英文药名: Cloderm(Clocortolone Pivalate)
中文药名: 氯可托龙匹伐酸酯霜
药品简介
用于治疗包括特应性皮炎、脂溢性皮炎和接触性皮炎在内皮肤病的炎症和瘙痒。
临床发现,本品治疗4日即快速起效。纳入297例接触性皮炎、特应性皮炎和皮脂溢性皮炎患者的双盲安慰剂对照临床研究显示,本品治疗7日,60%的患者疗效非常好;治疗21日内,87%患者疗效非常好。
新戊酸氯可托龙乳膏是可能造成皮肤过敏反应最小的中强度糖皮质激素。在其它临床研究中验证,本品与其它糖皮质激素无显著的交叉反应。
本品最常见的不良反应是皮肤干燥、刺激、滤泡炎、形成痤疮和灼热。
Generic Name for CLODERM
Clocortolone pivalate 0.1%; crm; contains parabens.
Legal Classification:
Rx
Manufacturer of CLODERM
Valeant Pharmaceuticals, Inc
Indications for CLODERM
Corticosteroid-responsive dermatoses.
Adults and Children:
Apply thin film three times daily.
Contraindications for CLODERM
Do not use superpotent forms on face, groin, or axillae. Exclude viral disease (eg, chickenpox, measles).
Warnings/Precautions for CLODERM
Treat infection if present; discontinue if infection persists or worsens. Do not use near eyes, or on diaper dermatitis or pre-existing skin atrophy. Do not use fluorinated steroids longer than 1 week on the face. Avoid abrupt cessation in chronic use. Systemic absorption increased by broken or inflamed skin, prolonged use, application to large surface area, or use of occlusive dressings. Occlude only if necessary; do not occlude higher potency products. Monitor adrenal function in children if a high potency product or occlusion is used, and in adults if more than 50g weekly of a high potency product is used. Discontinue or reduce dose or potency if HPA axis suppression, Cushing's syndrome, hyperglycemia, glucosuria, or irritation occurs. Use lowest effective dose and potency (esp. in children). Use caution if applying to face or body folds. Do not use continuously or for prophylaxis. Foams are flammable. Reevaluate periodically. Pregnancy (Cat.C). Nursing mothers.
Adverse Reactions for CLODERM
Burning, stinging, pruritus, erythema, skin atrophy, striae, miliaria, secondary infections, hypopigmentation, folliculitis, hypertrichosis, acneiform eruptions, dermal cracking and fissuring, telangiectasia, contact dermatitis, other local effects, immunosuppression, masks infections, HPA axis suppression (esp. in children).
How is CLODERM supplied?
Crm—15g, 45g, 90g
Pump—30g
Related Disease:
Dermatitis~topical steroids