通用名称,剂型:
糠酸莫米松110mcg/inh,220mcg/inh密码口腔吸入,计量吸入器。
适应症ASMANEX TWISTHALER:
维持治疗哮喘的预防性治疗。
公司名称:
默克制药公司
Generic Name and Formulations:
Mometasone furoate 110mcg/inh, 220mcg/inh; pwd for oral inhalation, metered-dose inhaler.
Company:
Merck & Co., Inc.
Indications for ASMANEX TWISTHALER:
Maintenance treatment of asthma as prophylactic therapy.
Adult Dose for ASMANEX TWISTHALER:
Previously on bronchodilators alone or inhaled corticosteroids: initially 220mcg once in the PM; max 440mcg daily (either as 220mcg twice daily or 440mcg once daily). Previously on oral corticosteroids (wean gradually): initially 440mcg twice daily; max 880mcg daily. Rinse mouth after use.
Children's Dose for ASMANEX TWISTHALER:
<4yrs: not recommended. 4–11yrs: 110mcg once in the PM; max 110mcg daily. Rinse mouth after use.
Pharmacological Class:
Steroid.
Contraindications:
Not for treatment of acute attacks. Milk protein allergy.
Warnings/Precautions:
Maintain regular regimen. Infections. If exposed to chickenpox or measles, consider anti-infective prophylactic therapy. Monitor intraocular pressure; bone mineral density if other osteoporosis risk factors exist; and for growth suppression in children; hypercorticism and HPA axis suppression (if occurs, discontinue gradually). If adrenal insufficiency exists following systemic corticosteroids, replacement with inhaled steroids may exacerbate symptoms of adrenal insufficiency (eg, lassitude). Prescribe a short-acting, inhaled β2-agonist for acute symptoms; monitor for increased need. Pregnancy (Cat. C). Nursing mothers.
Interactions:
Caution with potent CYP3A4 inhibitors (eg, ketoconazole).
Adverse Reactions:
Headache, respiratory or other infection, oral candidiasis, dysmenorrhea, musculoskeletal pain, GI upset, allergic rhinitis, sinus congestion, sinusitis, depression, fatigue, pain, bronchospasm (discontinue if occurs). Children: fever, bruise.
How Supplied:
Twisthaler 110mcg (30 inh)—1; 220mcg (30 inh, 60 inh, 120 inh)—1
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