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利巴韦林片|Copegus(Ribavirin Tablets)

2011-09-01 00:59:54  作者:新特药房  来源:互联网  浏览次数:511  文字大小:【】【】【
简介: 英文药名: Copegus (Ribavirin Tablets) 中文药名: 利巴韦林片 药品简介 利巴韦林又称为三氮唑核苷或病毒唑,是一种能抑制核酸合成的广谱抗病毒药。上世纪70年代我国仿制成功,目前已有多种剂型在临 ...
关键字:利巴韦林片|

英文药名: Copegus (Ribavirin Tablets)

中文药名: 利巴韦林片

药品简介

利巴韦林又称为三氮唑核苷或病毒唑,是一种能抑制核酸合成的广谱抗病毒药。上世纪70年代我国仿制成功,目前已有多种剂型在临床使用。该药由于疗效确切,毒副作用较低,已被列入国家医保甲类药品。利巴韦林在国内主要用于儿科、传染科和呼吸科等领域,其中,传染科主要用于治疗流行性出血热和慢性丙型肝炎。目前,美国FDA批准的利巴韦林制剂包括口服制剂和雾化吸入剂,其中,口服剂型(片剂、胶囊、口服液)的适应证是:与重组干扰素α联合用于治疗3岁和3岁以上未曾使用α干扰素治疗过的代偿性肝病,或18岁和18岁以上使用α干扰素治疗复发患者的慢性丙型肝炎。


通用名:利巴韦林

商品名称:COPEGUS ®片剂,200 mg

主治:
COPEGUS ®是用于提高组合与聚乙二醇干扰素α- 2a(基因重组)治疗以下慢性丙型肝炎病毒血症之一
1。在血清型1例(基因型我(1A)或II(1B))具有较高的HCV - RNA的负载
2。非应答或relapsers与干扰素单药治疗

用法用量:
COPEGUS ®应结合使用聚乙二醇干扰素α- 2a(基因重组)。
通常情况下,为成人剂量,利巴韦林口服按照以下剂量。 COPEGUS ®管理,在考虑病人的条件,应采取适当措施,如用量减少和停止。

Bodyweight

   Daily dosage    

       After breakfast       

       After dinner      

=< 60kg

600 mg

200 mg

400 mg

  60kg >, =< 80kg  

800 mg

400 mg

400 mg

> 80 kg

1000 mg

400 mg

600 mg

 
Copegus

Copegus Information

Copegus is known to fight viruses in the body though the exact way it works remains to be unknown.

Copegus Indications

Copegus when combined with Interferon alfa product is used treating chronic hepatitis C. It is used in patients with liver disease who have not been previously treated with Interferon alfa or those who have relapses from alfa Interferon therapy. Copegus may also be used for purposes other than those stated here.

Copegus Warnings

Copegus may not be advisable if you have any of the following:

  • History of heart disease
  • Hemoglobin disorder such as anemia, thalassemia, or sickle-cell anemia
  • Pancreatitis
  • Kidney problems
  • Mental problems
  • History of organ transplant
  • Thyroid disease
  • History of alcoholism or drug abuse
  • Cancer
  • Infection of hepatitis B or HIV and AIDS
  • Diabetes
  • Past Interferon treatment of hepatitis C that did not work

If you have any of these conditions, your doctor may not allow you to take Copegus, may need to adjust your dosage or may need to monitor your intake of the drug.

Copegus belongs to the FDA pregnancy Category X, which means that is known to cause abnormalities to an unborn baby. Do no take this drug when you are pregnant or planning to be pregnant. Male partners of pregnant women should also not use this drug. It is yet unknown whether this drug passes into breast milk but do not take this drug when breast-feeding an infant for it may harm a nursing baby.

Older people are at a higher risk for side effects. Patients over 65 years may need lower dosage than younger people.

Copegus Intake Guidelines

Copegus should be taken in exactly as instructed by your doctor. If there are matters that you do not understand, ask your doctor, nurse or pharmacist to explain those matters to you.

Each tablet or capsule of this drug should be taken in with a full glass of water and should be taken in with an Interferon alfa product.

To prevent dehydration, one should maintain adequate fluid intake. It is essential to follow your normal dosing schedule and your dosing instructions.

To get the maximum benefit of this product, take it regularly.

Copegus Dosage

Dosage of Copegus should be obtained from your doctor. Dosage may vary from person to person with regards to a variety of factors.

Copegus Overdose

Symptoms of overdose for Copegus are not yet known. Seek immediate medical attention if you suspect overdose.

Copegus Missed Dose

If possible, do not miss a dose of this product. If a dose is missed, take it as soon as remembered on the same day. If more than a day has elapsed, refer to your doctor as to what to do. Do not take a double dose of this medication unless otherwise directed by your doctor.

Copegus Side Effects

Copegus may serious side effects and allergic reactions, which include:

  • Difficulty in breathing
  • Closing of the throat
  • Swelling of the face, lips or tongue
  • Hives
  • Chest, arm or neck pain
  • Trouble in breathing or increased cough
  • Severe stomach pain or lower back pain
  • Bloody stools
  • Unusual bruising or bleeding
  • Changes in vision
  • Fever greater than 100.5 degrees Fahrenheit
  • Psoriasis

Discontinue taking Copegus and inform your doctor immediately if you experience any of the preceding symptoms.

Copegus may cause anemia, which may be dangerous for patients who have heart or circulatory problems. Copegus along with Interferon alfa may cause depression, suicidal behavior and psychosis. Talk to your doctor if you experience mental problems.

Copegus also has side effects, which are less serious and more likely to occur. They include:

  • Fatigue or tiredness
  • Nausea or decreased appetite
  • Thinning of the hair
  • Rash or itching
  • Insomnia or restlessness

Continue taking Copegus but inform your doctor immediately if you experience any of the following symptoms.

Other side effects may also occur when you take Copegus. Inform your doctor if you experience anything unusual while or after taking this drug.

Copegus Drug Reactions

Other drugs may react with Copegus. Inform your doctor if you are taking drugs other than Copegus including over the counter prescriptions such as vitamins, minerals, and herbal products.

In some countries COPEGUS may also be known as: Laztie, Vibuzol, Xilopar, Virazide, Rebetol, Ribaviron C, Viramid, RibaPak, Ribaspheres

责任编辑:admin


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