英文药名：SUINY Tab（Anagliptin）
中文药名：阿格列汀片
生产厂家：三和化学
药品介绍
选择性DPP-4抑制剂 -2型糖尿病治疗药物-
批准上市日期：2012年11月
商標名
SUINY Tab.100mg
一般名
Anagliptin アナグリプチン
化学名
N-[2-({2-[(2S)-2-Cyanopyrrolidin-1-yl]-2-oxoethyl}amino)-2-methylpropyl]-2-methylpyrazolo[1,5-a]pyrimidine-6-carboxamide
分子式
C19H25N7O2
分子量
383.45
構造式
性状
Anaguripuchin是一种结晶性粉末或白色的结晶或淡黄色。它非常易溶于水，易溶于甲醇或乙腈，易微溶于乙醇（99.5），微溶于2 - 丙醇，和极微溶于己烷。
融点
117～119℃
分配係数
0.46（1 - 辛醇/水）
适用症：
适用于治疗2型糖尿病
剂量与用法：
口服，每日服用两次，每次100毫克/片。
包装
100錠（PTP10錠×10）、140錠（PTP14錠×10）、500錠（PTP10錠×50、バラ）
生产商
三和化学研究所
SUINY Tablets 100mg（スイニー錠100mg）
Brand name : SUINY Tablets 100mg
Active ingredient: Anagliptin
Dosage form: pale yellow tablet with a split line, diameter: 8.1 mm, thickness: 3.4 mm
Print on wrapping: スイニー100mg, スイニー, 100, 糖尿病用薬, SUINY100, Sc132
Effects of this medicine
This medicine inhibits the enzyme (DPP-4) which degrades incretin, a hormone acting to maintain constant blood glucose level. It enhances insulin secretion and suppresses glucagon secretion to improve blood glucose control when blood glucose level is elevated.
It is usually used for the treatment of type 2 diabetes mellitus.
Before using this medicine, be sure to tell your doctor and pharmacist
If you have previously experienced any allergic reactions (itch, rash, etc.) to any medicines.
If you have: ketosis, diabetic coma or precoma, type 1 diabetes mellitus, infection or injury.
If you are just after/before having surgery.
If you are pregnant or breastfeeding.
If you are taking any other medicinal products. (Some medicines may interact to enhance or diminish medicinal effects. Beware of over-the-counter medicines and dietary supplements as well as other prescription medicines.)
Dosing schedule (How to take this medicine)
Your dosing schedule prescribed by your doctor is <<to be written by a healthcare professional>>
In general, for adults, take 1 tablet (100 mg of the active ingredient) at a time, twice a day, in the morning and in the evening. If the effect is insufficient, a dose may be increased up to 2 tablets (200 mg) at a time, adequately monitoring the condition. If you have severe renal dysfunction, a dose may be decreased appropriately. Strictly follow the instructions.
If you miss a dose, take a dose as soon as possible. If it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. You should never take two doses at one time.
If you accidentally take more than your prescribed dose, consult with your doctor or pharmacist.
Do not stop taking this medicine unless your doctor instructs you to do so.
Precautions while taking this medicine
Strictly follow the instructions on dietary/exercise therapy.
Pay close attention that this medicine may cause hypoglycemia.
If episode of hypoglycemia is occurred, take an adequate amount of sugar (sugar, glucose, soft drink, etc.). If you take an alpha-glucosidase inhibitor (medicines which delay absorption of sugar such as miglitol or acarbose) simultaneously taking this medicine, and episode of hypoglycemia is occurred, take glucose.
This medicine may cause hypoglycemic symptoms. Pay close attention when you perform dangerous operations such as driving a car, operating machinery or working at heights.
Possible adverse reactions to this medicine
The most commonly reported adverse reactions include constipation, hypoglycemia, rash and itch. If any of these symptoms occur, consult with your doctor or pharmacist.
The symptoms described below are rarely seen as initial symptoms of the adverse reactions indicated in brackets. If any of these symptoms occur, stop taking this medicine and see your doctor immediately.
cold sweat, a sense of hunger, tremor of limbs [hypoglycemia]
stoppage of stool. abdominal pain, abdomen enlarged feeling [intestinal obstruction]
The above symptoms do not describe all the adverse reactions to this medicine. Consult with your doctor or pharmacist if you notice any symptoms of concern other than those listed above.
Storage conditions and other information
Keep out of the reach of children. Store away from direct sunlight, heat and moisture.
Discard the remainder. Do not store them.
Kowa Co., Ltd. Internal
Revised: 7/2015
The information on this sheet is based on approvals granted by the Japanese regulatory authority. Approval details may vary by country. Medicines have adverse reactions (risks) as well as efficacies (benefits). It is important to minimize adverse reactions and maximize efficacy. To obtain a better therapeutic response, patients should understand their medication and cooperate with the treatment.
http://www.info.pmda.go.jp/go/pack/3969016F1023_1_06/