英文药名：Flutiform Aerosol（Fluticasone Propionate/Formoterol Fumarate Hydrate）

中文药名：复方丙酸氟替卡松/富马酸福莫特罗吸入剂

生产厂家：杏林药业
类别名称
哮喘的治疗配方
欧文商標名
Flutiform Aerosol
丙酸氟替卡松
一般名：
フルチカゾンプロピオン酸エステル(Fluticasone Propionate)
化学名：
S-Fluoromethyl 6α,9α-difluoro-11β-hydroxy-16α-methyl-3-oxo-17α-propionyloxyandrost-1,4-diene-17β-carbothioate
分子式：C25H31F3O5S
分子量：500.57
融点　：272～273℃
性状　
白色或几乎白色粉末。 N和易溶于N-二甲基甲酰胺，略微溶于丙酮或二氯甲烷中，微溶于乙醇（96％），和几乎不溶于水。
化学構造式：

富马酸福莫特罗水合物
一般名：
ホルモテロールフマル酸塩水和物(Formoterol Fumarate Hydrate)
化学名：
N-(2-Hydroxy-5-{(1RS)-1-hydroxy-2-[(1RS)-2-(4-methoxyphenyl)-1-methylethylamino]ethyl}-phenyl)formamide hemifumarate monohydrate
分子式：(C19H24N2O4)2・C4H4O4・2H2O
分子量：840.91
融点　：約138℃（分解）
性状　
它是白色结晶粉末，以黄色。乙酸（100）可溶于，略溶于甲醇，极微溶于水或乙醇（95），并在乙醚中几乎不溶。
化学構造式：

操作注意事项
1. 对患者指导如何使用
2. 病人喷雾吸入气溶胶的调谐被认为难以使用的间隔（吸入辅助设备）
3. 它是用来摇匀。
4. 储存注意事项
适应症
支气管哮喘（凡吸入类固醇和长效相结合β2吸了一口兴奋剂是必需的）
用法用量
成人，吸入，一天两次是一种低剂量制剂50气雾剂一次2吸入。然后吸入一次2-4吸入，每日两次。请严格按照吸入方法的说明。（请仔细阅读使用说明书）
制造厂商
杏林药业有限公司

http://www.info.pmda.go.jp/go/pack/2290802G3026_1_02/
Brand name : Flutiform 50 Aerosol 56 puffs
　Active ingredient: Fluticasone propionate, Formoterol fumarate hydrate
　Dosage form: Inhaled aerosol, sky blue line and sky blue letters on the label
　Print on wrapping: フルティフォーム50エアゾール56吸入用
---------------------------------
Brand name : Flutiform 125 Aerosol 56 puffs
　Active ingredient: Fluticasone propionate, Formoterol fumarate hydrate
　Dosage form: Inhaled aerosol, pink line and pink letters on the label
　Print on wrapping: フルティフォーム125エアゾール56吸入用
---------------------------------
Effects of this medicine
This medicine is a combination inhaler that contains a steroid used to suppress inflammation in the airways and a long-acting bronchodilator used to dilate bronchi over a long time.
It is usually used in the treatment of bronchial asthma. It is not effective for sedating an asthma attack which has already developed.
Before using this medicine, be sure to tell your doctor and pharmacist
•If you have previously experienced any allergic reactions (itch, rash, etc.) to any medicines.
If you are a patient with infections, deep mycosis, tuberculosis, hyperthyroidism, hypertension, cardiac disease, diabetes, hypokalemia or hepatic disorder.
•If you are pregnant or breastfeeding.
•If you are taking any other medicinal products. (Some medicines may interact to enhance or diminish medicinal effects. Beware of over-the-counter medicines and dietary supplements as well as other prescription medicines.)
Dosing schedule (How to take this medicine)
•Your dosing schedule prescribed by your doctor is <<to be written by a healthcare professional>>
•In general, for adults, take two inhalations of the medicine (Flutiform 50 Aerosol) at a time, twice daily. Depending on the symptoms, the medicine can be replaced with "high-dose" Flutiform 125 Aerosol. Strictly follow the specified instructions.
•Read carefully the instruction leaflet "To Patients Using Flutiform".
•Shake the inhaler immediately before using.
•An inhaler can be sprayed for 56 puffs. If the inhaler is new or it has not been used for more than 3 days then it must be sprayed 4 times in the air before using. When you press the aluminum canister, the dose counter on an adapter works automatically and shows green, yellow and finally red in response to use. Confirm the counter every day. When this is getting near to red, you should contact your doctor for a replacement inhaler. When this is getting to zero, you should use a new inhaler.
•Gargle the throat after inhaling. If you are hard to gargle, rinse out your mouth.
•If you miss a dose, inhale a dose as soon as possible when you remember that you missed a dose. If it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. You should never inhale two doses at one time.
•If you accidentally inhale more than your prescribed dose, consult with your doctor or pharmacist.
•Do not stop inhaling this medicine unless your doctor instructs you to do so.
Precautions while taking this medicine
•When you experience an asthma attack, take prescribed medicine for stopping an attack, or visit your doctor or a healthcare facility as soon as possible.
Possible adverse reactions to this medicine
The most commonly reported adverse reactions include hoarseness (hoarse voice), palpitations, asthma, stomatitis, pharyngitis, rash and urticaria. If any of these symptoms occur, consult with your doctor or pharmacist.
The symptoms described below are rarely seen as initial symptoms of the adverse reactions indicated in brackets. If any of these symptoms occur, stop taking this medicine and see your doctor immediately.
•dyspnea, generalized flushing, urticaria [shock, anaphylaxis]
•lassitude, loss of muscular strength, paralysis of the limbs [serious decreases in serum potassium levels]
•fever, cough, phlegm [pneumonia]
The above symptoms do not describe all the adverse reactions to this medicine. Consult with your doctor or pharmacist if you notice any symptoms of concern other than those listed above.
Storage conditions and other information
•Do not detach the inner aluminum canister from the adapter.
•Wipe well outside and inside of mouthpiece with dry cloth or tissue paper at least once or more a week to avoid clogging of a spray outlet, and keep the device clean. Keep the aluminum canister dry.
•Keep out the reach of children. Store it at a temperature of lower than 30℃, away from direct sunlight, heat and moisture.
•Do not store the remainder and discard it. Follow the instruction on how to dispose of aluminum canister specified by local authorities after using. Do not throw the aluminum canister into the fire.
Kyorin Pharmacetical Co.,LtdExternal
Published: 11/2013
The information on this sheet is based on approvals granted by the Japanese regulatory authority. Approval details may vary by country. Medicines have adverse reactions (risks) as well as efficacies (benefits). It is important to minimize adverse reactions and maximize efficacy. To obtain a better therapeutic response, patients should understand their medication and cooperate with the treatment.
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产地国家: 日本
原产地英文商品名:
Flutiform Aerosol（フルティフォーム）50mcg/doses Inhaler 56doses Inhaler
原产地英文药品名:
Fluticasone Propionate/Formoterol Fumarate Hydrate
中文参考商品译名:
Flutiform（フルティフォーム）50微克/剂量吸入用 56剂量吸入用
中文参考药品译名:
丙酸氟替卡松/富马酸福莫特罗水合物
生产厂家中文参考译名:
杏林药业
生产厂家英文名:
Kyorin Pharmacetical Co

----------------------------------------------------
产地国家: 日本
原产地英文商品名:
Flutiform Aerosol（フルティフォーム）50mcg/doses Inhaler 120doses Inhaler
原产地英文药品名:
Fluticasone Propionate/Formoterol Fumarate Hydrate
中文参考商品译名:
Flutiform（フルティフォーム）50微克/剂量吸入用 120剂量吸入用
中文参考药品译名:
丙酸氟替卡松/富马酸福莫特罗水合物
生产厂家中文参考译名:
杏林药业
生产厂家英文名:
Kyorin Pharmacetical Co

----------------------------------------------------
产地国家: 日本
原产地英文商品名:
Flutiform Aerosol（フルティフォーム）125mcg/doses Inhaler  120doses Inhaler
原产地英文药品名:
Fluticasone Propionate/Formoterol Fumarate Hydrate
中文参考商品译名:
Flutiform（フルティフォーム）125微克/剂量吸入用 120剂量吸入用
中文参考药品译名:
丙酸氟替卡松/富马酸福莫特罗水合物
生产厂家中文参考译名:
杏林药业
生产厂家英文名:
Kyorin Pharmacetical Co

----------------------------------------------------
产地国家: 日本
原产地英文商品名:
Flutiform Aerosol（フルティフォーム）125mcg/doses Inhaler  56doses Inhaler
原产地英文药品名:
Fluticasone Propionate/Formoterol Fumarate Hydrate
中文参考商品译名:
Flutiform（フルティフォーム）125微克/剂量吸入用 56剂量吸入用
中文参考药品译名:
丙酸氟替卡松/富马酸福莫特罗水合物
生产厂家中文参考译名:
杏林药业
生产厂家英文名:
Kyorin Pharmacetical Co