug, called an 'aminoglycoside', which will also be given into one of your veins. In this case, the usual dose of Tazocin is 4.5g every 6 hours. However, your doctor may give a lower dose to children aged 12 years and under. (The usual dose for children is 90mg per kg of body weight every 6 hours, up to the adult dose).
If you are given Tazocin in combination with an 'aminoglycoside', the two drugs should not be given to you in the same syringe or drip.
You will be given Tazocin until the signs of infection have disappeared and then treatment will usually be continued for a further 48 hours to make sure the infection has gone completely.
If you have kidney or liver problems, your doctor may need to adjust the dose of Tazocin or how often it is given. Your doctor may also want to test your blood to make sure that your treatment is working, especially if you take Tazocin for a long time

AFTER RECEIVING THIS MEDICINE
As well as helping with your illness, Tazocin may cause unwanted side effects in some patients.
If you experience persistent bloody diarrhoea, a severe allergic reaction (seen as swelling of the face or extreme difficulty breathing), widespread redness of the skin, or severe peeling of the skin, tell your doctor or nurse immediately. The most common side effects are diarrhoea, skin rashes, and feeling or being sick.
You may experience pain, swelling, warmth or redness around the site of injection.
More rarely, you may experience abnormal bruising and bleeding, itching, an itchy rash, eczema or other types of skin reactions, mild allergic reactions and super-infections (usually seen as thrush), increased sweating, fever or hot flushes, muscle pain or weakness, pain in the joints, headache, twitching, convulsions, tiredness, inability to sleep, hallucinations, dry or sore mouth, mouth ulcers, water retention, heartburn, abdominal pain or discomfort, constipation, soft or loose stools.
Unwanted effects of Tazocin that you may not be aware of whilst taking your medicine include low blood pressure (seen as dizziness on standing), inflammation of the veins, changes in the number of red or white blood cells or platelets, or the levels of potassium, glucose or protein in your blood; temporary increases in levels of liver enzymes or bilirubin in the blood, changes in liver function (causing yellowing of the skin or whites of your eyes, itchy skin, darker urine and paler stools), or, rarely, changes in kidney function. During your treatment you may have some tests to measure any changes.
If you experience any of these effects, or any other symptoms not listed above, please contact your doctor or nurse.

STORING THIS MEDICINE
The hospital pharmacy will ensure Tazocin powder for injection is not stored above 25°C and it is used before the expiry date printed on the label.
Made up solutions prepared in sterile conditions may be stored for up to 24 hours in a refrigerator (2°C - 8°C).

OTHER INFORMATION
The information in this leaflet applies only to Tazocin. If you would like more information about Tazocin, have any questions or you are not sure about anything, you should ask your doctor or nurse.
Leaflet revised: 30 January 2004
*Trade mark

药品价格(单位:元)
编号 药品名称 通用名 产地 规格 单位 参考价
70039 特治星(注射用哌拉西林钠/他唑巴坦钠) 哌拉西林/他唑巴坦 美国惠氏 4.5g,粉针剂 192
*声明:以上药品价格仅作参考,实际价格以药房各分店为准。

责任编辑:


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