制造商：
眼力健
药理分类：
抗生素（喹诺酮类）
活性成分（补）：
加替沙星0.5％;蛇夫座溶液，含有苯扎氯。
指示（补）：
易患细菌性结膜炎。
药理作用：
Zymaxid是对氟喹诺酮类抗生素，加替沙星，这是针对革兰氏阳性和革兰氏阴性菌广泛有效滴眼液的制定。它被用于治疗由金黄色葡萄球菌，表皮葡萄球菌，缓症链球菌群，口腔链球菌，肺炎链球菌，流感嗜血杆菌或感受性细菌引起细菌性结膜炎。
加替沙星也可在0.3％的力量用于治疗敏感细菌感染眼结膜溶液（Zymar，也从Allergan公司）。
临床试验：
加替沙星眼用溶液0.5％疗效评价两项随机，双盲，双手臂比较，涉及1437名年龄1-89岁的临床试验。无论使用哪种加替沙星滴眼液0.5％或车辆剂量是持续5天。研究药物被证明是天与结膜炎和结膜培养阳性6例患者临床优于车辆。临床成功证明结膜充血和排放的决议。在特定药物的研究组，58％的患者有临床的成功相比，45％的人给出的车辆。百分之九十的患者使用药物的研究相比，有百分之70％的安慰剂消灭病原微生物。
法律分类：
接收
成人和儿童：
<1年：不推荐。 ≥一年：一下降，受影响的眼睛天（南）（最多8次），每2小时，然后在受影响的眼药水1（s），每天2-4次在清醒时第2-7天。
警告/注意事项：
摘掉隐形眼镜。如果停止或过敏发生重叠。妊娠（Cat.C）。哺乳的母亲。
不良反应（补）：
结膜炎恶化，刺激，味觉障碍，眼痛/放电。
如何提供：
溶液，2.5毫升
最后更新：
2010年7月1日
Manufacturer:
Allergan
Pharmacological Class:
Antibiotic (quinolone)
Active Ingredient(s):
Gatifloxacin 0.5%; oph soln; contains benzalkonium chloride.
Indication(s):
Susceptible bacterial conjunctivitis.
Pharmacology:
Zymaxid is an ophthalmic solution formulation of the fluoroquinolone antibiotic, gatifloxacin, which is effective against a wide range of gram positive and gram negative bacteria. It is indicated for treating bacterial conjunctivitis caused by susceptible strains of Staphylococcus aureus, Staphylococcus epidermidis, Streptococcus mitis group, Streptococcus oralis, Streptococcus pneumoniae, or Haemophilus influenzae.
Gatifloxacin is also available in a 0.3% strength ophthalmic solution for the treatment of susceptible bacterial conjunctival infections (Zymar, also from Allergan).
Clinical Trials:
The efficacy of gatifloxacin 0.5% ophthalmic solution was evaluated in two randomized, double-masked, dual-arm comparison clinical trials involving 1,437 patients aged 1–89 years of age. Dosing with either gatifloxacin ophthalmic solution 0.5% or vehicle was continued for five days. The study drug was shown to be clinically superior to vehicle on day 6 in patients with conjunctivitis and positive conjunctival cultures. Clinical success was evidenced by resolution of conjunctival hyperemia and discharge. In the group given the study drug, 58% of patients had clinical success compared to 45% for those given the vehicle. Ninety percent of the patients using the study drug had microbiological eradication of the causative pathogens compared to 70% for placebo.
Legal Classification:
Rx
Adults & Children:
<1year: not recommended. ≥1year: one drop every 2 hrs in affected eye(s) (max 8 doses) on day 1, then 1 drop in affected eye(s) 2–4 times daily while awake on days 2–7.
Warnings/Precautions:
Remove contact lenses. Discontinue if superinfection or hypersensitivity occurs. Pregnancy (Cat.C). Nursing mothers.
Adverse Reaction(s):
Worsening conjunctivitis, irritation, dysgeusia, eye pain/discharge.
How Supplied:
Soln—2.5mL