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当前位置:药品说明书与价格首页 >> 抗感染类 >> 药品目录 >> 抗生素类 >> 青霉素类 >> PIPERACILLIN Injection(哌拉西林钠注射液)

PIPERACILLIN Injection(哌拉西林钠注射液)

2016-09-29 06:47:20  作者:新特药房  来源:互联网  浏览次数:32  文字大小:【】【】【
简介: 英文药名:PIPERACILLIN Injection(Piperacillin Sodium) 中文药名:哌拉西林钠注射液 生产厂家:Nichi-IKO药业治疗类别名称合成青霉素制剂欧文商標名 PIPERACILLIN 一般名:ピペラシリンナトリウム( ...

英文药名:PIPERACILLIN Injection(Piperacillin Sodium)

中文药名:哌拉西林钠注射液

生产厂家:Nichi-IKO药业

ピペラシリンナトリウム注射用1g「日医工」/ピペラシリンナトリウム注射用2g「日医工」

治疗类别名称
合成青霉素制剂
欧文商標名
PIPERACILLIN
一般名:
ピペラシリンナトリウム(Piperacillin Sodium)
略号:
PIPC
化学名:
Monosodium(2S ,5R ,6R )-6-{(2R )-2-[(4-ethyl-2,3-dioxopiperazine-1-carbonyl)amino]-2-phenylacetylamino}-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate
構造式:

分子式:
C23H26N5NaO7S
分子量:
539.54
性状:
为白色粉末或质量。
非常易溶于水,易溶于甲醇或乙醇(95),并在乙腈中几乎不溶。
药效药理
革兰氏阳性球菌0.39〜3.13μg/毫升,大肠杆菌,革兰氏阴性杆菌0.78〜6.25μg/ mL,比如变形,防止绿脓杆菌的许多菌株在以下12.5μg/毫升,还肺炎杆菌,沙雷氏菌属,和拟杆菌它显示了羧苄青霉素和磺苄西林的效果。反对青霉素酶相当稳定。作用机制是细菌细胞壁的肽聚糖合成抑制,作用杀菌。
适应症
适用敏感肠杆菌科细菌、铜绿假单胞菌、不动杆菌属所致的败血症、上尿路及复杂性尿路感染、呼吸道感染、胆道感染、腹腔感染、盆腔感染以及皮肤、软组织感染等。哌拉西林与氨基糖苷类联合应用亦可用于有粒细胞减少症免疫缺陷病人的感染。
用法用量
本品可供静脉滴注和静脉注射。成人中度感染一日8g,分2次静脉滴注;严重感染一次 3~4g,每4~6小时静脉滴注或注射。一日总剂量不超过24g。婴幼儿和12岁以下儿童的剂量为每日按体重100~200mg/kg。新生儿体重低于2kg者,出生后第1周每12小时50mg/kg,静脉滴注;第2周起50mg/kg,每8小时1次。新生儿体重2kg以上者出生后第1周每8小时50mg/kg,静脉滴注;1周以上者每6小时50mg/kg。
包装规格
注射剂
1克×10瓶

2克×10瓶

生产商:Nichi-iko Pharmaceutical Co
完整处方来源:http://www.info.pmda.go.jp/go/pack/6131403D1217_1_04/
PIPERACILLIN Injection(Piperacillin sodium)
PIPERACILLIN Injection 1g "Nichiiko"(ピペラシリンナトリウム注射用1g「日医工」) 
Brand name : PIPERACILLIN Injection 1g "Nichiiko"
 Active ingredient: Piperacillin sodium
 Dosage form: injection
 Print on wrapping: 
PIPERACILLIN Injection 2g "Nichiiko"(ピペラシリンナトリウム注射用2g「日医工」) 
Brand name : PIPERACILLIN Injection 2g "Nichiiko"
 Active ingredient: Piperacillin sodium
 Dosage form: injection
 Print on wrapping:
Effects of this medicine
This medicine is a penicillin antibiotic agent. It inhibits the synthesis of bacterial cell wall to show bactericidal effect.
It is usually used to treat various infections such as blood borne/respiratory/urinary tract/biliary tract/gynecologic infection. 
Before using this medicine, be sure to tell your doctor and pharmacist
•If you have previously experienced any allergic reactions (itch, rash, etc.) to any medicines. If you have infectious mononucleosis.
•If you are pregnant or breastfeeding.
•If you are taking any other medicinal products. (Some medicines may interact to enhance or diminish medicinal effects. Beware of over-the-counter medicines and dietary supplements as well as other prescription medicines.)
Dosing schedule (How to take this medicine)
•Your dosing schedule prescribed by your doctor is <<to be written by a healthcare professional>>
•In general, for adults, inject intravenously, by intravenous infusion or intramuscularly 2 to 4 times a day. In general, for children, inject intravenously or by intravenous infusion 2 to 4 times a day.
•The treatment duration is determined according to symptoms of the patients.
Precautions while taking this medicine
•This medicine may effect on laboratory value. When you take labratory test, inform your doctor that you are using this medicine.
Possible adverse reactions to this medicine
The most commonly reported adverse reactions include fever, rash, itch and nausea/vomiting. If any of these symptoms occur, consult with your doctor or pharmacist.
The symptoms described below are rarely seen as initial symptoms of the adverse reactions indicated in brackets. If any of these symptoms occur, stop taking this medicine and see your doctor immediately.
•respiratory distress, itch, pale face [shock, anaphylaxis]
•high fever, bloodshot eyes, general malaise [toxic epidermal necrolysis, mucocutaneous-ocular syndrome, acute diffuse eruptive pustulosis]
•decreased urine output, edema of limbs/face, fever [severe renal disorder such as acute renal failure and interstitial nephritis]
•general malaise, high fever, gum bleeding [pancytopenia, agranulocytosis, thrombocytopenia, hemolytic anemia ]
•frequent diarrhea, abdominal pain, fever [severe colitis such as pseudomembranous colitis accompanied with bloody stool]
The above symptoms do not describe all the adverse reactions to this medicine. Consult with your doctor or pharmacist if you notice any symptoms of concern other than those listed above.
Nichi-iko Pharmaceutical Co.,LtdInjection
Revised: 1/2016
The information on this sheet is based on approvals granted by the Japanese regulatory authority. Approval details may vary by country. Medicines have adverse reactions (risks) as well as efficacies (benefits). It is important to minimize adverse reactions and maximize efficacy. To obtain a better therapeutic response, patients should understand their medication and cooperate with the treatment.

责任编辑:admin


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