通用名称为LASTACAFT
Alcaftadine 0.25％; OPH soln;含有苯扎氯铵。

法律分类：
接收

药理班级LASTACAFT
抗组胺/肥大细胞稳定剂。

制造商LASTACAFT
AllerganIndications为LASTACAFT
预防过敏性结膜炎相关的眼部瘙痒。

成人和儿童：
<2yrs：不推荐。 ≥2yrs：1，在每只眼睛滴，每日一次。

警告/注意事项为LASTACAFT
隐形眼镜（删除;可能重新插入给药后10分钟，如果眼睛不红）。妊娠（Cat.B）。护理母亲。

为LASTACAFT不良反应
眼效果（如刺痛，烧灼/刺痛，发红，瘙痒），鼻咽炎，头痛，流感。

如何LASTACAFT提供？
Soln - 3ML

药物名称：阿卡他定滴眼液[Lastacaft (alcaftadine ophthalmic solution)]
适应症：瘙痒与红眼病
公司：强生，Allergan
批准日期：2010年7月28日
药品类型：小分子药物
简要说明：用于预防2岁及以上变应性结膜炎患者的眼痒。阿卡他定属组胺H1-受体拮抗剂和肥大细胞稳定剂,是经抑制肥大细胞释放组胺并阻止组胺作用而呈现药效的。Lastacaft为一日1次用药,推荐剂量方案是每日每眼滴1滴药液。

INDICATIONS AND USAGE
LASTACAFT™ is an H1 histamine receptor antagonist indicated for the prevention of itching associated with allergic conjunctivitis.

MECHANISM OF ACTION
Alcaftadine is an H1 histamine receptor antagonist and inhibitor of the release of histamine from mast cells. Decreased chemotaxis and inhibition of eosinophil activation have also been demonstrated.

IMPORTANT SAFETY INFORMATION

WARNINGS AND PRECAUTIONS
To minimize contaminating the dropper tip and solution, care should be taken not to touch the eyelids or surrounding areas with the dropper tip of the bottle. Keep bottle tightly closed when not in use.

Patients should be advised not to wear a contact lens if their eye is red.

LASTACAFT™ should not be used to treat contact lens-related irritation.

Remove contact lenses prior to instillation of LASTACAFT™. The preservative in LASTACAFT™, benzalkonium chloride, may be absorbed by soft contact lenses. Lenses may be reinserted after 10 minutes following administration of LASTACAFT™.

LASTACAFT™ is for topical ophthalmic use only.

ADVERSE REACTIONS
The most frequent ocular adverse reactions, occurring in < 4% of LASTACAFT™ treated eyes, were eye irritation, burning and/or stinging upon instillation, eye redness, and eye pruritus.

The most frequent non-ocular adverse reactions, occurring in < 3% of subjects with LASTACAFT™ treated eyes, were nasopharyngitis, headache, and influenza. Some of these events were similar to the underlying disease being studied.

Generic Name for LASTACAFT

Alcaftadine 0.25%; oph soln; contains benzalkonium chloride.

Legal Classification:

Rx

Pharmacological Class for LASTACAFT

Antihistamine/mast cell stabilizer.

Manufacturer of LASTACAFT

Allergan

Indications for LASTACAFT

Prevention of ocular itching associated with allergic conjunctivitis.

Adults and Children:

<2yrs: not recommended. ≥2yrs: 1 drop in each eye once daily.

Warnings/Precautions for LASTACAFT

Contact lenses (remove; may reinsert 10 minutes after administration, if eye is not red). Pregnancy (Cat.B). Nursing mothers.

Adverse Reactions for LASTACAFT

Ocular effects (eg, irritation, burning/stinging, redness, pruritus), nasopharyngitis, headache, influenza.

How is LASTACAFT supplied?

Soln—3mL