【通用名称】AVINZA 【剂　　型】CAPSULE, EXTENDED RELEASE; ORAL 【规　　格】90MG 【活性成份】MORPHINE SULFATE【注意】强调该产品不能与酒精和含酒精成份的药品一起使用。 患者不要将本品与酒精饮料同时服用；在治疗期间也不能与含酒精的处方药或非处方药同时使用；和酒精同时服用可能导致吗啡快速释放并达到潜在致命的剂量。 【临床药理】当Avinza 30 mg与900 mL 含乙醇的缓冲溶液（20% 和 40%）混合，吗啡释放的剂量与酒精的浓度相关，可导致吗啡释放加速。尽管吗啡的体外试验结果与在体内处置的相关性还需要进一步确定，但在体外的这种加速释放可能与吗啡在体内释放类似，从而达到潜在致命的剂量并被人体吸收。 【原产地英文商品名】AVINZA-120mg/Capsule,100Capsules,Sustained Release 24 Hr 【原产地英文药品名】MORPHINE SULFATE 【中文参考商品译名】 注：以下产品不同规格和不同价格，购买时请以电话咨询为准！ ·阿万择-30毫克/胶囊，100胶囊/瓶，24小时缓释 ·阿万择-60毫克/胶囊，100胶囊/瓶，24小时缓释 ·阿万择-90毫克/胶囊，100胶囊/瓶，24小时缓释 ·阿万择-120毫克/胶囊，100胶囊/瓶，24小时缓释 【中文参考药品译名】硫酸吗啡 【生产厂家英文名】Ligand AVINZA® is indicated as a once-daily morphine treatment for chronic moderate-to-severe pain in patients who require continuous, around-the-clock opioid therapy for an extended period of time. AVINZA® (morphine sulfate extended-release capsules) is a prescription drug that contains morphine. Each AVINZA® Capsule contains enough morphine to last for 24 hours and should be taken once a day. AVINZA® is for adults 18 years or older with moderate to severe pain who need around-the-clock, nonstop treatment for an extended period of time. AVINZA® Capsules are to be swallowed whole. DO NOT chew, crush, or dissolve the beads in capsules before swallowing. If the beads are chewed, crushed, or dissolved, the entire 24-hour dose may be absorbed into your body all at once. This can lead to serious problems, including overdose and death If you have trouble swallowing the capsules, you may open them and sprinkle all of the beads on a small amount of applesauce just before swallowing. Make sure to swallow all of the beads whole Do not drink alcoholic beverages while using AVINZA®, or use prescription or nonprescription medications that contain alcohol. Consuming alcohol while taking AVINZA® may cause the rapid release and absorption of a potentially deadly dose of morphine Because AVINZA® may make you sleepy, you should not drive, operate heavy machinery, or perform any other possibly dangerous activities until you know how you react to AVINZA® AVINZA® should not be given to anyone other than the person for whom it was prescribed Tell your healthcare professional about the following: Any and all other health or medical problems you may have All medicines (prescription and nonprescription) and vitamins you are taking. Do not take other medicines without your healthcare professional’s approval If you are pregnant or plan to become pregnant If you are breastfeeding, because morphine will pass through the milk and may harm the baby If you have abused drugs in the past. There is a risk of abuse or addiction with all opioid medications. You may have a higher chance of developing an abuse problem or addiction again while using AVINZA® AVINZA® is not for everyone. Only you and your healthcare professional can know if AVINZA® is right for you. Make sure to follow your healthcare professional’s directions exactly. Do not change your dose unless your healthcare professional tells you to change it Do not take AVINZA® more often than prescribed. You should not stop taking AVINZA® all at once if you have been taking it for more than a few days. Your healthcare professional can instruct you on how to stop taking this medicine slowly to avoid uncomfortable symptoms Constipation is a common side effect of medicines that contain morphine, including AVINZA®. When you start taking AVINZA®, discuss steps to prevent or relieve constipation with your healthcare professional. Other common side effects of AVINZA® are nausea, drowsiness, headache, and itching. Some of these side effects may decrease with continued use.