喜疗妥有效治疗疤痕和早期受压区域
MPS has an activating influence on the connective tissue metabolism. This caused different authors to investigate whether scar tissue is also favourably influenced by MPS.
MPS能激活结缔组织代谢。因而许多作者研究了疤痕组织是否也会受其影响。
Schiedel reported on his experience of the treatment of hard scars with MPS. A clear softening and an increased flexibility of the tissue together with an improvement in blood flow led to good results.
Schiedel报道其用喜疗妥治疗硬化性疤痕的经验。结果显示疤痕组织显著软化、弹性和局部血流量增加。
In a double-blind study versus placebo, Shimizu et al. verified the influence of Hirudoid cream in 41 patients with hypertrophic scar formation. Hirudoid cream and placebo were applied once daily to a specific part of the scar and covered with a bandage. Parameters were the shade of color and hardness of the scar tissue, thickness and size of scar, and subjective symptoms.
在一安慰剂对照的双盲研究中，Shimizu等人验证了喜疗妥软膏对41位患者疤痕形成的影响。喜疗妥软膏一天一次涂抹于疤痕部位并用绷带覆盖。疗效评估参数为：疤痕组织的色泽和硬度，疤痕的厚度和大小以及主观症状。
Hirudoid cream was clinically superior in 76% of the cases investigated. In the other 24% of the patients no difference between the treatment groups was observed. The older the patients, the more the results were delayed. The prospects of success increased with an early start of treatment.
76％的病例显示喜疗妥的临床疗效优于安慰剂。另外24％的患者无组间差异。患者的年龄越大，起效时间越长。越早治疗，疗效越佳。
Hirudoid has been proven to significantly improve the metabolic situation in the early pressure areas when compared to placebo treatment.
经论证，对于早期受压区域代谢的改善，喜疗妥组显著优于安慰剂组。
In a double-blind, placebocontrolled study Kuisma/ Tamelander investigated the efficacy of Hirudoid cream in the prevention of pressure sores in geriatric patients. The presence of broken skin was an exclusion criterion. The creams were massaged in twice daily until complete subsiding of the symptoms or for a maximum of four weeks.
在一双盲、安慰剂对照的研究中，Kuisma和Tamelander观察了喜疗妥软膏对于老年患者压力性疼痛的预防作用。排除标准为表皮破损。软膏被一天两次轻轻地按摩入皮肤直至症状完全消失或最长四周。
Early pressure areas in 19 cases were evaluated in each group. With Hirudoid cream a significant size reduction, measured by planimetric evaluation of the affected areas, was observed during the 2nd week of treatment. At the end of the study 59% of Hirudoid patients were fully healed, which was significantly superior to the rate healed in the placebo group (p < 0.05).
每组共有19个病例，并对其早期受压区域进行了评估。通过对受累区域的测量评估显示，治疗两周末，其大小显著减小了。研究结束时，喜疗妥组的痊愈率为59%, 显著优于安慰剂组(p < 0.05)。