英文药名: Suprax (cefixime suspension)
中文药名: 头孢克肟口服悬浮液
药品名称
【通用名称】头孢克肟
【英文名称】Cefixime
【成份／规格】头孢克肟。头孢克肟悬浮液100mg/5ml。头孢克肟片 50mg;100mg;200mg;400mg。
药理毒理
对革兰氏阳性菌和革兰氏阴性菌均有较广泛的抗菌作用，特别是对革兰氏阳性菌中的链球菌属、肺炎球菌、革兰氏阴性菌中的淋球菌、伯雷汉氏菌属、大肠杆菌、沙雷氏杆菌属、克雷白氏菌属、变形杆菌属、流感杆菌等较其它口服头孢类有较强的抗菌能力，其作用方式为杀菌。
由于本品对各种细菌所产生的β-内酰胺酶极其稳定，因而对产生β-内酰胺酶的细菌也具有优异的抗菌力。
本品的作用机制主要是阻止细菌细胞壁的合成。
适应症
广谱抗菌素。对链球菌属、肺炎球菌、淋球菌、伯雷汉氏菌属、大肠杆菌、沙雷氏杆菌属、克雷白氏杆菌属、变形杆菌属、流感杆菌所引起的感染症有效。主要用于治疗支气管炎、支气管扩张合并感染、慢性呼吸道疾患继发感染、肺炎、肾盂肾炎、膀胱炎、淋菌性尿道炎、胆囊炎、胆管炎、猩红热、中耳炎、副鼻窦炎。
用法用量
口服。成人和体重30公斤以上的儿童一次50～100mg，一日2次。重症可增加到一次0.2g，一日2次。
任何疑问，请遵医嘱！
不良反应
主要为腹泻、粪便异常、头疼、恶心、腹痛、皮疹等，极少数患者GPT、GOT升高。
禁忌
对本品或头孢菌素类抗菌素有过敏史者禁用。
注意事项
对青霉素过敏者、过敏体质的患者、高度肾功能损害的患者、对不能很好进食或非经口摄取营养者、高龄者、恶液质等患者、孕妇、新生儿慎用。
Suprax is a cephalosporin antibiotic which fights bacterial infections in the body. Suprax is inappropriate for infections caused by other sources such as fungus or viruses. Suprax can be prescribed generically as cefixime. Suprax is commonly used to treat bacterial infections such as tonsillitis, ear and skin infections, gonorrhea, bronchitis, urinary tract infections, and sometimes infection in the mouth. Patients should complete the entire round of antibiotics even if they start to feel better and become asymptomatic, as this is not an indication that the infection has cleared. Stopping Suprax prematurely may result in the return of the infection.
Suprax should not be prescribed without an accurate medical history. Not all patients will be able to take Suprax without aggravating existing conditions. Patients with additional medical conditions may not be able to take Suprax or may require careful monitoring while undergoing drug therapy with this medication, depending on the condition and the severity of the condition. Patients with a history of kidney disease or a previous allergic reaction to penicillin or other cephalosporin antibiotic fall into this category.
Suprax is not expected to cause harm or birth defects in unborn babies and has been granted a pregnancy risk rating of category B by the American Food and Drug Administration. Suprax has not been determined to pass through the mother’s breast milk, nor has it been determined safe for a breast feeding infant. Women who are pregnant should calculate the risks and the benefits of taking Suprax while women who are nursing should avoid taking this medication.
Suprax is associated with side effects. Severe side effects may occur in patients who have no previous experience with cephalosporin antibiotics. Allergic reactions (difficulty breathing, facial swelling, and hives) severe nausea, vomiting, diarrhea, or dehydration caused by vomiting or diarrhea, red or peeling and blistering rash, unexplained bleeding, unusual bruising, and mucous or blood in the stools all require immediate emergency medical attention as these are signs of adverse health effects associated with Suprax.
Less serious and mild side effects are much more common and may include symptoms such as mild nausea or diarrhea, and a vaginal or oral yeast infection. Side effects such as these do not need to medical attention beyond treating the yeast infection and reporting the symptoms to the prescribing physician. Many physicians recommend eating a daily serving of yogurt to avoid yeast infection, especially for women.
Suprax should be taken on a regular schedule which is evenly spaced to maintain a specific level of medication in the bloodstream, although patients may forget a dose form time to time. Forgotten or missed doses can be taken when remembered unless it is almost time for the next scheduled dose. If it is almost time for the next dose, the missed dose can either be skipped, or the patient can take the dose and adjust the remaining doses to maintain an appropriate schedule. Taking double doses or taking too much medication can cause an overdose, which can lead to health complications such as abdominal pain and cramping, nausea, vomiting, diarrhea, and dehydration.
Patients should be warned not to mix certain medications and never to take additional medications including over the counter, prescription, or herbal medications without first consulting with the prescribing physician or pharmacist. Drug interactions can either cause serious health complications or can create ineffective medication. Medications with known interactions with Suprax include probenecid, blood thinners such as warfarin, as well as additional antibiotics. Physicians should always assess a complete medical history and current medication list prior to prescribing Suprax.
温馨提示：Appears to be powder in bottle to be reconstituted with water when ready to use。是干粉包装，用之前需水稀释
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产地国家: 英国
原产地英文商品名:
SUPRAX Powder for Paediatric Oral Suspension 100ml
原产地英文药品名:
CEFIXIME
中文参考商品译名:
SUPRAX 剂粉的口服混悬液(儿童服用)100毫升
中文参考药品译名:
头孢克肟
生产厂家中文参考译名:
赛诺菲安万特
生产厂家英文名:
Sanofi Aventis
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产地国家: 英国
原产地英文商品名:
SUPRAX Powder for Paediatric Oral Suspension 50ml
原产地英文药品名:
CEFIXIME
中文参考商品译名:
SUPRAX 剂粉的口服混悬液(儿童服用)50毫升
中文参考药品译名:
头孢克肟
生产厂家中文参考译名:
赛诺菲安万特
生产厂家英文名:
Sanofi Aventis