Allergan公司宣布，FDA已批准面部皮下填充剂Juvederm的最新剂型——Juvederm XC，这是透明质酸（HA）皮下填充剂的最新进展。Juvederm XC含有局部麻醉剂利多卡因，可以降低使用过程中的不适感。目前，Juvederm是首个也是唯一获得FDA批准在使用后效果可持续1年的透明质酸类面部皮下填充剂。 Juvederm XC当中的利多卡因含量为0.3%，不含防腐剂，在使用时麻醉时间可以保持数秒，不需再使用其他麻醉剂。该产品效果保持时间与Juvederm相同，而且经过改良之后，爱美人士不但可以减轻用药不适之苦，还可以节省时间。 这种新型产品获准的依据是在一项多中心、双盲、随机临床实验当中获取的数据。在实验中，72名受试者分别使用Juvederm和Juvederm XC，针对去除鼻唇沟纹。研究人员在接下来的2周内对药物效果进行跟踪监测，结果发现用Juvederm XC受试组当中93%的人疼痛感更轻，而且其安全性和效果与Juvederm相当。  Juvederm XC receives FDA Approval  Juverderm XC becomes latest dermal filler to add a numbing agent Earlier this month, Juvederm XC, the latest dermal filler formulation from Allergan, received approval from the U.S. Food and Drug Administration for treating moderate to severe facial wrinkles and folds.   With this approval, Juvederm XC becomes the most recent in a line of dermal fillers—offered by various manufacturers—that contain the numbing agent lidocaine. Allergan reports that in a clinical study, 93 percent of patients reported less pain when treated with Juvederm XC than when treated with earlier non-lidocaine formulations of the filler.   Many physicians and others now believe that lidocaine-containing dermal fillers will soon be the treatment standard rather than the exception. Having lidocaine in the product eliminates the need for separate topical anesthetics—and greatly reduces any discomfort associated with the dermal filler procedure. The lidocaine acts almost instantly to numb the area being treated.   Juvederm XC contains hyaluronic acid, a naturally occurring substance with a smooth consistency. Although only a temporary solution to wrinkles and folds, Juvederm is one of the longest-lasting fillers on the market. A single treatment can last for up to 12 months. For best results, seek treatment from a physician who specializes in cosmetic skin procedures.