部分中文亚莫利信息资料（仅供参考）
【药品名称】
通用名：格列美脲片(亚莫利)
英文名：Glimepiride Tablets
汉语拼音：Geliemeiniao Pian
本品主要成份为：格列美脲。其化学名称为：1-[4-[2-(3-乙基-4-甲基-2-氧代-3-吡咯啉-1-甲酰胺基)-乙基]-苯磺酰]-3-(反式-4-甲基环己基)-脲。
【性状】本品为白色片。
【作用机理】本品为第三代磺酰脲类口服降血糖药，其降血糖作用的主要机理是刺激胰岛B细胞分泌胰岛素，同时提高周围组织对胰岛素的敏感性。这就是亚莫利的双重作用机制。本品与胰岛素受体结合及解离的速度较格列本脲为快，较少引起较重低血糖。
【药代动力学】本品口服后迅速而完全吸收，空腹或进食时服用对本品的吸收无明显影响，服后2～3小时达血药峰值，口服4mg平均峰值约为300ng/ml，t1/2约5～8小时。但因为生理性的缓释作用，所以每天只需服用一次。本品在肝脏内经P450氧化物代谢成无降糖活性的代谢物，60%经尿排泄，40%经粪便排泄。
【适应症】适用于食物、运动疗法及减轻体重均不能满意控制血糖的2型糖尿病。
【禁 忌】
1．对本品任何成份过敏者。
2．1型糖尿病、糖尿病昏迷、酮症酸中毒、严重的肾脏或肝功能损害，对格列美脲、其它磺脲类、磺胺类或赋形剂过敏者。
3．对于严重肾脏或肝功能损害的病人，应改用胰岛素治疗。
4．格列美脲片禁用于妊娠和哺乳病人。
【用法用量】
遵医嘱口服用药。对于糖尿病患者，格列美脲或任何其他降糖药物都无固定剂量，必须定期测量空腹血糖和糖化血红蛋白以确定患者用药的最小有效剂量；测定糖化血红蛋白水平以监测患者的治疗效果。
通常起始剂量：在初期治疗阶段，格列美脲的起始剂量为1～2mg，每天一次，早餐时或第一次主餐时给药。那些对降糖药敏感的患者应以1mg每天一次开始，且应谨慎调整剂量。格列美脲与其他口服降糖药之间不存在精确的剂量关系。格列美脲最大初始剂量不超过2mg。
通常维持剂量：通常维持剂量是1～4mg每天一次，推荐的最大维持量是8mg每天一次。剂量达到2mg后，剂量的增加根据患者的血糖变化，每1～2周剂量上调不超过2mg。
Common uses
This medicine is a sulfonylurea used to treat diabetes mellitus (sugar diabetes).
Before using
Additional monitoring of your dose or condition may be needed if you are taking chloramphenicol, dexfenfluramine, fenfluramine, gemfibrozil, monoamine oxidase inhibitors (maois), oxyphenbutazone, phenylbutazone, sulfa antibiotics, certain "water pills" (diuretics such as hydrochlorothiazide), or medicine for high blood pressure or heart conditions (ace inhibitors). Inform your doctor of any other medical conditions, allergies, pregnancy, or breast-feeding.
Use of this medicine is not recommended if you have a history of acidosis. Contact your doctor or pharmacist if you have any questions or concerns about taking this medicine.
Directions
Follow the directions for using this medicine provided by your doctor. Take this medicine with breakfast or your first main meal.
Store this medicine at room temperature in a tightly-closed container, away from heat and light. If you miss a dose of this medicine, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.
Cautions
Before you begin taking any new medicine, either prescription or over-the-counter, check with your doctor or pharmacist. Do not exceed the recommended dose without checking with your doctor.
Follow the dietary plan provided by your doctor. This medicine may cause increased sensitivity to the sun. Avoid exposure to the sun, sunlamps, or tanning booths until you know how you react to this medicine. Use a sunscreen or protective clothing if you must be outside for a prolonged period. Do not drink alcohol without first discussing it with your doctor.
This medicine may cause hypoglycemia (low blood sugar). Signs of hypoglycemia include an increased heart rate, headache, sweating, tremor, increased hunger, changes in vision, nervousness, or tiredness. Discuss with your doctor or nurse how to handle hypoglycemic reactions.
If you plan on becoming pregnant, discuss with your doctor the benefits and risks of using this medicine during pregnancy. It is unknown if this medicine is excreted in breast milk. Do not breast-feed while taking this medicine.
Possible side effects
Side effects, that may go away during treatment, include dizziness, weakness, headache, or nausea. If they continue or are bothersome, check with your doctor. If you notice other effects not listed above, contact your doctor, nurse, or pharmacist.
If you take too much
If overdose is suspected, contact your local poison control center or emergency room immediately. Symptoms of overdose may include lightheadedness, sweating, rapid pulse, tremor, confusion, seizures, and loss of consciousness.
Additional information
Do not share this medicine with others for whom it was not prescribed. Do not use this medicine for other health conditions.
Keep this medicine out of the reach of children. If using this medicine for an extended period of time, obtain refills before your supply runs out.
Drug interactions
Drug interactions can result in unwanted side effects or prevent a medicine from doing its job. Some medicines or medical conditions may interact with this medicine. Inform your doctor or pharmacist of all prescription and over-the-counter medicine that you are taking.

附件：

20096721473125.pdf    

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产地国家: 德国
原产地英文商品名:
AMARYL-4mg/Tablet,30Tablets
原产地英文药品名:
GLIMEPIRIDE
中文参考商品译名:
亚莫利-4毫克/片，30片/盒
中文参考药品译名:
格列美脲
生产厂家中文参考译名:
凯瑞特
生产厂家英文名:
Hoechst　AG
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产地国家: 德国
原产地英文商品名:
AMARYL-2mg/Tablet,30Tablets
原产地英文药品名:
GLIMEPIRIDE
中文参考商品译名:
亚莫利-2毫克/片，30片/盒
中文参考药品译名:
格列美脲
生产厂家中文参考译名:
凯瑞特
生产厂家英文名:
Hoechst　AG