英文药名：Kylit injection 5％（Xylitol）

中文药名：木糖醇注射液5％

生产厂家：大冢制药
类别名称
五炭糖 糖質補給剤
欧文商標名
Kylit injection 5％
一般名：
キシリトール（Xylitol）　
構造式：

化学名：
meso -Xylitol
分子式：
C5H12O5
分子量：
152.15
融点：
93.0 ～ 95.0℃
性状
白色结晶或粉末，无臭，味微甜。
易溶于水，微溶于乙醇（95）。它是吸湿的。
操作注意事项
1. 直针刺伤的事情〇橡胶塞标志。而针头刺入斜穿透容器颈部可能导致泄漏。
2. 软袋产品无法通过使用连接管原理的串联系统给药。
3. 那些和液体水滴观察到的是有色的或混浊在包装中的内容不应被使用。
4. 容器的液体规模被用作粗略指导。
药效药理
能源供应
木糖醇在体内代谢，而是被积累作为部分糖原很大程度上被快速利用作为能源和排泄作为二氧化碳。
胰岛素独立性
木糖醇独立地与胰岛素作为碳水化合物利用，这不是对血糖水平的影响较小，可用于糖尿病患者。
抗酮作用
木糖醇具有防酮作用，以校正酮症
适应症:
用于糖尿病人补充能量和体液，调整代谢，减轻症状，消除血稠症；也可用于各种糖代谢障碍时外科手术麻醉的糖类补给。
用法用量:
通常静脉注射或静脉滴注分为成人每日2?50克1至数次。
此外，增加或减少取决于患者的年龄和症状。然而，这将是直到每日剂量100克木糖醇。
当分配滴注，其作为木糖醇速度，少0.3克/kg/小时
禁忌:
1.对本品过敏者禁用。
2.胰岛素诱发的低血糖症患者禁用。
注意事项:
（1）滴注速度:木糖醇注射液滴注速度应更加缓慢。
（2）肾功能不全者禁用。
不良反应:
滴注速度稍快可引起代谢性酸中毒，肾脏，大脑功能损伤等严重反应。
相互作用:
尚不明确。
包装规格
木糖醇注5％
300毫升*20袋[软袋]
500毫升*20袋[软袋]
木糖醇注20％
20毫升*50管 塑料安瓿
生产商：
大冢制药有限公司
附原处方：
http://www.kegg.jp/medicus-bin/japic_med?japic_code=00058239
http://www.kegg.jp/medicus-bin/japic_med?japic_code=00049906
http://www.info.pmda.go.jp/go/pack/3234400H2045_1_04/
Therapeutic category name
Brand Name
Crisp Note 5% (500mL bag)
Composition
This drug is injectable solution containing the following components in one container (500mL).
Xylitol
25g / 500mL (5%)
Amount of heat
100kcal / 500mL
Contraindication
Hypotonic dehydration of the patient [this disease is caused by the fact that the osmotic pressure of the serum by the deficiency of sodium is hypotonic. Administration of this drug in such patients, it means to increase the water content, there is a risk that symptoms worse. ]
Efficacy or effect
Water and energy supply at the time of diabetes and diabetic condition
As xylitol, usually, intravenous injection or intravenous drip infusion is divided into per day for adults 2 ~ 50g 1 to several times.
In addition, it will be increased or decreased depending on the patient's age and symptoms. However, it will be until the daily dose 100g as xylitol.
When dispensing drip infusion, its velocity as xylitol, be less 0.3g / kg / hr.
Careful administration
Suitable moisture in diabetes insipidus patient [this disease, it is necessary to manage the electrolyte, affecting the electrolyte or the like by the administration of this drug, there is a risk that symptoms worse. ]
Liver failure, patients with renal failure [mass rapid administration to and liver failure of xylitol, there is a possibility that appears renal failure. ]
Pharmacology
Energy supply
Xylitol is metabolized in the body, but is stored as part of glycogen, the majority are utilized immediately as an energy source, 7-14, which is excreted as carbon dioxide).
Insulin independence
Xylitol is independently utilized with insulin as carbohydrates, no little effect on blood glucose, 8, 10, 15 to 17 can be used for diabetic patients).
Anti-ketone action
Xylitol has a anti-ketone action, 10, 18 and 20 to correct the ketosis).
The physicochemical knowledge of active ingredient
Generic name
Xylitol (Xylitol)
Chemical name
meso -Xylitol
Molecular formula
C5H12O5
Molecular weight
152.15
Melting point
93.0 ~ 95.0 ℃
Behavior
A white crystal or powder, no smell, taste sweet.
It is very soluble in water, slightly soluble in ethanol (95). It is hygroscopic.