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当前位置:药品说明书与价格首页 >> 呼吸系统病 >> Novartis公司哮喘维持药Foradil获准在美上市

Novartis公司哮喘维持药Foradil获准在美上市

2010-04-04 17:25:17  作者:新特药房  来源:互联网  浏览次数:185  文字大小:【】【】【
简介: Novartis公司19日宣布:美国FDA已经批准该公司的速效,长效支气管扩张剂For adil(R)(延胡索酸formoterol吸入粉剂)在美上市用于哮喘病的维持治疗和气道阻塞性疾病的预防。 该药具有长期的哮喘症状控制 ...

Novartis公司19日宣布:美国FDA已经批准该公司的速效,长效支气管扩张剂For adil(R)(延胡索酸formoterol吸入粉剂)在美上市用于哮喘病的维持治疗和气道阻塞性疾病的预防。

该药具有长期的哮喘症状控制和快速支气管扩张双重疗效。1600名中重度哮喘患者参与的临床试验结果显示:Foradil (12mcg)可在长达12小时的时间内表现出显著的临床支气管扩张效果。该药的起效时间为1—3分钟,与短效beta-2激动剂沙丁胺醇相似。

Foradil的使用方法为通过一种名为Aerolizer的干粉吸入机每日吸入两次,这种吸入机与其它定量吸入机不同,它的吸入阻力小,并且发出声音提示药物正在被吸入。患者可通过味觉或打开机器检查来判断是否吸入了全部药物。

该药目前已在85个国家上市。全球阻塞性肺疾病组织和哮喘病组织确认该药为慢性阻塞性肺疾病(COPD)和哮喘的高效药物,并将其列入治疗建议;

 FORADIL INHALER (FORMOTEROL FUMARATE) (OXIS) 12mcg 60 tbs

Product Description

Foradil Inhaler is a drug with generic name of Formoterol Fumarate or Oxis. Foradil Inhaler is a long-acting selective beta 2-adrenergic receptor agonist that functions in the lungs as a bronchodilator.
Foradil Inhaler relaxes the muscles in the walls of the airways, allowing such to expand. Foradil helps to manage asthma in people who need customary treatment with short-acting inhalers, including those with nighttime asthma. Foradil Inhaler also helps to relive tightening of the airways of people with Chronic Obstructive Pulmonary Disease, including chronic bronchitis and emphysema.


Foradil Inhaler Indications
Foradil is indicated to prevent asthma attacks. Foradil Inhaler should not be used for the relief of acute asthma symptoms. There are other prescribed medications for acute asthma attacks such as Proventil or Ventolin.
Foradil Inhaler is also indicated for the acute prevention of exercise-induced bronchospasm in adults and children 5 years of age and older.
Foradil Inhaler is indicated for the long-term, twice a day administration in the maintenance treatment of bronchoconstriction in patients with Chronic Obstructive Pulmonary Disease.


Foradil Inhaler Warnings
Do not use Foradil Inhaler to treat acute asthma. Foradil Inhaler has not been studied to relive acute asthma. Foradil Inhaler is not a replacement for corticosteroids. Do not stop taking corticosteroids at the time that Foradil Inhaler is initiated.
Caution should be initiated for patients taking Foradil Inhaler with the following conditions:
Hypertension
Cardiac arrhythmias
Cardiovascular disorders, especially coronary insufficiency
Convulsive disorders or Thyrotoxicosis
Diabetes mellitus and ketoacidosis

Foradil Inhaler Dosage
For long-term control of asthma in adults and children 5 years of age and older, the dosage of Foradil is one capsule every 12 hours.
For the prevention of exercise-induced asthma in adults and children 12years of age and older, the dosage of Foradil is one capsule at least 15 minutes before exercise. If a second dose of Foradil is a necessary need for the same day, it must be taken at least 12 hours after the first dose.
For the prevention of chronic obstructive pulmonary disease, the usual dosage of Foradil is one capsule every 12 hours. It is very important for you to check your doctor if the normal dosage fails to provide the typical relief.


Foradil Inhaler Overdose
Symptoms of Foradil Inhaler overdose may include the following:
Chest pain
Dizziness
Dry mouth
Fast or irregular heartbeat
Fatigue
General feeling of illness
Headache
Heart palpitations
Inability to sleep
Muscle cramps
Nausea
Nervousness
Seizures
Tremor
Other overdose of Foradil Inhaler not mentioned here may also occur. Consult your doctor immediately if you suspect an overdose of Foradil Inhaler.


Foradil Inhaler Missed Dose
Immediately take the missed dose of Foradil Inhaler as soon as you remember but if it is almost time for the next dose, skip the missed one and take the subsequent dose according to schedule. It is important to remember not to take a double dose of Foradil Inhaler medication.


Foradil Inhaler Side Effects
Side effects of Foradil Inhaler may include the following:
Allergic reactions
Abdominal pain
Back pain
Chest infection
Bronchitis
Difficulty speaking
Difficulty breathing
Anxiety
Fatigue
High blood sugar
High or low blood pressure
Sinusitis
Sore throat
Stomach upset
Tonsillitis
Fever
Headache
Indigestion
Irregular heartbeat
Muscle cramps
Upper respiratory and viral infections
Worsening of asthma
Other side effects of Foradil Inhaler not mentioned here may also occur. Talk to your doctor or physician if you experience the said side effects or if you feel anything unusual or bothersome effects.


Foradil Inhaler Drug Reactions
Several drugs may interfere with the original function of Foradil Inhaler. Talk to your doctor first before using any of the following drugs:
Tricyclic Antidepressants such as Elavil and Tofranil
Monoamine Oxidase Inhibitors such as Nardil and Parnate
Beta Blockers such as Inderal and Tenormin
Steroids such as Prednisone and Hydrocortisone
Thephylline
Water Pills or Diuretics such as HydroDiuril or Lasix

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