【中文品名】洛曲松
【药效类别】抗真菌药>复方
【通用药名】LOTRISONE
【别　　名】克霉唑/倍他米松, Clotrimazole/Betamethasone, Lotricamb, Lotriderm
【化学名称】 Pregna-1,4-diene-3,20-dione, 9-fluoro-11-hydroxy-16-methyl-17,21-bis(1-oxopropoxy)-, (11β,16β)-. mixt. with 1-[(2-Chlorophenyl)diphenylmethyl]-1H-imidazole
【CA登记号】[92522-91-3]
【结 构 式】

【分 子 式】
【分 子 量】
【收录药典】
【开发单位】先令-普劳(Essex)
【首次上市】
【性　　状】
【用　　途】
一种由克霉唑（1%）和倍他米松二丙酸酯（0.05%）的复方制剂，用于治疗各种伴有炎症的真菌性皮肤病。

【原产地英文商品名】LOTRISONE 30mls Lotion
【原产地英文药品名】CLOTRIMAZOLE/BETAMETHASONE DIPROPIONATE
【中文参考商品译名】
注：以下产品不同规格和不同价格，购买时请以电话咨询为准！
·LOTRISONE 30毫升洗剂
·LOTRISONE 45克乳膏剂
【中文参考药品译名】克霉唑/倍他米松二丙
【生产厂家中文参考译名】先灵
【生产厂家英文名】SCHERING

What is Lotrisone?

Clotrimazole is an antifungal antibiotic that treats or prevents infection caused by fungus.

Betamethasone is a topical steroid that reduces itching, swelling, and redness of the skin.

The combination of betamethasone and clotrimazole is used to treat fungal skin infections such as athletes foot, jock itch, and ringworm.

Lotrisone may also be used for other purposes not listed in this medication guide.

What is the most important information I should know about Lotrisone?

Do not cover treated skin areas with a bandage or tight clothing, unless your doctor has told you to. Do not use this medication on a child younger than 17 years old. Children are more likely to absorb the steroid through the skin. Never use Lotrisone to treat diaper rash. It may take up to 1 or 2 weeks of using Lotrisone before your symptoms improve. For best results, keep using the medication as directed. Talk with your doctor if your groin symptoms do not improve after 1 week, or if your foot symptoms do not improve after 2 weeks of treatment.

What should I discuss with my healthcare provider before using Lotrisone?

Do not use this Lotrisone if you have ever had an allergic reaction to:

·betamethasone (such as Betaderm, Diprolene, Luxiq, Taclonex, Uticort, Valisone);

·clotrimazole (such as Desenex, Lotrimin, Mycelex);

·other topical steroid medications such as alclometasone (Aclovate), clobetasol (Olux, Temovate), desonide (Desowen), desoximetasone (Topicort), diflorasone (Florone, Psorcon), fluocinolone (Capex, Dermotic, Fluonid, Fluorosyn, Synalar), fluocinonide (Dermacin, Lidex), fluticasone (Cutivate), halcinonide (Halog), halobetasol (Ultravate), mometasone (Elocon), triamcinolone (Aristocort, Kenalog); or

·other topical antibiotics such as econazole (Spectazole), ketoconazole (Kuric, Nizoral), miconazole (Cruex, Desenex, Fungoid, Lotrimin, Micatin, Monistat), sertaconazole (Ertaczo), or sulconazole (Exelderm).

Before using Lotrisone, tell your doctor if you are allergic to any drugs, or if you have any type of skin infection. You may not be able to use this medication, or you may need a dose adjustment or special tests during treatment.

FDA pregnancy category C. Lotrisone may be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment. It is not known whether Lotrisone passes into breast milk or if it could harm a nursing baby. Do not use Lotrisone without telling your doctor if you are breast-feeding a baby. Do not use Lotrisone on a child younger than 17 years old. Children are more likely to absorb the steroid through the skin. Never use Lotrisone to treat diaper rash.

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How should I use Lotrisone?

Use this medication exactly as it was prescribed for you. Do not use the medication in larger amounts, or use it for longer than recommended by your doctor. Follow the instructions on your prescription label.

This medication comes with patient instructions for safe and effective use. Follow these directions carefully. Ask your doctor or pharmacist if you have any questions.

Wash your hands before and after applying Lotrisone. Shake the lotion form of Lotrisone well just before you use it.

Apply a thin layer of Lotrisone and rub it in completely.

Do not cover treated skin areas with a bandage or tight clothing, unless your doctor has told you to.

After applying Lotrisone, allow your skin to dry completely before dressing. Wear loose-fitting clothing while you are treating jock itch. If you are treating athletes foot, wear clean cotton socks and keep your feet as dry as possible.

Do not use Lotrisone for longer than 2 weeks for jock itch or 4 weeks for athletes foot, unless your doctor has told you to. It may take up to 1 or 2 weeks of using Lotrisone before your symptoms improve. For best results, keep using Lotrisone as directed. Talk with your doctor if your groin symptoms do not improve after 1 week, or if your foot symptoms do not improve after 2 weeks of treatment. Store Lotrisone at room temperature away from moisture and heat. Keep the tube or bottle capped and tightly closed when not in use.

What happens if I miss a dose?

Use the medication as soon as you remember the missed dose. If it is almost time for your next dose, skip the missed dose and use the medicine at your next regularly scheduled time. Do not use extra medicine to make up the missed dose.

What happens if I overdose?

Seek emergency medical attention if you think you have used too much of this medicine. An overdose of Lotrisone applied to the skin is not expected to produce life-threatening symptoms.

What should I avoid while using Lotrisone?

Avoid getting Lotrisone in your eyes, mouth, and nose, or on your lips. If it does get into any of these areas, wash with water. Do not use Lotrisone on sunburned, windburned, dry, chapped, irritated, or broken skin.

Avoid wearing tight-fitting clothing that doesnt allow air circulation. Until the infection is healed, wear clothing that is made of natural fibers such as cotton.

What are the possible side effects of Lotrisone?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Stop using Lotrisone and call your doctor at once if you have any of these serious side effects:

·swelling, redness, or any signs of new infection;

·severe burning or stinging of treated skin;

·weight gain, rounding of the face;

·increased thirst or hunger, urinating more than usual; or

·anxiety, depressed mood.

Less serious Lotrisone side effects may include:

·mild skin itching or irritation;

·dry skin;

·changes in skin color;

·acne;

·scarring or thinning of the skin.

This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect Lotrisone?

It is not likely that other drugs you take orally or inject will have an effect on topically applied Lotrisone. But many drugs can interact with each other. Tell your doctor about all your prescription and over-the-counter medications, vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start a new medication without telling your doctor.

What does Lotrisone look like?

Betamethasone and clotrimazole topical is available with a prescription under the brand name Lotrisone as a cream. Other brand or generic formulations may also be available. Ask your pharmacist any questions you have about this medication.

·Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

·Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the and therefore Multum does not warrant that uses outside of the are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.