通用名称为MEBARAL
Mephobarbital 32mg +（1 / 2粒），50毫克（3 / 4粒），100毫克（1.5粒）;标签; +得分。

法律分类：
CIV

药理班级MEBARAL
巴比妥类。

制造商MEBARAL
Lundbeck公司公司
适应症MEBARAL
对于大发作和小发作癫痫的治疗。

成人剂量为MEBARAL
主动与小剂量，增加超过4或5天逐渐增强。正常范围：400毫克，每日600mg。同时服用苯巴比妥：剂量应每半量单独使用。同时服用苯妥英：降低苯妥英钠的剂量，但剂量给予充分的mephobarbital。肾或肝功能不全，老年人，体弱：减少剂量。

儿童剂量为MEBARAL
<5yrs：16 - 32mg每日3〜4倍。 ≥5yrs：32 - 64mg每日3〜4倍。

禁忌的MEBARAL
舱单或潜在卟啉症。

警告/注意事项为MEBARAL
肝昏迷先兆症状：不推荐。受损肝，肾，心脏，呼吸功能。重症肌无力。粘液性水肿。维生素。 D缺乏症。急性或慢性疼痛。抑郁症。自杀倾向。药物或酒精滥用。监测造血，长期治疗肾，肝系统。避免突然停止。写出最小的实际金额℞。老人。虚弱。劳动和交付。妊娠（部件D）;可能引起胎儿损害。护理母亲。

相互作用的MEBARAL
避免伴随灰黄霉素。五月对抗口服抗凝血剂（如华法林），皮质类固醇（可能需要调整剂量），强力霉素（显示器），口服避孕药（考虑其他的避孕方法）。可能是potentiated由丙戊酸钠，丙戊酸，单胺氧化抑制剂。添加剂中枢神经系统抑制作用用酒精，镇静剂等中枢神经系统。同时服用苯妥英：经常监测血药浓度。

为MEBARAL不良反应
嗜睡，情绪激动，精神错乱，hyperkinesia，运动失调，中枢神经系统抑郁，做恶梦，精神紧张，精神紊乱，幻觉，失眠，焦虑，头晕，思维异常，通气不足，呼吸暂停，心动过缓，低血压，晕厥，胃肠不适，便秘，头痛，过敏反应，发烧，肝功能损害，巨幼细胞性贫血（长期使用）。

如何MEBARAL提供？
标签- 250

MEBARAL（Mephobarbital）

Generic Name for MEBARAL

Mephobarbital 32mg+ (1/2 grain), 50mg (3/4 grain), 100mg (1½ grain); tabs; +scored.

Legal Classification:

CIV

Pharmacological Class for MEBARAL

Barbiturate.

Manufacturer of MEBARAL

Lundbeck Inc.

Indications for MEBARAL

For the treatment of grand mal and petit mal epilepsy.

Adult dose for MEBARAL

Initiate with small dose and increase gradually over 4 or 5 days. Usual range: 400mg–600mg daily. Concomitant phenobarbital: dose should be ½ the amount of each used alone. Concomitant phenytoin: reduce dose of phenytoin but give full dose of mephobarbital. Renal or hepatic impairment, elderly, debilitated: reduce dose.

Children's dosing for MEBARAL

<5yrs: 16–32mg 3 or 4 times daily. ≥5yrs: 32–64mg 3 or 4 times daily.

Contraindications for MEBARAL

Manifest or latent porphyria.

Warnings/Precautions for MEBARAL

Premonitory signs of hepatic coma: not recommended. Impaired hepatic, renal, cardiac, respiratory function. Myasthenia gravis. Myxedema. Vit. D deficiency. Acute or chronic pain. Depression. Suicidal tendencies. Drug or alcohol abuse. Monitor hematopoietic, renal, hepatic systems with long-term therapy. Avoid abrupt cessation. Write ℞ for smallest practical amount. Elderly. Debilitated. Labor & delivery. Pregnancy (Cat. D); may cause fetal damage. Nursing mothers.

Interactions for MEBARAL

Avoid concomitant griseofulvin. May antagonize oral anticoagulants (eg, warfarin), corticosteroids (may require dosage adjustments), doxycycline (monitor), oral contraceptives (consider alternative contraceptive method). May be potentiated by sodium valproate, valproic acid, MAOIs. Additive CNS depressant effects with alcohol, other CNS depressants. Concomitant phenytoin: monitor blood levels frequently.

Adverse Reactions for MEBARAL

Somnolence, agitation, confusion, hyperkinesia, ataxia, CNS depression, nightmares, nervousness, psychiatric disturbance, hallucination, insomnia, anxiety, dizziness, abnormal thinking, hypoventilation, apnea, bradycardia, hypotension, syncope, GI upset, constipation, headache, hypersensitivity reactions, fever, liver damage, megaloblastic anemia (chronic use).

How is MEBARAL supplied?

Tabs—250