英文药名:Avigan(Favipiravir TABLETS)
中文药名:法匹拉韦片
日文药名:アビガン錠
生产厂家:富山化学
药品介绍
新型RNA聚合酶抑制剂
批准时间:2014/03/24
欧洲商标名:Abigan®200毫克片剂
通用名称:Favipiravir
【适合病症】抗病毒剂。A型流感(包括禽流感和甲型H1N1流感感染)的治疗
【用法用量】一天两次,每次200mg-400mg,第五天每日两次口服一次,在5天累计给药周期。
【包装规格】200mg*100片/盒
アビガン錠(ファビピラビル(T-705))Avigan( Favipiravir )法匹拉韦片
Favipiravir was synthesized from 3-amino-2-pyrazinecarboxylic acid by esterification, bromination with NBS, diazotization and amination to give 6-bromo-3-hydroxypyrazine-2-carboxamide, which was subjected to chlorination with POCl3, fluorination with KF, and hydrolysis with an overall yield of about 22%.