通用名称为INVEGA
Paliperidone为1.5mg，3毫克，6mg，9mg; EXT - REL标签。
法律分类：
接收
药理班级INVEGA
Benzisoxazole。
制造商INVEGA
杨森制药产品，LP
适应症INVEGA
急性和维持治疗精神分裂症的成年人。急性治疗分裂情感障碍的成年人，作为单一疗法或作为情绪稳定剂和/或抗抑郁药的辅助手段。治疗精神分裂症的12岁的青少年，17yrs。
成人剂量为INVEGA
燕子的整体。 ≥18yrs：6mg每日上午一次，可能会增加在3mg/day增量在>4天间隔（分裂情感障碍）或> 5天（精神分裂症）如果需要的话。正常范围：3-12mg/day。最大12mg/day。保养：使用最低有效剂量。肾损伤：肌酐清除率≥50 - <80mL/min：最大6mg/day;肌酐清除率10 - <50mL/min：最大3mg/day。
儿童剂量为INVEGA
分裂情感障碍：<18yrs：不推荐。精神分裂症：<12岁：不推荐。 12 - 17yrs：（<51千克）：最初3毫克每日上午一次，通常范围：3-6mg/day，最大6mg/day（≥51公斤）：最初3毫克每日上午一次，通常范围：3-12mg/day ;最大12mg/day。这两种：可能在3mg/day增量增加> 5天的时间间隔，如果需要。
警告/注意事项为INVEGA
长者（不适用于痴呆相关的精神病）：死亡的风险增加。避免在先天性长QT综合征，心律失常。如果停止抗精神病药恶性综合征（NMS）发生;考虑不再如果发生迟发性运动障碍。糖尿病的危险因素（获得基线空腹血糖）。心或脑血管疾病，风险可能会增加，由于代谢的变化（例如，高血糖，血脂异常，体重增加）;显示器。预现有的低白细胞或历史的白细胞减少/中性粒细胞减少;在第一几个月的治疗监测CBCS;停止，如果白细胞下降。体位性低血压。帕金森氏病。路易体痴呆症。历史的发作。患者在吸入性肺炎的危险。肾功能不全。严重肝损害。暴露在极端温度。可有止呕作用。自杀的病人。标签：预先存在的严重的胃肠道狭窄：不推荐。定期重新评估。妊娠（Cat.C）。哺乳母亲：不推荐。
相互作用的INVEGA
避免酒精，药物延长QT间隔（如类，Ⅲ类抗心律失常药和1A，氯丙嗪，硫利达嗪，加替沙星，莫西沙星）。注意与其他中枢神经系统的药物，药物可引起体位性低血压。可能是拮抗卡马西平，调整剂量。五月拮抗左旋多巴，多巴胺受体激动剂等。可能是potentiated由双丙戊酸钠钠;考虑减少剂量。
为INVEGA不良反应
锥体外系症状，静坐不能，嗜睡，震颤，肌张力障碍，齿轮刚性，焦虑，体重增加，心动过速，消化不良，便秘，鼻咽炎，可能会引起NMS，迟发性运动障碍，QT间期延长，高血糖，血脂异常，体位性低血压，晕厥，高泌乳素血症，异常勃起。
如何INVEGA提供？
标签- 30
INVEGA (PALIPERIDONE)
Invega Information
Invega is a common antipsychotic remedy. Some of you may be familiar with this product but may know it under the generic name of Paliperidone. The use of such a medication is able to achieve its needed results by changing the effects that certain brain chemicals are supposed to have.
Invega Indications
As Invega is an antipsychotic drug, it is mainly employed in the therapy course of patients who have been diagnosed with schizophrenia, or any medical conditions related to schizophrenia. However, in case a medical professional considers is necessary, a treatment course with this drug can also be applied in the case of patients who suffer from other medical conditions that have not been listed here.
Invega Warnings
Although this product is effective in the case of patients with schizophrenia, individuals who are suffering from dementia or any conditions related to it should not be allowed to use Invega. In such clinical cases, a therapy course with this antipsychotic product, can lead to the developing of several severe complications: heart failure, pneumonia, sudden death, and so on, especially in the case of elderly individuals (patients over 60 years of age). Patients who are being treated with Invega or who are to start a therapy course with this product should be warned that during their treatment they may become more sensitive to temperature changes (especially to temperature extremes, such as very cold or very hot weather / conditions). Thus, dehydration can easily occur in the case of patients who are being treated with this type of medication.
The easiest way to prevent experiencing this unpleasant (and potentially severe) medical condition is to drink large quantities of liquids during your therapy course with Invega. As a therapy course with this medication can trigger a set of adverse manifestations that can impair one’s reactions and / or thinking, certain activities should be avoided during one’s treatment with this antipsychotic. As the use of alcohol is known to enhance the severity of such effects, patients being treated with Invega must avoid the consumption of such beverages. Studies have shown that this product is a category C FDA product. Pregnant / nursing mothers must avoid employing such a medication. This matter should be discussed with the female’s gynecologist. A therapy course with Invega can sometimes trigger hyperglycemia. This is especially bothersome in the case of diabetics that require extra medical attention during their treatment.
Invega Intake Guidelines
It is important to use all of your doses of this drug exactly how they were prescribed in your particular clinical case. Your PD is to provide you with several directions concerning your future or current therapy course with Invega. You may also find such pieces of medical information in the product’s professional label. As the special formula of a capsule of Invega prevents it from triggering the unpleasant clinical manifestations of stomach upset, a patient can employ a dose of this medication either on a full or on an empty stomach. However, it is very important not to chew the tablets of this medication, as they have been designed in order to gradually release their special ingredient during a well determined period of time. Another way in which you can enhance the beneficial results of your therapy course is by employing all of your prescribed doses of this medication at their due time.
Invega Dosage
You will have to undergo certain medical tests before your medical prescriber can determine without any further doubts the needed amount of Invega that you are to be administered during your therapy. In certain cases, some patients are prescribed low doses of this product in their initial stages of their therapy, but their dose gradually increases in time. However, before a patient can stop using Invega, he or she will have to start employing lower and lower doses of this medication, in order to avoid experiencing withdrawal symptoms.
Invega Overdose
Any patient who is suspected to suffer from such a medical condition should immediately seek the needed emergency clinical attention. There are several symptoms that are commonly associated with such a condition (Invega over-dosage); they include: light-headedness, fast heart rate, drowsiness, fainting, abnormal muscle movements that affect the jaw, tongue, eyes or neck, and so on.
Invega Missed Dose
Missed doses of this medical product can impair the effectiveness of one’s therapy course with this medication. In case you are unable to stick to your current treatment schedule you should refer to your medical professional. Together you will make the needed alterations to your Invega dosing routine. Your PD is the only one who can advise you concerning the appropriate way of action in case you accidentally miss one or more of your scheduled doses of Invega. Doubling up doses of this medication is not recommended.
Invega Side Effects
As with most other medical products, the use of Invega can lead to the developing of certain unwanted reactions. Confusion, fever, sweating, muscle stiffness, uneven or fast heartbeat, tremor, decreased sex drive, upset stomach, headache, dizziness, blurred vision, impotence, and so on, are symptoms that can commonly be accused by a patient who is being treated with this antipsychotic.
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INVEGA
Generic Name for INVEGA
Paliperidone 1.5mg, 3mg, 6mg, 9mg; ext-rel tabs.
Legal Classification:
Rx
Pharmacological Class for INVEGA
Benzisoxazole.
Manufacturer of INVEGA
Janssen Pharmaceutica Products, LP
Indications for INVEGA
Acute and maintenance treatment of schizophrenia in adults. Acute treatment of schizoaffective disorder in adults, as monotherapy or as an adjunct to mood stabilizer and/or antidepressants. Treatment of schizophrenia in adolescents 12–17yrs of age.
Adult dose for INVEGA
Swallow whole. ≥18yrs: 6mg once daily in AM; may increase in increments of 3mg/day at intervals of >4 days (for schizoaffective disorder) or >5 days (for schizophrenia) if needed. Usual range: 3–12mg/day. Max 12mg/day. Maintenance: use lowest effective dose. Renal impairment: CrCl ≥50–<80mL/min: max 6mg/day; CrCl 10–<50mL/min: max 3mg/day.
Children's dosing for INVEGA
Schizoaffective disorder: <18yrs: not recommended. Schizophrenia: <12yrs: not recommended. 12–17yrs: (<51kg): initially 3mg once daily in AM; usual range: 3–6mg/day; max 6mg/day; (≥51kg): initially 3mg once daily in AM; usual range: 3–12mg/day; max 12mg/day. Both: may increase in increments of 3mg/day at intervals of >5 days if needed.
Warnings/Precautions for INVEGA
Elderly (not for dementia-related psychosis): increased risk of death. Avoid in congenital long QT syndrome, cardiac arrhythmias. Discontinue if neuroleptic malignant syndrome (NMS) occurs; consider discontinuing if tardive dyskinesia occurs. Diabetes risk factors (obtain baseline fasting blood sugar). Cardio- or cerebrovascular disease; risks may be increased due to metabolic changes (eg, hyperglycemia, dyslipidemia, weight gain); monitor. Pre-existing low WBCs or history of leukopenia/neutropenia; monitor CBCs during 1st few months of treatment; discontinue if WBCs decline. Orthostatic hypotension. Parkinson's disease. Dementia with Lewy bodies. History of seizures. Patients at risk for aspiration pneumonia. Renal insufficiency. Severe hepatic impairment. Exposure to extreme temperatures. May have antiemetic effect. Suicidal patients. Tabs: Pre-existing severe GI narrowing: not recommended. Reevaluate periodically. Pregnancy (Cat.C). Nursing mothers: not recommended.
Interactions for INVEGA
Avoid alcohol, drugs that prolong QT interval (eg, Class 1A and Class III antiarrhythmics, chlorpromazine, thioridazine, gatifloxacin, moxifloxacin). Caution with other CNS drugs, drugs that may cause orthostatic hypotension. May be antagonized by carbamazepine; adjust dose. May antagonize levodopa, other dopamine agonists. May be potentiated by divalproex sodium; consider dose reduction.
Adverse Reactions for INVEGA
Extrapyramidal symptoms, akathisia, somnolence, tremor, dystonia, cogwheel rigidity, anxiety, weight gain, tachycardia, dyspepsia, constipation, nasopharyngitis; may cause NMS, tardive dyskinesia, QT prolongation, hyperglycemia, dyslipidemia, orthostatic hypotension, syncope, hyperprolactinemia, priapism.
How is INVEGA supplied?
Tabs—30