部分中文PLAQUENIL信息资料(仅供参考)
【商品名】Plaquenil(必赖克瘘锭)
【学名】Hydroxychloroquine Sulfate
【适应症】全身性红斑性狼疮、慢性多形日光疹、慢性风湿性关节炎、镰状疟原虫和间日疟原虫引起之疟疾。
【用法】口服
【用量】2.325-3.875 mg∕kg,分1-2次服用。
【副作用】疲倦、头晕、肤色变黑、色素沉淀、发色变淡、视网膜发炎。
【家长请注意】:每3个月应定期带孩子至眼科检查「视野」领域。
【医师的叮咛】:使用Plaquenil其目的在于减少红斑性狼疮的活性,不仅如此,还减少类固醇使用量。
倘若患者只有关节炎、掉发等问题,那么,只需使用「抗疟疾药」与「非类固醇抗发炎药物」。
Plaquenil®(HYDROXYCHLOROQUINE SULFATE, USP)
Generic Name and Formulations:
Hydroxychloroquine sulfate 200mg; tabs.
Company:
Covis Pharmaceuticals, Inc.
Indications for PLAQUENIL:
Refractory rheumatoid arthritis or lupus erythematosus.
Adult Dose for PLAQUENIL:
Rheumatoid arthritis: initially 400–600mg daily with food or milk. Lupus: initially 400mg 1–2 times daily. Maintenance for both: 200–400mg daily.
Children's Dose for PLAQUENIL:
Not recommended.
Pharmacological Class:
DMARD (aminoquinoline).
Contraindications:
Long-term use in children. Retinal or visual field changes.
Warnings/Precautions:
Be fully familiar with this product's toxicity before use. Psoriasis. Porphyria. Hepatic dysfunction. Alcoholism. G6PD deficiency. Monitor ocular function, reflexes, and blood in chronic use. Discontinue if blood dyscrasias, visual symptoms or muscular weakness occur or if ineffective after 6 months in rheumatoid arthritis. Pregnancy: not recommended. Nursing mothers.
Interactions:
Avoid other hepatotoxic or dermatotoxic drugs.
Adverse Reactions:
Irreversible retinopathy, blurred vision, corneal edema or deposits, visual field defects, irritability, neuromuscular dysfunction, hair bleaching, alopecia, pruritus, skin pigmentation, rash, blood dyscrasias, anorexia, nausea, weight loss.
How Supplied:
Tabs—100
200毫克/片 100片/瓶