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随着去年12月来自丹麦的利奥制药公司正式进入中国，其主打品牌得肤宝也即将投放中国市场。据悉，得肤宝（Daivobet）是利奥制药公司于2005年全面推出市场的一种治疗银屑病的新产品，用于治疗稳定性斑块状银屑病。 得肤宝（Daivobet）是利奥制药治疗银屑病的优质产品，起效快，效果好，每天使用一次，是治疗银屑病的首选用药。全球已经有数万银屑病患者使用过得肤宝（Daivobet），众多文献也证实了其在临床应用中的有效性。同时，长达52周的随机临床实验也证实得肤宝（Daivobet）在银屑病长期治疗中的安全性和有效性。 得肤宝软膏（Daivobet）药品信息 成份：每1g含钙泊三醇Calcipotriol 50ug，倍他米松 Betamethasone 0.5mg； 适应症：用于治疗稳定性斑块状银屑病。 用法用量：每日1次将本药少量涂于患处皮肤，4周为一疗程，每天最大剂量不超过15g，每周最大剂量不超过100g，治疗面积不应超过体表面积的30%。1个疗程结束后，可酌情重复治疗。 不良反应：瘙痒症、皮疹、皮肤烧灼感。少见皮肤疼痛或刺激感，皮炎，红斑，银屑病加重，毛囊炎，应用部位色素沉着。罕见脓疱型银屑病。 禁忌：伴有钙代谢紊乱的患者；点滴状，红皮病型，剥脱性和脓疱型银屑病患者；严重肾或肝功能障碍者；18岁以下患者禁用。 注意事项：使用时注意防止药物沾在头皮，脸，口及眼睛，每次使用后必须洗手。孕妇慎用。哺乳妇女不能将本品涂敷在乳房上。 药物相互作用：应避免与其他的甾体类药物同时使用。
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Body Psoriasis
Short about treatment of body psoriasis
Topical treatments (e.g. ointments and creams) are first-line treatments for body psoriasis. A topical medication is used externally, applied directly onto the psoriatic area (e.g. elbow or knee).
The treatment should work fast and be effective
A product with a once-daily dosage will be time-saving
Some frequently used topical products for body psoriasis are mentioned below.
Combination therapy products
Calcipotriol and betamethasone dipropionate ointment
This is a combination ointment containing a vitamin D analogue, calcipotriol, and a potent topical steroid, betamethasone dipropionate. This ointment treats the symptoms of body psoriasis (i.e. reduce itching, scaling and redness) and helps to normalize your skin cells. This combination ointment should be applied once daily.
Betamethasone diproprionate and salicylic acid ointment
This combination ointment contains a potent topical steroid, betamethasone diproprionate and salicylic acid. The topical steroid treats the symptoms of body psoriasis (reduce itching and inflammation) and the salicylic acid works as a descaling agent. This ointment should normally be applied twice daily.
Monotherapy products
Calcipotriol cream
Calcipotriol is a vitamin D analogue often used for the treatment of body psoriasis. Calcipotriol works by regulating and normalizing the growth of skin cells. Calcipotriol cream should normally be applied twice daily in order to obtain an optimal effect.
Corticosteroids (also known as 'plain steroids')
Corticosteroids have been used for many years in the treatment of psoriasis. They come in a variety of different vehicles, such as lotions, creams, gels and ointments. Please notice that some 'over-the-counter' steroids ('over the counter' means no prescription required) sold in some countries may be too weak to be effective on psoriasis.
Application
How much cream or ointment to apply?
When using a topical treatment for your body psoriasis a general dosage rule apply. This is known as the Finger Tip Unit (FTU). The FTU is a keystone in how to dose the ointment or cream correctly.
The FTU is a simple, individual measure telling you how much cream or ointment to apply to a psoriatic lesion. 1 FTU (squeezed from a tube with a standard 5 mm nozzle) is enough to treat an area of skin twice the size of the flat of an adult's hand with the fingers together. So, adult hands can be used to measure the areas of skin affected by psoriasis and then estimate the amount of cream or ointment required per application - see picture below.
Thus 1 FTU will be sufficient to cover a body area of 2 hands, and 2 FTUs will cover a body area of 4 hands.
Emollients
Emollients or moisturizers are very important in the management of body psoriasis. They can not be categorised as medical products but they help to moisture the skin and to ease the dryness of the skin. Can be bought in many different formulations and brands.
Please notice that when you apply emollients, these should be applied liberally. Apply as much emollient as you feel comfortable with. So for emollients the FTU rule does not apply.
For more information about symptoms of psoriasis, please click here