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ABILIFY injection(阿立哌唑缓释注射悬浮液)

2015-08-31 14:09:11  作者:新特药房  来源:互联网  浏览次数:107  文字大小:【】【】【
简介: 英文药名:ABILIFY prolonged release aqueous suspension for IM injection(Aripiprazole Hydrate) 中文药名:阿立哌注射唑缓释水悬浮液 生产厂家:大冢制药类别名称可持续发展抗精神病药商標名 A ...

英文药名:ABILIFY prolonged release aqueous suspension for IM injection(Aripiprazole Hydrate)

中文药名:阿立哌缓释注射悬浮液

生产厂家:大冢制药

エビリファイ持続性水懸筋注用300mg/エビリファイ持続性水懸筋注用400mg

类别名称
可持续发展抗精神病药
商標名
ABILIFY prolonged release aqueous suspension for IM injection
一般名:
アリピプラゾール水和物[Aripiprazole Hydrate (JAN)]
化学名:
7-{4-[4-(2,3-Dichlorophenyl)piperazin-1-yl]butoxy}-3,4-dihydroquinolin-2(1H)-one monohydrate
構造式

分子式:
C23H27Cl2N3O2・H2O
分子量:
466.40
性 状:
是一种白色结晶。四氢呋喃,乙酸(100),并易溶于苄醇,并易溶略微二甲基亚砜,乙醇(99.5)是微溶的,并且极微溶于甲醇,和几乎不溶于水。
审批条件
在制定药品风险管理计划,要正确实现
适应症
用于各类精神病
剂量和给药方法
通常给药一次的成人臀部肌肉注射一次400毫克〜4周为阿立哌唑。此外,症状,减少到单剂量为300mg取决于耐受性
包装
肌肉注射
:300毫克
1小瓶(悬浮液的日局水注射液2ml和PSF瓶适配器(医疗器械通知号码:11B1X10017000015)安装一个)


肌肉注射:400毫克
1小瓶(悬浮液的日局水注射液2ml和PSF瓶适配器(医疗器械通知号码:11B1X10017000015)安装一个)

生产厂商:大冢制药有限公司
原处方附件:http://www.kegg.jp/medicus-bin/japic_med?japic_code=00065428
阿立哌唑(Abilify)是一种新型的非典型抗精神病药物,对多巴胺D2受体具有部分激动作用,通过激动D2受体,提高额叶区不足的多巴胺功能,改善阴性症状,并且减低中脑-边缘系统通路过高的多巴胺功能以改善阳性症状。
ABILIFY prolonged release aqueous suspension for IM injection 300 mg(エビリファイ持続性水懸筋注用300mg)
Brand name : ABILIFY prolonged release aqueous suspension for IM injection 300 mg
 Active ingredient: Aripiprazole hydrate
 Dosage form: injection
 Print on wrapping:
ABILIFY prolonged release aqueous suspension for IM injection 400 mg(エビリファイ持続性水懸筋注用400mg)
Brand name
: ABILIFY prolonged release aqueous suspension for IM injection 400 mg
 Active ingredient: Aripiprazole hydrate
 Dosage form: injection
 Print on wrapping:
Effects of this medicine
This medicine acts on receptors for neurotransmitters such as dopamine in the brain, to suppress symptoms such as hallucinations and delusions, stabilize unstable mental status, and improve symptoms such as lack of motivation and loss of interest.
It is usually used in the treatment of schizophrenia.
Before using this medicine, be sure to tell your doctor and pharmacist
•If you have previously experienced any allergic reactions (itch, rash, etc.) to any medicines.
If you have diabetes or if you or your family has a history of diabetes.
If you have: hepatic disorder, cardiovascular disease or hypotension, convulsive disease such as epilepsy or a history thereof, suicidal attempt or suicidal ideation.
•If you are pregnant or breastfeeding.
•If you are taking any other medicinal products. (Some medicines may interact to enhance or diminish medicinal effects. Beware of over-the-counter medicines and dietary supplements as well as other prescription medicines.)
Dosing schedule (How to take this medicine)
•Your dosing schedule prescribed by your doctor is <<to be written by a healthcare professional>>
•In general, this medicine is administered intramuscularly into the gluteal muscle once every 4 weeks.
•This medicine may be administered over a long period according to your response to the treatment.
•Ask your doctor regarding the frequency of your injections.
Precautions while taking this medicine
•This medicine may cause sleepiness; decreased attentiveness, concentration and reflex movements. Avoid operating dangerous machinery such as driving a car.
•Alcohol may intensify the therapeutic effects of the medicine. Be careful when drinking alcohol.
•Because the effect of this medicine lasts one month after administration, you need to beware of its adverse effects or the use of other medicines until this medicine has been completely eliminated from your body. If you visit other medical institutions, tell your doctor or pharmacist that you are using this medicine.
Possible adverse reactions to this medicine
The most commonly reported adverse reactions include injection site pain, injection site erythema, injection site induration, injection site swelling, weight increase, and akathisia (restlessness). If any of these symptoms occur, consult with your doctor or pharmacist.
The symptoms described below are rarely seen as initial symptoms of the adverse reactions indicated in brackets. If any of these symptoms occur, see your doctor immediately.
•dry mouth, excessive intake of water, increased urine output [diabetic ketoacidosis, diabetic coma]
•being silent without moving, muscle stiffness, sudden fever [neuroleptic malignant syndrome]
•moving the tongue, putting the tongue out and pulling it back in, continual movement of the mouth appearing to chew something [tardive dyskinesia]
•nausea, vomiting, constipation, intense abdominal pain [paralytic ileus]
•weakness, muscle pain, reddish brown urine [rhabdomyolysis]
The above symptoms do not describe all the adverse reactions to this medicine. Consult with your doctor or pharmacist if you notice any symptoms of concern other than those listed above.
Otsuka Pharmaceutical Co., Ltd.Injection
Published: 5/2015
The information on this sheet is based on approvals granted by the Japanese regulatory authority. Approval details may vary by country. Medicines have adverse reactions (risks) as well as efficacies (benefits). It is important to minimize adverse reactions and maximize efficacy. To obtain a better therapeutic response, patients should understand their medication and cooperate with the treatment.

责任编辑:admin


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