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ENDOMETRIN插入栓剂

2011-01-06 15:25:35  作者:新特药房  来源:中国新特药网天津分站  浏览次数:960  文字大小:【】【】【
简介: 名 称 通用名:黄体酮别 名:孕酮、助孕素英文名:Progesterone化学名称:孕甾-4-烯-3,20-二酮类 别 孕激素类药药 理 本品为孕激素类药,具有孕激素的一般作用。在月经周期后期能使子宫内膜为分泌 ...

名  称
通用名:黄体酮
别  名:孕酮、助孕素
英文名:Progesterone
化学名称:孕甾-4-烯-3,20-二酮
类  别
孕激素类药
药  理
本品为孕激素类药,具有孕激素的一般作用。在月经周期后期能使子宫内膜为分泌期改变,为孕卵着床提供有利条件,在受精卵植入后,胎盘形成,可减少妊娠子宫的兴奋性,使胎儿能安全生长。在与雌激素共同作用时,可促使乳房发育,为产乳做准备。本品可通过对下丘脑的负反馈,抑制垂体前叶促黄体生成激素的释放,使卵泡不能发育成熟,抑制卵巢的排卵过程。
 
临床适应症状
用于月经失调,如闭经和功能性子宫出血、黄体功能不足、先兆流产和习惯性流产(因黄体不足引起者)、经前期紧张综合症的治疗
临床不良反应
偶见恶心、头晕及头痛、倦怠感、寻麻疹、乳房肿胀、长期连续应用可月经减少或闭经、肝功能异常、浮肿、体重增加等。
贮  藏
遮光,密封保存


 
Endometrin

 

Generic Name: progesterone vaginal (proe JESS te role VAJ in ul)
Brand Names: Endometrin

What is Endometrin?
Endometrin is a vaginal insert containing progesterone 100mg. Progesterone is a female hormone important for ovulation and menstruation. Progesterone causes changes in the lining of your uterus, making it easier for a fertilized egg to attach to the uterus at the beginning of pregnancy. Endometrin helps your body maintain the pregnancy.

Endometrin is used in fertility treatment as part of Assisted Reproductive Technology (ART) for women unable to get pregnant due to a lack of natural progesterone in the body.

Endometrin may also be used for other purposes not listed.

Important information about Endometrin
Do not use Endometrin without your doctor's consent if you are pregnant, unless you are using the medication as part of your fertility treatment. Using Endometrin can increase your risk of blood clots, stroke, heart attack, or breast cancer. You should not use Endometrin if you have: a history of stroke or blood clot, circulation problems, severe liver disease, a hormone-related cancer such as breast or uterine cancer, abnormal vaginal bleeding, or if you have recently had a tubal pregnancy or an incomplete abortion.
When used as part of fertility treatment, Endometrin may be given for up to 10 weeks into a pregnancy. Following your dosing schedule is very important for this medication to be effective. Try not to miss any doses.

Endometrin comes with patient instructions for safe and effective use. Follow these directions carefully. Ask your doctor or pharmacist if you have any questions.

Endometrin can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert.

Before using Endometrin
You should not use Endometrin if you have ever had an allergic reaction to it, or if you have:
a history of stroke, blood clot, or circulation problems;
breast or uterine cancer;
abnormal vaginal bleeding;
liver disease; or
if you have recently had a tubal pregnancy or an incomplete or "missed" abortion.

Before using Endometrin, tell your doctor if you have any of the following conditions. You may need a dose adjustment or special tests to safely use progesterone:
high blood pressure, heart disease, congestive heart failure;
migraines,
asthma;
kidney disease;
seizures or epilepsy;
diabetes; or
a history of depression.

Do not use Endometrin without your doctor's consent if you are pregnant, unless you are using the medication as part of your fertility treatment. Endometrin can pass into breast milk and may harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

How should I use Endometrin?
Use Endometrin exactly as it was prescribed for you. Do not use larger amounts, or use it for longer than recommended by your doctor. Follow the directions on your prescription label.

When used as part of fertility treatment, Endometrin may be given for up to 10 weeks into a pregnancy. Following your dosing schedule is very important for this medication to be effective. Try not to miss any doses.

Endometrin comes with patient instructions for safe and effective use. Follow these directions carefully. Ask your doctor or pharmacist if you have any questions.

Do not use other vaginal medications within 6 hours before or after using Endometrin. Use only vaginal products that your doctor has recommended. Store Endometrin at room temperature away from moisture and heat. Follow the instructions provided with your medication.

What happens if I miss a dose?
Use the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and use the medicine at the next regularly scheduled time. Do not use extra medicine to make up the missed dose.

Call your doctor if you miss more than one dose of Endometrin.

What happens if I overdose?
Seek emergency medical attention if you think you have used too much of this medicine. Symptoms of a Endometrin overdose are not known.

What should I avoid while using Endometrin?
Progesterone can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert.

Endometrin side effects
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Call your doctor at once if you have any of these serious side effects:
sudden headache, numbness or weakness (especially on one side of the body), shortness of breath, or problems with vision, speech, or balance;
chest pain or heavy feeling, pain spreading to the arm or shoulder;
pain or swelling in one or both legs;
nausea, stomach pain, low fever, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes);
swelling in your hands, ankles, or feet;
fever, chills, body aches, flu symptoms;
a breast lump; or
symptoms of depression (sleep problems, weakness, mood changes).
Less serious side effects may include:
mild nausea, vomiting, bloating, stomach cramps;
diarrhea, constipation, bloating;
dizziness, drowsiness, tired feeling;
pain in your vaginal or rectal area;
pain during intercourse;
loss of interest in sex;
breast pain, swelling, or tenderness;
joint or muscle pain;
increased night-time urination; or
vaginal itching, burning, or discharge.
This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect Endometrin?
There may be other drugs that can interact with Endometrin. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.

Where can I get more information?
Your pharmacist can provide more information about progesterone.
Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners.

The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

责任编辑:admin


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