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DIGOSIN Elixir(Digoxin)地高辛药剂

2016-03-26 08:30:17  作者:新特药房  来源:互联网  浏览次数:0  文字大小:【】【】【
简介:英文药名: DIGOSIN Elixir(Digoxin) 中文药名: 地高辛药剂 生产厂家:中外制药 ジゴシンエリキシル0.05mg/mL 治疗类别名称洋地黄苷制剂商標名 DIGOSIN一般名ジゴキシン(Digoxin)(JAN) 化学名3β‐[ ...

英文药名: DIGOSIN Elixir(Digoxin)

中文药名: 地高辛药剂

生产厂家:中外制药

ジゴシンエリキシル0.05mg/mL

治疗类别名称
洋地黄苷制剂
商標名
DIGOSIN
一般名
ジゴキシン(Digoxin)(JAN)
化学名
3β‐[2,6‐Dideoxy‐β‐D‐ ibo‐hexopyranosyl‐(1→4)‐2,6‐dideoxy‐β‐D‐ ibo‐hexopyranosyl‐(1→4)‐2,6‐dideoxy‐β‐D‐ ibo‐hexopyranosyloxy]‐12β,14‐dihydroxy‐5β,14β‐card‐20(22)‐enolide
構造式

分子式
C41H64O14
分子量
780.94
性 状
为无色至白色晶体或白色结晶粉末。
易溶于吡啶,乙醇(95)中微溶,在乙酸(100)极微溶,和几乎不溶于水。
适应证
适用于急性心力衰竭和慢性心力衰竭等。
用法用量
以原处方资料为准
药效药理
1.对心脏的影响
钙心脏衰竭中的利用效率降低状态结果的效率提高到由高辛正常水平,心作用展出。
2. 神经刺激的效果,通过在除了迷走神经反射等通过颈动脉窦(狗)抗交感神经作用导致心动过缓。
3. 刺激传导速度的抑制,将指示由扩展(狗)或类似的不应期的作用的抗心律失常作用。
包装规格
0.05mg/mL*100毫升(棕瓶)
生产厂商
中外制药有限公司


注:使用以原处方为准:http://www.info.pmda.go.jp/go/pack/2113004S1033_1_05/
DIGOSIN Elixir 0.05mg/mL(ジゴシンエリキシル0.05mg/mL) 
Brand name : DIGOSIN Elixir 0.05mg/mL
 Active ingredient: Digoxin
 Dosage form: translucent (light) turquoise solution
 Print on wrapping: 
Effects of this medicine
This medicine works on heart directly to strengthen myocardial contractile force and to adjust excessively fast pulse. It is usually used to prevent and treat cardiac failure and various kinds of tachycardia as well as to treat congestive cardiac failure, fast pulse caused by atrial fibrillation and atrial flutter, and paroxysmal supraventricular tachycardia.
Before using this medicine, be sure to tell your doctor and pharmacist
•If you have previously experienced any allergic reaction (itch, rash etc.) to any medicines.
If you are a patient with atrioventricular block, sinoatrial block, digitalism, obstructive myocardiopathy, acute myocardial infarction, premature ventricular contraction, pericarditis, cor pulmonale, WPW syndrome, electrolyte abnormality (hypokalemia, hypercalcemia, hypomagnesemia, etc.), renal disease, hypothyroidism, or hyperthyroidism.
If you are a patient on hemodialysis or alcoholism treatment.
•If you are pregnant or breastfeeding.
•If you are taking any other medicinal products. (Some medicines may interact to enhance or diminish medicinal effects. Beware of over-the-counter medicines and dietary supplements as well as other prescription medicines.)
Dosing schedule (How to take this medicine)
•Your dosing schedule prescribed by your doctor is <<to be written by a healthcare professional>>
•For adults: In the case of rapid saturation method [saturation dosage: 20-80mL (1.0-4.0mg of the active ingredient)], in general, take 10-20mL (0.5-1.0mg of the active ingredient) at the first and after that keep taking 10 mL (0.5mg of the active ingredient) at intervals of 6-8 hours until you get enough effectiveness from it. In the case of maintenance treatment, in general, take 5-10mL (0.25-0.5mg of the active ingredient) a day.
For children: In the case of rapid saturation method, in general, for children aged under 2, take 1.2-1.6mL/kg (0.06-0.08mg/kg of the active ingredient) in 3-4 divided doses a day. For children aged 2 or over, take 0.8-1.2mL/kg (0.04-0.06mg/kg of the active ingredient) in 3-4 divided doses a day. In the case of maintenance treatment, in general, take 1/5-1/3 of the saturating dosage.
Strictly follow the instructions in any case.
•The effect dose is very close to the toxic dose. The dosage should be adjusted according to your blood constitutes. Be sure to visit your doctor to check the blood constitutes periodically.
•If you missed a dose, skip the missed dose and continue your regular dosing schedule. If you have any questions, ask your doctor or pharmacist. However, you should never take two doses at one time.
•If you accidentally took more than your prescribed dose, consult with your doctor or pharmacist.
•Do not stop taking this medicine unless your doctor instructs you to do so.
Precautions while taking this medicine
•This medicine contains alcohol. Exercise caution to drive a car or operate dangerous machinery if you are especially sensitive to alcohol.
•Avoid taking hypericum perforatum (Saint John's wort)-containing food, since it affects this medicine.
Possible adverse reactions to this medicine
The most commonly reported adverse reactions include rash, urticaria, purpura, and edema. If any of these symptoms occur, consult with your doctor or pharmacist.
The symptoms described below are rarely seen as initial symptoms of the adverse reactions indicated in brackets. If any of these symptoms occur, stop taking this medicine and see your doctor immediately.
•very slow pulse, fast pulse, irregular heartbeat, disturbed pulse, shortness of breath, sudden loss of consciousness, chest constrictive feeling, chest pain. [digitalism (severe marked bradycardia, bigeminy, multifocal premature ventricular contraction, paroxysmal atrial tachycardia, atrioventricular block, ventricular tachycardia, arrhythmia such as ventricular fibrillation)]
•severe abdominal pain, bloody stool, fever, nausea, vomiting [non-occlusive mesenteric ischemia]
The above symptoms do not describe all the adverse reactions to this medicine. Consult with your doctor or pharmacist if you notice any symptoms of concern other than those listed above.
Storage conditions and other information
•Keep out of the reach of children. Tighten the cap and store at room temperature (1-30℃). Keep away from light and moisture.
•Discard the remainder. Do not store them. Ask the pharmacist or healthcare facility how to discard them.

责任编辑:admin


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