中文药名: 头孢克肟胶囊

药品名称
【通用名称】头孢克肟
【英文名称】Cefixime
【成份／规格】头孢克肟。头孢克肟悬浮液100mg/5ml。头孢克肟片 50mg;100mg;200mg;400mg。

药理毒理
对革兰氏阳性菌和革兰氏阴性菌均有较广泛的抗菌作用，特别是对革兰氏阳性菌中的链球菌属、肺炎球菌、革兰氏阴性菌中的淋球菌、伯雷汉氏菌属、大肠杆菌、沙雷氏杆菌属、克雷白氏菌属、变形杆菌属、流感杆菌等较其它口服头孢类有较强的抗菌能力，其作用方式为杀菌。 由于本品对各种细菌所产生的β-内酰胺酶极其稳定，因而对产生β-内酰胺酶的细菌也具有优异的抗菌力。 本品的作用机制主要是阻止细菌细胞壁的合成。

适应症
广谱抗菌素。对链球菌属、肺炎球菌、淋球菌、伯雷汉氏菌属、大肠杆菌、沙雷氏杆菌属、克雷白氏杆菌属、变形杆菌属、流感杆菌所引起的感染症有效。主要用于治疗支气管炎、支气管扩张合并感染、慢性呼吸道疾患继发感染、肺炎、肾盂肾炎、膀胱炎、淋菌性尿道炎、胆囊炎、胆管炎、猩红热、中耳炎、副鼻窦炎。

用法用量
口服。成人和体重30公斤以上的儿童一次50～100mg，一日2次。重症可增加到一次0.2g，一日2次。
任何疑问，请遵医嘱！

不良反应
主要为腹泻、粪便异常、头疼、恶心、腹痛、皮疹等，极少数患者GPT、GOT升高。

禁忌
对本品或头孢菌素类抗菌素有过敏史者禁用。

注意事项
对青霉素过敏者、过敏体质的患者、高度肾功能损害的患者、对不能很好进食或非经口摄取营养者、高龄者、恶液质等患者、孕妇、新生儿慎用。

【原产地英文商品名】SUPRAX 50mg/cap 100caps/box
【原产地英文药品名】CEFIXIME
【中文参考商品译名】SUPRAX 50毫克/胶囊 100胶囊/盒
【中文参考药品译名】头孢克肟
【生产厂家中文参考译名】Fujisawa Toyama Co.,Ltd.
【生产厂家英文名】Fujisawa Toyama Co.,Ltd

Drug Information For: SUPRAX

Ingredient Name: CEFIXIME (sef-IX-eem)

Drug Manufacturer: LUPIN PHARMACEUTICALS

Common Uses: This medicine is a cephalosporin antibiotic used for treating infections caused by certain bacteria.

Before Using This Medicine: Some medicines or medical conditions may interact with this medicine. INFORM YOUR DOCTOR OR PHARMACIST of all prescription and over-the-counter medicine that you are taking. DO NOT TAKE THIS MEDICINE IF you will be having a live typhoid vaccine. ADDITIONAL MONITORING OF YOUR DOSE OR CONDITION may be needed if you are taking anticoagulants (eg, warfarin) or carbamazepine. DO NOT START OR STOP any medicine without doctor or pharmacist approval. Inform your doctor of any other medical conditions, including diarrhea, stomach or bowel problems (eg, inflammation), bleeding or blood clotting problems, liver problems, poor nutrition, allergies, pregnancy, or breast-feeding. Tell your doctor if you have a history of kidney problems or you are on dialysis treatment. Contact your doctor or pharmacist if you have any questions or concerns about using this medicine.

How to Use This Medicine: Follow the directions for taking this medicine provided by your doctor. Take this medicine by mouth with or without food. If stomach upset occurs, take with food to reduce stomach irritation. SHAKE WELL before each use. USE A MEASURING DEVICE marked for medicine dosing. Ask your pharmacist for help if you are unsure of how to measure your dose. STORE THIS MEDICINE at room temperature, between 68 and 77 degrees F (20 and 25 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. This medicine may also be stored in the refrigerator between 36 and 46 degrees F (2 and 8 degrees C). Do not freeze. Throw away any unused medicine after 14 days. TO CLEAR UP YOUR INFECTION COMPLETELY, continue using this medicine for the full course of treatment even if you feel better in a few days. IF YOU MISS A DOSE OF THIS MEDICINE, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Cautions: DO NOT USE THIS MEDICINE IF you are allergic to any ingredient in this medicine or to other cephalosporins (eg, cephalexin). Tell your doctor if you have had a severe allergic reaction to a penicillin (eg, amoxicillin) or another beta-lactam antibiotic (eg, imipenem). If you have a question about whether you are allergic to this medicine or if a certain medicine is a penicillin or beta-lactam antibiotic, contact your doctor or pharmacist. THIS MEDICINE MAY INTERFERE WITH certain lab tests. Be sure your doctor and lab personnel know you are using this medicine. THIS MEDICINE MAY CAUSE DIZZINESS. This effect may be worse if you take it with alcohol or certain medicines. Use this medicine with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it. DO NOT CHANGE DOSE FORMS (eg, tablets, suspension) of this medicine without talking with your doctor. MILD DIARRHEA IS COMMON WITH ANTIBIOTIC USE. However, a more serious form of diarrhea (pseudomembranous colitis) may rarely occur. This may develop while you use the antibiotic or within several months after you stop using it. Contact your doctor right away if stomach pain or cramps, severe diarrhea, or bloody stools occur. Do not treat diarrhea without first checking with your doctor. THIS MEDICINE ONLY WORKS AGAINST BACTERIA; it does not treat viral infections (eg, the common cold). BE SURE TO USE THIS MEDICINE for the full course of treatment. If you do not, the medicine may not clear up your infection completely. The bacteria could also become less sensitive to this or other medicines. This could make the infection harder to treat in the future. LONG-TERM OR REPEATED USE OF THIS MEDICINE may cause a second infection. Tell your doctor if signs of a second infection occur. Your medicine may need to be changed to treat this. THIS MEDICINE MAY REDUCE the number of clot-forming cells (platelets) in your blood. Avoid activities that may cause bruising or injury. Tell your doctor if you have unusual bruising or bleeding. Tell your doctor if you have dark, tarry, or bloody stools. DO NOT RECEIVE a live typhoid vaccine while you are taking this medicine. It may not work as well. Talk with your doctor if you are scheduled to receive a live typhoid vaccine. BEFORE YOU BEGIN TAKING ANY NEW MEDICINES, either prescription or over-the-counter, check with your doctor or pharmacist. FOR WOMEN: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using this medicine while you are pregnant. It is not known if this medicine is found in breast milk. If you are or will be breast-feeding while you use this medicine, check with your doctor or pharmacist. Discuss any possible risks to your baby. DIABETES PATIENTS - This medicine may cause the results of some tests for urine glucose or urine ketones to be wrong. Ask your doctor before you change your diet or the dose of your diabetes medicine.

Possible Side Effects: SIDE EFFECTS that may occur while taking this medicine include diarrhea; gas; loose stools; nausea; or stomach pain or upset. If they continue or are bothersome, check with your doctor. CONTACT YOUR DOCTOR IMMEDIATELY if you experience bloody stools; decreased urination; fever, chills, or sore throat; red, swollen, blistered, or peeling skin; seizures; severe diarrhea; severe nausea or vomiting; severe stomach pain or cramping; unusual bruising or bleeding; vaginal discharge or itching; white spots in the mouth; or yellowing of the skin or eyes. AN ALLERGIC REACTION to this medicine is unlikely, but seek immediate medical attention if it occurs. Symptoms of an allergic reaction include rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue; or unusual hoarseness. If you notice other effects not listed above, contact your doctor, nurse, or pharmacist. This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your healthcare provider. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Overdose: IF OVERDOSE IS SUSPECTED, contact your local poison control center or emergency room immediately.

Additional Information: If your symptoms do not improve or if they get worse, check with your doctor. DO NOT SHARE THIS MEDICINE with others for whom it was not prescribed. DO NOT USE THIS MEDICINE for other health conditions. KEEP THIS MEDICINE out of the reach of children and pets.