英文药名：Glucobay TAB（Acarbose） 中文药名：拜唐苹（阿卡波糖片） 生产厂家：拜耳制药日本公司 グルコバイ錠50mg／グルコバイ錠100mg Glucobay TAB（Acarbose）是一种新型口服降糖药 治疗类别名称 餐后高血糖改善剂 批准上市日期：1993年11月 商標名 Glucobay 50 Glucobay 100 構造式 一般名 アカルボース（Acarbose）JAN，（Acarbose INN） 化学名 O-4,6-Dideoxy-4-［［（1S,4R,5S,6S）-4,5,6-trihydroxy-3-（hydroxymethyl）-2-cyclohexene-1-yl］amino］-α-D-glucopyranosyl-（1→4）-O-α-D-glucopyranosyl-（1→4）-D-glucopyranose 分子式 C25H43NO18 分子量 645.60 性状 本品为白色粉末至浅黄色。 它是易溶于水，乙醇（95）微溶。 本产品是吸湿。 操作注意事项 强大的吸湿性存储在PTP板的状态。 药效药理 阿卡波糖的葡糖淀粉酶存在于小肠黏膜微绒毛膜，蔗糖酶，除了抑制麦芽糖酶的剂量依赖性，抑制胰液和唾液的α-淀粉酶，以抑制饭后血糖显著增加。 ● 碳水化合物（淀粉，麦芽糖，蔗糖等），以通过α-葡糖苷酶，葡萄糖在消化道抑制水解，通过直接抑制果糖的降解慢的碳水化合物的吸收。 ● 与改善餐后高血糖，以减少血糖的日变化的宽度，可以得到良好的血糖控制。 ● 由于抑制饭后增加血糖，它不会导致高胰岛素血症，因为胰岛素的上升被抑制。此外，由于有一个由这种药物对胰岛素分泌不直接作用，以减少胰腺β细胞的负担。 1. 对血糖水平的作用 ● 为50mg健康成人10例，100毫克，当一次200mg的单次口服用蔗糖，负荷后血糖上升一起，血清胰岛素增加是剂量依赖性抑制。 ● 如果你有50毫克，100毫克，并与膳食为200mg单剂量口服健康成人的7例，血糖升高的饭后，血清胰岛素升高是剂量依赖性地抑制。 ● 健康成人5例子100毫克21天随餐口服给药，一天三次，在在此期间进行的淀粉负荷试验的负荷后的增加血糖，血清胰岛素上升显著抑制。应当指出，没有观察到抑制诸如血糖上升的淀粉负荷试验的负载之前和之后施用给药结束后。 ● 每天在NIDDM病人100毫克12例，如果你三个月的时间口服与每次吃饭，空腹血糖三次被显著减少。 （注：此药的批准剂量为三次一次100毫克，每日1次） 2. 对血糖的昼夜节律变化的作用 如果有50毫克或100毫克两周口服每餐一天三次在NIDDM病人19例，血糖昼夜变化曲线向下运动时，血糖昼夜变化曲线区域下以剂量依赖的方式降低。 3.  对糖化血红蛋白的作用（HBA1） 每日三次，每次100毫克的NIDDM病人12例，如果你三个月的时间口服每餐，是HBA1减少显著。 适应病症 糖尿病（的餐后高血糖的改进但是，如果也通过饮食和运动治疗并不能提供足够的血糖控制，或在患者除了饮食和运动疗法所使用口服降血糖药或胰岛素制剂仅当不能获得足够的血糖控制）。 用法与用量 口服：由于个体间药效和耐受性的差异，应由医师确定各个患者服用的剂量。初始每天25～50mg，随后每周增加50mg至每次0.1～0.2g，每天3次，餐中服用，就餐时随第1～2口饭吞服。剂量可在1～2周后增加，也可根据需要，在以后的治疗过程中增加。最大推荐剂量为每次0.2g。严格控制饮食后，如果仍有不适症状，则剂量就不应再增加，而且如果需要还可降低一些。 包装规格 片剂 50毫克： PTP包装100片（10片×10），500片（10片×50）1050粒（片21×50） 100毫克：PTP包装100片（10片×10），500片（10片×50）1050粒（片21×50） 制造厂商 拜耳药品社有限公司 完整使用资料附件：http://www.info.pmda.go.jp/go/pack/3969003F1026_1_21/ Glucobay Diabetes remedy drug! Glucobai retards the decomposition to glucose which suppresses the rapid rise in blood glucose after meals and suppresses the rise in postprandial blood glucose level. <Ingredients> Acarbose 100 mg <Working> The sugar "blood sugar" in the blood is regulated by insulin / hormone secreted from the pancreas. Diabetes is a disease in which blood glucose levels rise because of insufficient insulin or poor workability. If left untouched, it causes various complications such as numbness of limbs (neuropathy), eye disease (retinopathy), kidney disease. This medicine suppresses the rapid rise in blood glucose after meals. Its action is slowly delaying the digestion and absorption of carbohydrate (sugar) from the intestine. It saves insulin secretion, so it will not strain the pancreas. Maintaining daily blood sugar levels properly will help prevent various complications that may occur in the future. <Remarks> In type 2 diabetes, diet therapy and exercise therapy are very important. The significance is also shown in the "Diabetes Prevention Program (DPP)" held in the United States. About 3,200 people (IGT) one step before diabetes, ① People who drink placebo (fake medicine) ② people who drink metformin as a drug for treating diabetes, ③ people who improve diet (strengthening diet / exercise therapy), and compared the prevention effect of the onset of diabetes. As a result of the examination, the most effective preventive effect was ③ "Group to improve eating habits" was. Type 2 diabetes and borderline people begin with diet therapy and exercise therapy. It is important to consult with a doctor or a nutritionist frequently, and keep it on a daily basis in a way that suits himself. If the blood sugar level drops sufficiently only with such basic therapy, you do not need to use medicine. However, when insufficient, medication by drinking medicine or insulin injection becomes necessary. Please try to keep basic therapy even if you start taking medicine. Apart from metformin, the final effect of drinking medicines (whether you can prevent heavy complications or live longer) has not always been ascertained. On the other hand, it is proved that controlling blood sugar more strictly with insulin injection drug can reduce heavy complications such as eye disease (retinopathy) and kidney disease. Even in type 2 diabetes, if you are recommended insulin therapy from a doctor, please accept it positively. ※ Please wait as it takes about several seconds to move to the next screen after clicking "Add to Cart" button. If you can not use the order form please contact us from here. We guarantee that all medicines and supplements handled by us are genuine. Please do not hesitate to apply because we are dealing directly with pharmaceutical exporters and distributors who officially possess a pharmaceutical export license. 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