英文药名: VALSARTAN TABLETS(Valsartan)

中文药名: 缬沙坦片

生产厂家: 第一三共制药
药品简介
缬沙坦是第二个血管紧张素Ⅱ（AngⅡ）受体拮抗剂(ARB)。临床用于治疗轻、中度原发性高血压，尤其适用于对ACE抑制剂不耐受的患者。缬沙坦具有新一代血管紧张素IIAT1受体拮抗剂的优点，与血管紧张素转换酶抑制剂(ACEI) 药物相比，其竞争性地直接作用于AT1受体，使血管平滑肌松弛、血管扩张，改善心室及血管重塑；同时可提高肾血流灌注量，增加水、钠排泄，减少血容量，而使血压下降；降压作用可靠、安全、副作用小；口服后可直接起效，且维持降压时间较长。
适应症
轻、中度原发性高血压
用法用量
成人通常给予每日一次口服40〜80毫克。另外服用根据年龄，则增加或减少适当根据症状，它可以提高到1天160mg。
儿童（超过6岁的）如果体重低于35千克，在20毫克，如果超过体重35千克，口服给药，每天一次40毫克。此外，将根据年龄，体重和症状调整。然而，每日最大剂量，在体重低于35公斤和40毫克的情况下
包装规格
20毫克“DSEP”（PTP）100片140片（14片×10）
40毫克“DSEP”（PTP）100片140片（14片×10）700片（14片×50）（瓶）500粒
80毫克“DSEP”（PTP）100片140片（14片×10）700片（14片×50）（瓶）500粒
160mg“DSEP”（PTP）100片140片（14片×10）
生产厂商
第一三共有限公司Esufa
VALSARTAN TABLETS 20mg "DSEP"（バルサルタン錠20mg「DSEP」）
Brand name : VALSARTAN TABLETS 20mg "DSEP"
　Active ingredient: Valsartan
　Dosage form: pale yellow tablet, diameter 7.1 mm, thick 2.6 mm
　Print on wrapping: (front) バルサルタン20mg「DSEP」, 第一三共エスファ, バルサルタン, 20, 20mg, (back) VALSARTAN 20mg「DSEP」, 血圧降下薬, バルサルタン20mg「DSEP」, 20
Effects of this medicine
This medicine binds to angiotensin II receptor produced in the body, and inhibits the hypertensive activity of angiotensin II by blocking its vasoconstriction action. And then it lowers blood pressure in hypertensive patient.
It is usually used to treat hypertension.
Before using this medicine, be sure to tell your doctor and pharmacist
•If you have previously experienced any allergic reactions (itch, rash, etc.) to any medicines.
If you have diabetes mellitus, renal disorder, hyperpotassemia.
If you are receiving hemodialysis.
If you are dietary salt restriction.
If you are scheduled in surgery.
•If you are pregnant, possibly pregnant or breastfeeding.
•If you are taking any other medicinal products. (Some medicines may interact to enhance or diminish medicinal effects. Beware of over-the-counter medicines and dietary supplements as well as other prescription medicines.)
Dosing schedule (How to take this medicine)
•Your dosing schedule prescribed by your doctor is <<to be written by a healthcare professional>>
•For adults: In general, take 40 to 80 mg of the active ingredient at a time, once a day. The dose may be adjusted according to the age or symptoms. However, daily dose may be increased to 160 mg.
For children aged 6 years and older: In general, for children weighing less than 35 kg, take 20 mg of the active ingredient at a time, once a day. For children weighing 35 kg and more, take 40 mg at a time, once a day. The dose may be adjusted according to the age, body weight or symptoms. However, for children weighing less than 35 kg, the maximum daily dose is restricted to 40 mg.
This medicine contains 20 mg of the ingredient in a tablet. Strictly follow the instructions in any case.
•If you miss a dose, take a dose as soon as you remember. However, if there are less than about 8 hours before the next dose, skip the missed dose and follow your regular dosing schedule. You should never take two doses at one time.
•If you accidentally take more than your prescribed dose, consult with your doctor or pharmacist.
•Do not stop taking this medicine unless your doctor instructs you to do so.
Precautions while taking this medicine
•Dizziness or lightheadedness may occur due to decreased blood pressure. Take care in working at heights, driving a car or operating dangerous machinery.
Possible adverse reactions to this medicine
The most commonly reported adverse reactions include dizziness, headache, palpitation, abdominal pain, cough, malaise, rash, hypotension, itch, hives, erythema and photosensitivity. If any of these symptoms occur, consult with your doctor or pharmacist.
The symptoms described below are rarely seen as initial symptoms of the adverse reactions indicated in brackets. If any of these symptoms occur, stop taking this medicine and see your doctor immediately.
•swelling of lips/tongue, respiratory distress [angioedema]
•loss of appetite, general malaise, yellowness in the skin and/or the white of the eye [hepatitis]
•decrease of urine output, swelling of limbs, loss of appetite [renal failure]
•muscle weakness, numbness of limbs/lips, paralysis in limbs [hyperpotassemia]
•loss of consciousness, vomiting, cold feeling [shock, syncope, loss of consciousness]
The above symptoms do not describe all the adverse reactions to this medicine. Consult with your doctor or pharmacist if you notice any symptoms of concern other than those listed above.
Storage conditions and other information
•Keep out of the reach of children. Store away from direct sunlight, heat and moisture.
•Discard the remainder. Do not store them.
DAIICHI SANKYO ESPHA CO., LTD.Internal
Published: 6/2014
The information on this sheet is based on approvals granted by the Japanese regulatory authority. Approval details may vary by country. Medicines have adverse reactions (risks) as well as efficacies (benefits). It is important to minimize adverse reactions and maximize efficacy. To obtain a better therapeutic response, patients should understand their medication and cooperate with the treatment
http://www.info.pmda.go.jp/go/pack/3399008F1319_1_01/3399008F1319_1_01?view=body
http://www.info.pmda.go.jp/go/pack/2149041F1055_1_03/