【拼音名】: YANSUAN TEBINAIFEN PENWUJI
【性状】: 盐酸特比萘芬喷雾剂为无色澄明液体。
【适用症】盐酸特比萘芬喷雾剂用于治疗敏感真菌所致的手癣、足癣、体癣、股癣及花纹斑癣等。
【注意事项】
1. 仅供外用,避免误入眼内。应放在儿童不能触及处。
2. 使用过程中如出现不良反应症状,应停止用药。
3. 疗程一般不超过4周。
【用法与用量】外用,喷于患处,一日2~3次,疗程1~2周或遵医嘱。
【禁忌症】对特比萘芬或盐酸特比萘芬喷雾剂中任何成分过敏者禁用。
【孕妇、哺乳期妇女用药注意事项】动物研究显示盐酸特比萘芬喷雾剂对胎儿无任何不良影响,但在孕妇中尚未经过对照试验验证,所以孕妇不推荐使用,除非利远大于弊。盐酸特比萘芬喷雾剂可从乳汁中排出。虽然量很少,但使用盐酸特比萘芬喷雾剂的妇女应停止给婴儿哺乳。
【不良反应】皮肤局部轻度烧灼感、瘙痒感等刺激症状或局部皮肤干燥。一般不影响治疗。
【药物相互作用】尚不明确。
【药理】盐酸特比萘芬为丙烯胺类广谱抗真菌药物。能特异性地干扰真菌固醇的早期生物合成,选择性地抑制真菌的角鲨烯环氧化酶的活性,使真菌细胞膜形成过程中角鲨烯环氧化反应受阻,角鲨烯在细胞中蓄积,从而达到杀灭或抑制真菌的作用。
【药物代谢动力学】局部涂抹后,被吸收的药量不超过用药量的5%,故全身血药浓度极低,盐酸特比萘芬喷雾剂生物转化后的代谢物无抗真菌作用,主要经尿液和粪便排出体外,消除半衰期为17小时,无体内蓄积现象。
【包装规格】: 1支/盒,塑料瓶包装。
【贮藏】: 密封,在阴凉处保存。
【有效期】: 暂定2年。
Drug Name: terbinafine spray
English: Terbinafine Hydrochloride Spray
Pinyin:
main components: major components of the goods for terbinafine
traits: $ colorless liquid clarity .
pharmacological effects: $ broad-spectrum antifungal. Fungi can specifically interfere with the early steroid biosynthesis, selectively inhibit fungal Squalene cyclooxygenase activity, the fungal cell membrane formation of Squalene epoxidation of disruption to meet kill or inhibit fungal role.
Pharmacokinetics: local smear, the drug is absorbed dosage of less than 5% is very low systemic blood concentration, the goods after the metabolic biotransformation of special anti-fungal effect mainly by the urine and feces they excreted, the elimination half-life of 17 hours and no accumulation in the body.
indications: by skin fungi, yeast and other fungi from the body ringworm, tinea corporis and cruris, hand, foot and ringworm, tinea versicolor.
usage and consumption: topical, spraying the skin, on the 1st 2 to 3 times, a treatment to two weeks or compliance.
adverse reaction: dual use in a location redness, itching or hibernate sting, but rarely result withdrawal. Note: These symptoms must be with those very rare but must be differentiated from stopping the allergic reaction.
of taboos: right terbinafine or any of the goods are allergic ingredients prohibited.
Note: only to avoid accidentally eyes. Children should not touch on the Department.
pregnancy and lactation:
animal studies show that the goods to the fetus without any adverse effects, but in pregnant women has not been verified controlled trials, so pregnant women not recommended, unless benefits than disadvantages.
terbinafine may be discharged from the milk, although the volume low, but women should be using this to stop breast-feeding babies.
specifications: 15ml: 0.15 g.
Storage: sealed, the preservation of the shade.
Validity: tentative 2002.
prescription drugs:
Warning:The information is only as a reference for new drug researcher and the patients or doctors can't use it as prescription basis!
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