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Child Care products (Novamox-125)
Novamox-125
Composition
Novamox 125
Each dispersible uncoated tablet contains ....
Amoxycillin Trihydrate IP equivalent to Amoxycillin 125 mg
Description
Amoxycillin is a semi synthetic penicillin which exerts its bactericidal action by inhibition of cell wall synthesis. It acts against a broad spectrum of gram positive and gram negative microorganisms.
Indications
RESPIRATORY TRACT INFECTIONS
GENITO URINARY TRACT INFECTIONS
SKIN AND SOFT TISSUE INFECTIONS
ENTERIC INFECTIONS
Bacterial diarrhoea, bacillary dysentery, shigellosis, salmonellosis, typhoid and paratyphoid fevers and carriers, cholecystitis and cholangitis.
DENTAL INFECTIONS
Post oro surgical and periodontal procedures.
Dosage and Administration
In all infections except gonorrhoea
Adults and children 20 kgs or more
250 500 mg thrice daily at equal intervals.
Children under 20 kgs
20-40 mg/kg/day eight hourly in divided doses.
Gonorrhoea
Single dose of 3 grams.
In impaired renal function
Dosage adjustments are required for patients with renal impairment or for patients undergoing haemodialysis.
A dose of 250 500 mg every 16 24 hours is suggested for adults with creatinine clearance less than 30 ml/minute.
A supplementary dose of 250 mg after every dialysis and maintenance dose of 250 500 mg every 16 24 hours is suggested for patients undergoing haemodialysis.
Contraindications
Hypersensitivity reactions to penicillins.
Warnings and Precautions
DRUG INTERACTIONS
Allopurinol: A significant increase in skin rashes is observed when allopurinol and ampicillin are given concurrently. A similar interaction can occur with amoxycillin.
Bacteriostatic drugs like chloramphenicol, erythromycin and tetracyclines may reduce the bactericidal action of amoxycillin.
PREGNANCY
The drug can be used safely throughout pregnancy at the normal adult doses.
NURSING MOTHERS
Amoxycillin is secreted into breast milk in small amounts. The potential risk is for sensitisation and skin rash in the child.
Side Effects
As with penicillins, adverse reactions to amoxycillin are generally those related to allergic response. These are more common in patients with a previous history of penicillin allergy or asthma, hay fever or urticaria. Reversible hyperactivity, agitation, anxiety, insomnia, confusion, behavioural changes and dizziness have been reported rare
Presentation
Novamox 125 ………Strip of 15 tablets
novamox-125
组成
novamox 125
每个分散的无涂层平板包含....
羟氨苄青霉素三水IP相当于阿莫西林125毫克
描述
阿莫西林是一种半合成青霉素，发挥其杀菌作用，通过抑制细胞壁的合成。针对革兰氏阳性和革兰氏阴性菌的广谱作用。
主治
呼吸道感染
泌尿生殖道感染
皮肤和软组织感染
肠道感染
细菌性腹泻，痢疾杆菌，志贺氏菌病，沙门氏菌病，伤寒和副伤寒和运营商，胆囊炎，胆管炎。
牙齿感染
发表奥罗手术和牙周程序。
剂量和给药方法
在所有的除外淋病感染
20公斤或以上的成人和儿童
250 500毫克，每日三次在相同的时间间隔。
20公斤以下的儿童
分次服用每小时20-40毫克/千克/天八。
淋病
单剂量3克。
在肾功能受损
患者肾功能不全或血液透析患者需要调整剂量。
250 500毫克剂量每16个24小时肌酐清除率小于30毫升/分钟的成人建议。
一个补充剂量为250毫克每250 500毫克每16个24小时的透析和维持剂量后，建议对血液透析病人。
禁忌
对青霉素的过敏反应。
警告和注意事项
药物相互作用
别嘌呤醇：观察皮疹的一个显着增加，同时给予时，别嘌呤醇及氨苄青霉素。类似的相互作用可发生阿莫西林。
抑菌药物，如氯霉素，红霉素和四环素可减少阿莫西林杀菌作用。
妊娠
该药物可用于整个孕期安全，在正常成人的剂量。
哺乳的母亲
阿莫西林分泌到母乳中少量的牛奶。潜在的风险是儿童的宣传和皮疹。
副作用
至于青霉素，阿莫西林不良反应通常是那些过敏性反应有关。这些都是在以前的历史与青霉素过敏或哮喘，枯草热或荨麻疹患者更常见。可逆的多动，情绪激动，焦虑，失眠，精神错乱，行为改变和眩晕已少见报道 | 
