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药品名称：氢溴酸替格列汀片
英文名称：TENELIA（Teneligliptin Hydrobromide Hydrate Tablets）
日文药名：テネリア錠
适应症：2型糖尿病
原研企业：日本三菱田边制药，2012年日本上市
作用机制：DPP-Ⅳ抑制剂
テネリア錠 20mg
商標名
TENELIA Tablets 20mg
一般名
テネリグリプチン臭化水素酸塩水和物
(Teneligliptin Hydrobromide Hydrate)
化学名
{(2S, 4S )-4-[4-(3-Methyl-1-phenyl-1H -pyrazol-5-yl)piperazin-1-yl] pyrrolidin-2-yl} (1,3-thiazolidin-3-yl)methanone hemipentahydrobromide hydrate
分子式
分子量
628.86（無水物）
構造式
性状
它是一种白色粉末。
它易溶于水，所以容易给微溶于甲醇和少量溶于乙醇（99.5），微溶于乙腈。
熔点
大约201℃（分解）
效果或疗效
*2型糖尿病
剂量和用法
成年人每天一次20毫克（口服）。注意，如果效果不明显，可提高每次，40mg，同时观察经过充分。
包装
テネリア錠20mg：100錠（10錠×10）
テネリア錠20mg：140錠（14錠×10）
テネリア錠20mg：500錠（10錠×50）
テネリア錠20mg：500錠（バラ）
製造販売元
田辺三菱製薬株式会社
完整资料附件：http://www.info.pmda.go.jp/go/pack/3969015F1029_2_06/
Tenelia (Teneligliptin Hydrobromide Hydreate) - 20mg
Please note: The product packaging is available in Japanese language only.
What is Tenelia?
Tenelia containing the active ingredient teneligliptin hydrobromide hydreate belongs to a class of medications called dipeptidyl peptidase 4 (DPP4) inhibitors. The medication is a new class of antidiabetic medication used in the treatment of type 2 diabetes in patients who do not show sufficient improvement achieved through diet control, a proper exercise program and the use of other medications. The drug works by increasing insulin release and suppressing glucagen release to lower blood glucose levels.
How is Tenelia used?
Tenelia is usually taken orally once per day or as directed by a doctor. The tablets can be taken with or without food but should be taken with some water. Contact a doctor for correct dosage as it will depend on the patient�s condition and their response to the therapy. The maximum recommended dosage is 40mg every 24 hours.
Adverse effects
Patients taking Tenelia may encounter unwanted side effects such as:
Constipation
Stomach pain
Nausea
Hypoglycemia
Eczema
Dermatitis
Tremors
Cold sweat
Contact a doctor immediately should side effects persist or worsen.
Warnings
Immediately proceed to your nearest emergency department if you suffer an allergic reaction. Symptoms usually associated with such a reaction include difficulty breathing or swallowing, chest tightness, swelling, skin rashes, and hives.
Tenelia is not always suitable for all patients. Always consult your health care provider prior to using this medication if you are pregnant, breastfeeding, trying to conceive, using any other medication (prescription or non-prescription), using any herbal products or supplements, or if you have any allergies or other health problems.
The correct dosage and prescription commonly depend on the patient and the condition being treated. Do not adjust your dosage without the approval of your health care provider. This product is only for use as prescribed and instructed.
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