安体舒同时拥有国际、国内两项专利(国际专利号:C07D215/233,国内专利号:ZL 98 1 14407.1),表明安体舒的发明不仅得到了国内医学界的赞许,也得到了国际医学界的推崇,是中国医药科技在国际医学界的骄傲。
宫颈癌是妇女最常见的恶性肿瘤之一,它发生于宫颈的上皮组织。就目前治疗现状而言,宫颈癌仍是医学上未被攻克的一大难题。临床上,宫颈癌的治疗方法主要有手术切除、放疗、化疗以及中医药治疗。临床经验表明,宫颈癌单一的治疗方法有一定的局限性,目前为止,最佳的治疗方法是结合各种疗法的优点,进行宫颈癌的综合治疗如,靶向药物安体舒。
宫颈癌的综合治疗方案的选择,需要结合患者的病情状况以及身体机能等综合考虑。一般来说,早期宫颈癌癌肿较小,未发生扩散转移,其最为有效的治疗手段为手术切除,早期宫颈癌切除后的5年生存率可达60%左右,在手术之后最好一定时间内采取中医药治疗以防止复发,加快患者身体机能的恢复。若有残余病灶,可行放疗或化疗联合中医药治疗,以消灭残癌。
中晚期宫颈癌的综合治疗,临床上多采用联合放化疗+中医药治疗的模式。若患者身体机能能够耐受手术,应先尽早进行局部切除术,术后采用放化疗+中医药治疗,若病程晚,无法耐受手术切除,可行放化疗+中医药治疗,一方面可以综合中医西医的治疗优势,一方面中药能够减轻放化疗对人体的伤害,加快患者身体机能的恢复。若身体状况很弱,难以耐受西医治疗,或者西医治疗手段已经不起作用,可单纯采用中医药保守治疗,可一定程度上延长生存期,改善生存质量。
总的来说,不论如何治疗宫颈癌,分子靶向药物给宫颈癌患者带来新希望。靶向药物安体舒在选择性地杀灭癌细胞的同时对身体没有任何伤害,是目前治疗癌症最好的手段,是每一位肿瘤患者首选的药物。
Instruction of antitume
Drug name
Generic name: Chloroxoquinoline Capsules Brand name: AntitumeChinesespelling:LuYangKui JiaoNang
This product is composed of chloroxoquinoline mainly.
Its chemical name is 7-chlorin-4-oxygen-quinoline,and its content is higher than 98.5%.Empirical formula: C9H6CINOMolecular weight: 179.6
Description
Capsules, Its contents are white to white-off crystallinity powders.
Pharmacology and Toxicology
Pharmacology:Animal trials exhibit that chloroxoquinoline can inhibit mouse sarcoma S- 180 and EAC to some extent,and the Action Mechanismmaybe related to the inhibition of the DNA synthesis of cancer cells.
Pharmacokinetics
Pharmacokinetics in healthy volunteers is accordance with administration two-
compartment open model. Chloroxoquinoline is absorbed rapidly by gastrointestinal
tract, Peak blood drug level was attained within 1.25 hours and it was distributed
rapidly.And t1/2 α±0.958 hours and eliminate half life t1/2β±1.491 hours. The
pharmacokinetics of patient with nasopharyngeal cancer complies with I level absorptiontow-compartment open model. And peak blood drug level was attained within 1.6 hours,and t1/2α±0.07hours and t1/2β±1.29hours.
Indications
It is used to treat breast cancer and non-small cell lung cance,and so on.