Therapeutic category: Beta1-Blocker
Composition: Each extended release film-coated tablet contains S-metoprolol succinate equivalent to S-metoprolol tartrate …12.5 mg / 25 mg / 50 mg
Indication: Hypertension, Angina, Heart-failure, Post-MI
Dose (adults): 12.5-100 mg once daily depending upon indication
Advantages:
Provides the beta-1 blocker component only
At half the racemate dose
Avoiding the beta-2 blocking component
Can be administered at high doses
Without causing beta-2 receptor mediated side effects
Safer in poor metabolizers of CYP2D6
Avoids many drug-drug interactions
中文名称: 美托洛尔
中文同义词:
英文名称: (S)-(-)-METOPROLOL
英文同义词: (S)-(-)-METOPROLOL;2-Propanol, 1-[4-(2-methoxyethyl)phenoxy]-3-[(1-methylethyl)amino]-, (2S)- (9CI);2-Propanol, 1-[4-(2-methoxyethyl)phenoxy]-3-[(1-methylethyl)amino]-, (S)-;(2S)-1-[4-(2-Methoxyethyl)phenoxy]-3-[(1-methylethyl)amino]-2-propanol
CAS号: 81024-42-2
分子式: C15H25NO3
分子量: 267.36
EINECS号: