【药物名称】雌二醇氮芥 Estramustine 【药物别名】癌腺治,依立适 Estracyt 【制剂规格】胶囊:每粒150mg。粉针剂:每支150mg;300mg。 【药理毒理】雌二醇氮芥是依据“受体学说”设计的药物,是以雌二醇磷酸酯为载体的氮芥类化合物,具有烷化剂和雌二醇的双重作用。根据“受体学说”、不同的专一性,甾体类激素对不同的靶器官具有不同的专一性。甾体类激素与烷化剂的结合物有可能选择性地进入激素依赖性的瘤组织中,从而减轻了烷化剂对全身的作用。这不仅发挥了甾体类激素的作用,而且也加强了烷化剂的抗癌效应,同时相应降低了烷化剂的毒副反应。 【适 应 证】前列腺癌、乳腺癌、胰腺癌,对其它晚期恶性肿瘤也有疗效。
【不良反应】 (1)轻度胃肠道反应,如恶心、呕吐等: (2)静脉给药可有暂时性骨髓抑制及血栓性静脉炎; (3)偶有肝功能异常; (4)罕见有乳腺肿胀、男性女性化。 【相互作用】 奶类制品会影响雌二醇氮芥的吸收。 【用法用量】静注:每日300~500mg溶于溶剂中静注,连用3周,然后改为每周2次;或改为口服;每日600~900mg,分2次。静脉或口服一般3~4周为1疗程,无效停用。 【注意事项】附带的粉针溶剂需小心缓慢地加入雌二醇氮芥的安瓶中,并避免震动,以防止起泡沫。等渗盐水不能作为溶剂使用。
Emcyt Drug Information Emcyt is a cancer medication that is used for treating metastatic or progressive prostate cancer. This generic medication is quite similar to other cancer medications. It also interferes with the growth of cancer cells and stops them from growing and spreading in your body. It affects the rapidly multiplying cancerous cells by altering the DNA or the RNA of these cells thus impacting their ability to multiply. Subsequently, this medication also helps in killing off the cancerous cells.
Emcyt Dosage Information The recommended dosage for treating prostate cancer is 14 mg / kg bodyweight to be taken in two or three doses. Buy Emcyt 140 mg from North Meds and experience the convenience of shopping for medicines from home. Get huge rebates on the purchase of discount Emcyt online.
Side Effects and Precautions for Emcyt Estramustine may cause serious side effects like nausea, sweating, chest pain or heaviness in the chest, pain spreading to the arm or the shoulder, sudden numbness or weakness, sudden headache and confusion, problems with vision, balance or speech, sudden cough, wheezing, chest pain, fast heart rate, easy bruising, rapid weight gain and pain or swelling in one or both legs. If you have any of these side effects get immediate medical treatment. Emcyt can also lead to less serious side effects like loss of appetite, nausea, upset stomach or diarrhea, feeling weak or tired, impotence and tenderness or swelling of breasts. If these side effects persist consult your doctor for further advice.
Do not use this medication if you are allergic to Estramustine. Tell your doctor if you have a history of blood clots, heart attack or stroke, high blood pressure, diabetes, coronary artery disease, migraine headaches, liver or kidney disease, congestive heart failure or a metabolic bone disease. While taking this medication you father a child it may have birth defects. Always use a condom to prevent pregnancy when on this drug. Also discuss with your doctor whether using cheap Emcyt is alright or not. |