喜疗妥概况
Hirudoid at a glance
Pharmacological characteristics, pharmacokinetics and bioavailability, insofar as this information is relevant to the therapeutic use of the product
药理学特性，药代动力学，生物药效学，药物应用相关信息
Pharmacological characteristics
药理学特性
Hirudoid/Hirudoid forte have local antithrombotic effects due to their influence on coagulation and fibrinolysis. In addition, they act as an anti-inflammatory based on their inhibitory effect on several inflammatory pathways.
喜疗妥乳膏/特强喜疗妥乳膏作用于机体血液凝固系统和纤维蛋白溶解系统而具有局部的抗血栓作用。另外，他们能通过抑制不同途径而具有抗炎作用。
Hirudoid/Hirudoid forte also promote the regeneration of connective tissue by activating the synthesis of mesenchymal cells and by normalizing the water-binding capacity of the intercellular substance.
喜疗妥乳膏/特强喜疗妥乳膏还能通过促进间叶细胞的合成以及恢复细胞间质保持水分的能力从而促进结缔组织的再生。
Thus, Hirudoid/Hirudoid forte prevent the formation of superficial thrombi, promote their absorption, counteract local inflammatory processes and accelerate the absorption of haematomas and the reduction of swelling.
因此，喜疗妥乳膏/特强喜疗妥乳膏能预防浅表血栓的形成，促进它们的吸收, 阻碍局部炎症的发展，加速血肿的吸收和具有消肿作用。
The products contribute to a regeneration of functional connective tissue structures.
喜疗妥乳膏/特强喜疗妥乳膏还能促进正常结缔组织的再生。
Pharmacokinetics, bioavailability
药代动力学，生物药效学
The active substance is absorbed from the cream and gel base through the skin into deeper tissue layers.In the organism a time-dependent partial depolymerization and a slight desulfatization occur.
乳膏和凝胶中的活性药物成分通过表皮吸收入更深的组织层。然后，在机体内随着时间的推移物质分解，发生部分的解聚和脱硫基。
Shelf life
有效期
5 years
5年
Date of information
信息日期
November 2001
Subject to modifications
2001 年11月修正
The text of this basic product information may differ from one country to another.
本产品手册的正文部分不同国家可能有所不同。
Hirudoid/Hirudoid forte have a cream and gel base, which promote diffusion and are extremely well tolerated. The preparations guarantee a fast and continuous absorption of the active ingredient MPS, thus ensuring a pronounced and long-lasting effect at the site of disorder.
喜疗妥乳膏/特强喜疗妥乳膏含有的乳膏和凝胶基质能促进药物的扩散吸收，并且具有非常良好的耐受性。 因而保证了活性药物成分－－多磺酸粘多糖的快速持续吸收,从而确保了药物能在患处发挥显著和持久的疗效。
Hirudoid/Hirudoid forte prevent the formation and enhance the dissolution of superficial thrombi and microthrombi.
喜疗妥乳膏/特强喜疗妥乳膏不但能预防浅表血栓和微血栓的形成而且能促进其分解。
Hirudoid/Hirudoid forte reduce swelling and inflammation.
喜疗妥乳膏/特强喜疗妥乳膏具有消肿和抗炎作用。
Hirudoid/Hirudoid forte promote the absorption of oedema and haematoma.
喜疗妥乳膏/特强喜疗妥乳膏能促进水肿和血肿的吸收。
Hirudoid/Hirudoid forte inhibit enzymes that cause tissue degeneration.
喜疗妥乳膏/特强喜疗妥乳膏能抑制导致组织分解代谢的酶。
Hirudoid/Hirudoid forte stimulates the production of proteoglycans and thereby promote tissue regeneration.
喜疗妥乳膏/特强喜疗妥乳膏能刺激蛋白多糖的生成，因而能促进组织再生。
Hirudoid/Hirudoid forte normalize the viscosity, permeability and water-binding capacity of the ground substance of the connective tissue.
喜疗妥乳膏/特强喜疗妥乳膏使结缔组织基质的粘性、渗透性和保持水分的能力恢复正常。
Hirudoid/Hirudoid forte have an excellent local and systemic tolerability, no influence on blood coagulation has been observed.
喜疗妥乳膏/特强喜疗妥乳膏具有极好的局部和系统耐受性，不影响机体血凝系统。
Efficacy and safety of Hirudoid/Hirudoid forte are documented in an extensive number of publications.
喜疗妥乳膏/特强喜疗妥乳膏的有效性和安全性已经在大量文献中被论证。
The preparations have been used successfully
in the treatment of superficial venous disorders, e.g. varicophlebitis, venous congestion, infusion and injection thrombophlebitis
in the follow-up treatment of phlebosclerosation
in the treatment of haematomas, contusions, distorsions
for the improvement of scar formation following injuries, operations and burns and for the softening of hard scar tissue.
喜疗妥乳膏/特强喜疗妥乳膏已经被成功地应用于
治疗浅表静脉疾病,如，曲张静脉炎，静脉栓塞，注射和输液引起的血栓性静脉炎；
静脉硬化的辅助治疗；
治疗血肿、擦伤和扭伤；
改善外伤、手术和烧伤之后的疤痕形成,并能软化疤痕。