[通用药名]基因重组人生长激素　
[药品成分]本品是由191个氨基酸残基或N端有一甲硫氨酸的192个氨基酸残基组成的蛋白。　
[作用与用途]本品具有与人体生长激素同等的作用，即能促进骨骼、内脏和全身生长，促进蛋白质合成，影响脂肪和矿物质代谢，在人体生长发育中起着关键性作用。皮下注射约80％被吸收，5小时后达高峰血浓度，t1/2约4小时。主要用于内源性脑垂体生长激素分泌不足而引起的生长障碍、躯体矮小的侏儒症、短小病患儿。此外，尚可用于治疗烧伤、骨折、创伤、出血性溃疡、组织坏死、肌肉萎缩症、骨质疏松等疾病。
[用法与用量]本品给药剂量个体差异很大，采用肌内注射或皮下注射，一般用量为每周0．5—0．7单位／kg或每周12单位／m2，分6—7次给药。
[注意事项]偶可引进皮肤过敏、注射部位发红和皮下脂肪萎缩、氨基转移酶升高、呕吐及腹痛等。
1．肿瘤患者、糖尿病患者、颅内进行性损伤者禁用。
2. 对脑肿瘤的垂体抹儒病者、心脏或肾脏病者、孕妇和哺乳妇女等慎用。
3．使用前，需对脑垂体功能作详细检查，准确诊断后才能应用。
4．应临用时配制，用注射用水溶解，轻轻摇动，切勿振荡，以免变性。

Information on Eutropin

Eutropin is a recombinant human growth hormone from yeast.
Composition
Each vial contains 4 IU of Recombinant Human Growth Hormone (somatropin).
Indication
Growth failure or short stature due to growth hormone deficiency;Expected possible candidates against aging, osteoporosis, wounds, infertility and bums.
Characteristics
Same amino acid sequence with authentic human growth hormone through hydrolysis of N-terminal methionyl residue  by LG’s proprietary aminopeptidase.
Excellent physico-chemical properties  and low immunogenicity.
Indication
Short stature due to: Endogenous Growth Hormone Deficiency in children, Turner's Syndrome

Dosage
Short stature due to endogenous GHD    0.5~0.7IU/kg/week or daily 12 IU/m2 in 6~7 divided doses by SC.
Short stature due to Turner's syndrome   1IU/kg in 6~7 divided doses weekly by SC or IM.
Shelf Life
18 months   After reconstitution use within 36 hours
Storage
Store in hermetic container at 2~8°C. Do not freeze.
Availability
4 IU/vial x 1,5,10 vials/pack (with solvent)
Launched  February, 1993

原产地英文商品名:	EUTROPIN Inj 4iu Vial
原产地英文药品名:	SOMATROPIN RECOMBINANT
中文参考商品译名:	EUTROPIN 4单位/支
中文参考药品译名:	重组人生长激素
临床试验期:	完成
中文适应病症参考翻译1:	儿童内源性生长激素缺乏症
中文适应病症参考翻译2:	特纳综合征
生产厂家中文参考译名:	霍夫曼
生产厂家英文名:	Hoffmann