中文名称: 美替诺龙醋酸酯

英文名称: Methenolone acetate

中文同义词: 美替诺龙醋酸酯;17β-羟基-1-甲基-5α-雄甾-1-烯-3-酮-17-醋酸酯

来源
美替诺龙来源于人体内最强的雄性激素双氢睾酮（DHT）。将DHT分子略作修改就成了美替诺龙由于这个关系，美替诺龙不能转化为雌激素，因此使用美替诺龙没有雌化的危险。
医学上，美替诺龙被尝试用于治疗贫血症、硬皮病和类风湿治疗中辅助防止蛋白质、骨质流失及皮肤硬化等。由于美替诺龙副作用较小，而且没有雌激素作用，所以往往能取得较好疗效的同时又不会引起令人不待见的雌化副作用。
虽然美替诺龙脱胎于最强的雄性激素DHT，但它本身的雄性激素能力并不强，仅为原始睾酮的44-57%，且完全不转雌没有雌化风险，所以美替诺龙可以说是副作用很小的类固醇，要比较的话，它的副作用低于宝丹酮。

性能
美替诺龙与睾酮的作用原理大致相同，但美替诺龙的合成代谢能力相比于原始睾酮有所降低，大约是睾酮的88%合成代谢能力比较温和，不会有如DECA似的猛烈膨胀，然而它的雄性激素能力下降更多，只有原始睾酮的44-57%因此副作用小得多。

用途
美替诺龙作为很“绅士”的类固醇，并不是增肌的猛药，由于他副作用小可长时间使用，而且无转雌的问题，所以它常常被用在竞技健美上，作为可以跟曲他雄酮Masteron、群勃龙Trenbolone比肩的备赛佳品。

主要副作用及保护
美替诺龙的副作用较少且轻微，一般来说比宝丹酮的副作用还小。
美替诺龙的雄性激素能力很低，要很大剂量才能引起雄性激素样副作用，如：脱发、痤疮、前列腺肿大等。因此是有脱发、前列腺肿大症状者的佳选。但同时，它的雄性激素能力又不像DECA那么低（睾酮的30%），因此不会像DECA那样引起性欲减退、不举。
另一方面，美替诺龙完全不转雌，因此乳腺肿大发育、储脂、储水这类雌激素副作用完全不会出现。另外美替诺龙还有较弱的抗雌能力。

【原产地英文商品名】PRIMOBOLAN 5mg/tab 100tabs/box
【原产地英文药品名】METHENOLONE ACETATE
【中文参考商品译名】PRIMOBOLAN 5毫克/片 100片/盒
【中文参考药品译名】美替诺龙醋酸酯
【生产厂家中文参考译名】富士制药工业株式会社
【生产厂家英文名】Fuji Pharmaceutical Co., Ltd.

Primobolan
Generic name: methenolone acetate 

Description: This section refers to the oral Primobolan® preparation, which contains the drug methenolone acetate. It is very similar in action to the injectable Primobolan® Depot (methenolone enanthate), but obviously here the drug is designed for oral administration.
 
General information 
This section refers to the oral Primobolan® preparation, which contains the drug methenolone acetate. It is very similar in action to the injectable Primobolan® Depot (methenolone enanthate), but obviously here the drug is designed for oral administration. At one time Schering was in fact also manufacturing an injectable methenolone acetate (Primobolan® acetate, out of manufacture since 1993), which proved to be very useful for pre-contest cutting purposes. This steroid is now gravely missed, as it was once a favorite among European competitors. Although we still have the acetate in oral form, it is a close, but not equal substitute (injection is a much more efficient form of delivery for this steroid).

Methenolone regardless of the ester is a very mild anabolic steroid. The androgenic activity of this compound is considerably low, as are its anabolic properties. One should not expect to achieve great gains in muscle mass with this drug. Instead, Primobolan® is utilized when the athlete has a specific need for a mild anabolic agent, most notably in cutting phases of training. It is also a drug of choice when side effects are a concern. A welcome factor is that Primobolan® is not c17 alpha alkylated as most oral steroid are. Due to the absence of such an alteration, this compound is one of the few commercially produced oral steroids that is not notably stressful to the liver. While liver enzymes values have been affected by this drug in some rare instances, actual damage due to use of this substance is not a documented problem. Unfortunately the 1 alkylation and 17-beta esterification of Primobolan® do not protect the compound very well during first pass however, so much of your initial dose will not make circulation. This is obviously why we need such high daily dose with the oral version of Primobolan®.

Primobolan® will also not aromatize, so estrogen related side effects are of no concern. This is very useful when leading up to a bodybuilding contest, as subcutaneous water retention (due to estrogen) can seriously lessen the look of hardness and definition to the muscles. Non-aromatizing steroids are therefore indispensable to the competitor, helping to bring about a tight, solid build the weeks leading up to a show. And of course without excess estrogen there is little chance of the athlete developing gynecomastia. Likewise there should never be a need for antiestrogen use with this steroid. Primobolan® is also said to have a low impact on endogenous testosterone production. Although this may well be true in small clinical doses, it will not hold true for the bodybuilder. For example, in one stud more than half of the patients receiving only 30-45 mg noted a suppression of gonadotropin levels of 15% to 65% a. This is a dose far less than most bodybuilders would use, and no doubt increasing it would only lead to worse suppression. One would therefore still need a testosterone stimulating drug like HCG or Clomid®/Nolvadex® when concluding a low-dose Primobolan® cycle, unless a deliberately small dose were being used.

It is also important to note that although the androgenic component of Primobolan® is low, side effects are still possible. One may therefore notice oily skin, acne and facial/body hair growth during treatment. Men with a predisposition for hair loss may also find it exacerbates this condition, and wish to avoid this item (nandrolone injectables are a much better choice). While always possible, side effects rarely reach a point where they interfere with the progress of cycle. Primobolan® is clearly one of the milder and safer oral steroids in production. Female athletes, older or more sensitive individuals and steroid beginners will no doubt find this a comfortable steroid to experiment with.

The dosage for men is somewhere in the range of 75-150mg daily. This can obviously be tedious (and costly) if one can only obtain the 5mg tablets from Mexico and S. America. A mild anabolic such as Primobolan® is often used in conjunction with other steroids for optimal effect, so some users find a slightly lower dose effective when stacking. During a dieting or cutting phase, thought to be its primary application, a non-aromatizing androgen like Halotestin® or trenbolone can be added for example. Such combinations would enhance the physique without water retention, and help bring out a harder and more defined look of muscularity. Non-aromatizing androgen/anabolic stacks like this are in fact very popular among competing bodybuilders, as they prove to be Anabolics 2002 quite reliable for rapidly improving the contest form. This compound is also occasionally used with more potent androgens during bulking phases of training. The addition of testosterone, Dianabol or Anadrol 50® would prove effective for instance, although the gains are likely to be accompanied by some level of smoothness due to the added estrogenic component.

Among women, Primobolan® is one of the most popular steroids in use. At a dosage of 50-75mg daily, virilization symptoms are extremely uncommon. One would of course not expect a tremendous amount of muscle mass with this drug, and instead should expect a slow and steady (quality) increase. Some women choose to further add-in other anabolics such as Winstrol® or oxandrolone, in an effort to increase the muscle building effectiveness of a cycle. While both of these compounds are quite tolerable to women, one must be sure not to use too high an accumulated dosage. Troublesome androgenic side effects are always a possibility with steroid use, even with very mild substances. Taken at too high a dosage, these weak anabolics can become a formidable danger to femininity. It would therefore be the best advice not to use the normal dosage range of both, but instead start with a much lower dosage of each steroid to compensate for the other. On the black market Primobolan® orals are popular, but still much less commonly found than the injectable. This is due to the higher cost effectiveness of the injectable, which uses the same active compound but with 100% bioavailability due to the form of administration. When found however the tablets can usually be trusted, provided they are not the 50mg version (discussed below). The price for a single 5mg tablet can be as high as $1 on the US black market, clearly a high expense as the dosage exceeds 100mg daily. The 25mg tabs are much more cost effective when available, priced about 2-3 times higher than the 5mg version but obviously providing five times the volume of drug

プリモボラン錠５mg

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