中文名：愈创甘油醚

中文化学名：3-(2-甲氧基苯氧基)丙烷-1,2-二醇 　　

英文化学名：3-(2-Methoxyphenoxy)-1,2-propanediol

适应症：祛痰

功用作用：口服后刺激胃黏膜，反射性引起支气管分泌增加，使痰液稀释。并有消毒防腐作用，本品还具有镇咳、解痉、抗惊厥作用，用于慢性支气管炎的多痰咳嗽、肺脓肿、支气管扩张和继发性哮喘。多与其他镇咳平喘药合用。用于黏液不易咳出的情况。愈创甘油醚为祛痰剂，能刺激胃黏膜反射性引起支气管黏膜腺体分泌增加，降低痰的黏性，使黏痰易于咳出。  　　

用法用量：口服。片剂，成人一次0.1～0.2克，一日3～4次；儿童每公斤体重一次15毫克，6小时1次。糖浆剂一次10～15毫升，一日3次。 　　

不良反应：可见恶心、胃肠不适、头晕、嗜睡和过敏等。 

注意事项：
1.消化道溃疡患者慎用。
2.孕妇及哺乳期妇女慎用。
3.本品应饭后服用。
4.儿童必须在成人监护下使用。
5.当本品性状发生改变时禁用。
6.请将此药品放在儿童不能接触的地方。
 
禁忌症：
1.对本品过敏者禁用。
2.急性胃肠炎、肾炎和肺出血患者禁用。
 
其它说明：如正在服用其他药品，在使用本品前请咨询医师或药师。 

愈创甘油醚作为祛痰剂的使用历史已经相当长，并已被收载入英国、美国等国药典。美国愈创甘油醚总市场约为11亿美元，在我国，愈创甘油醚被列入第一批非处方药目录。 
阿当斯公司致力于变态反应用药和呼吸系统用药的研发和销售，2002年7月15日该公司宣布，愈创甘油醚长效制剂Mucinex作为非处方药上市的申请已获得FDA 批准。Mucinex规格为600mg／片，每12小时服两片。 Mucinex运用双层药物传输系统技术：第一层可将药物迅速释放到血液以缓解突发症状；第二层为缓释系统，可维持12小时药效。 
Adams公司是一家呼吸系统药物的供应商，该公司宣布FDA已经批准了两种浓度的Mucinex®DM（缓释呱芬那辛guaifenesin600mg/氢溴酸右美沙芬dextromethorphanHBr30mg和呱芬那辛guaifenesin1200mg/氢溴酸右美沙芬dextromethorphanHBr60mg）。Mucinex®DM是一种化痰剂和止咳剂，从2004年9月起患者将无需处方就可以在全国所有的药品零售柜台买到。
    Mucinex®DM是FDA批准的第一个呱芬那辛guaifenesin和氢溴酸右美沙芬dextromethorphanHBr的复方缓释药物。这类产品之前只能作为处方药获得。在2002年6月，Adams公司的药物Mucinex®（缓释呱芬那辛guaifenesin600/1200mg）已经获得了FDA的批准.

Mucinex Oral
Mucinex Oral Uses
This medication is used for the temporary relief of coughs caused by the common cold, bronchitis, and other breathing illnesses. This product is usually not used for ongoing cough from smoking or long-term breathing problems (such as chronic bronchitis, emphysema) unless directed by your doctor. Guaifenesin is an expectorant. It works by thinning and loosening mucus in the airways, clearing congestion, and making breathing easier.

If you are self-treating with this medication, it is important to read the package instructions carefully before you start using this product to be sure it is right for you. (See also Precautions section.)

Cough-and-cold products have not been shown to be safe or effective in children younger than 6 years. This product (sustained-release) is not recommended for use in children younger than 12 years unless specifically directed by the doctor. Ask your doctor or pharmacist for more details about using your product safely.

These products do not cure or shorten the length of the common cold. To decrease the risk for side effects, carefully follow all dosage directions. Do not give other cough-and-cold medication that might contain the same or similar ingredients (see also Drug Interactions section). Ask the doctor or pharmacist about other ways to relieve cough and cold symptoms (such as drinking enough fluids, using a humidifier or saline nose drops/spray).

How to use Mucinex Oral
Take this medication by mouth with or without food, as directed by your doctor, usually every 12 hours with a full glass of water. If you are self-treating, follow all directions on the product package. If you are uncertain about any of the information, ask your doctor or pharmacist.

Dosage is based on your age, medical condition, and response to treatment. Do not take more than 2400 milligrams in 24 hours. Do not increase your dose or take this drug more often than directed.

Do not crush or chew this medication. Doing so can release all of the drug at once, increasing the risk of side effects. Also, do not split the tablets unless they have a score line and your doctor or pharmacist tells you to do so. Swallow the whole or split tablet without crushing or chewing.

Drink plenty of fluids while taking this medication. Fluids will help to break up mucus and clear congestion.

Tell your doctor if your condition returns, or if it is accompanied by fever, severe sore throat, rash, persistent headache, or if it persists or worsens after 7 days. These may be signs of a serious medical problem. Seek immediate medical attention if you think you may have a serious medical problem.

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Mucinex Oral Side Effects
Nausea or vomiting may occur. If either of these effects persist or worsen, tell your doctor or pharmacist promptly.

If your doctor has directed you to use this medication, remember that he or she has judged that the benefit to you is greater than the risk of side effects. Most people using this medication do not have serious side effects.

A very serious allergic reaction to this drug is rare. However, seek immediate medical attention if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.

This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

In the US -Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

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Mucinex Oral Precautions
Before taking guaifenesin, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: breathing problems (such as emphysema, chronic bronchitis, asthma, smoker's cough), cough with blood or large amounts of mucus.

Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products).

During pregnancy, this medication should be used only when clearly needed. Discuss the risks and benefits with your doctor.

It is unknown if guaifenesin passes into breast milk. Discuss the risks and benefits with your doctor before breast-feeding.

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Mucinex Oral Interactions
The effects of some drugs can change if you take other drugs or herbal products at the same time. This can increase your risk for serious side effects or may cause your medications not to work correctly. These drug interactions are possible, but do not always occur. Your doctor or pharmacist can often prevent or manage interactions by changing how you use your medications or by close monitoring.

To help your doctor and pharmacist give you the best care, be sure to tell your doctor and pharmacist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products) before starting treatment with this product. While using this product, do not start, stop, or change the dosage of any other medicines you are using without your doctor's approval.

Guaifenesin is available in both prescription and nonprescription products. Check the labels of all your medications to make sure you are not taking more than one product containing guaifenesin.

This product can affect the results of certain lab tests (such as urine levels of certain acids). Make sure laboratory personnel and all your doctors know you use this drug.

Keep a list of all the products you use. Share the list with your doctor and pharmacist to reduce your risk for serious medication problems.

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Mucinex Oral Overdose
If overdose is suspected, contact a poison control center or emergency room immediately. US residents can call the US National Poison Hotline at 1-800-222-1222. Canada residents can call a provincial poison control center.

NOTES:
If your doctor prescribed this medication, do not share this medication with others.

Keep all regular medical and laboratory appointments.

This medication is for temporary use only. Do not take this medication for more than 7 days unless your doctor tells you to do so. Tell your doctor if your condition lasts longer than 7 days.

MISSED DOSE:
If you miss a dose, take it as soon as you remember. If it is near the time of the next dose, skip the missed dose and resume your usual dosing schedule. Do not double the dose to catch up.

STORAGE:
Store at room temperature between 68-77 degrees F (20-25 degrees C) away from light and moisture. Do not store in the bathroom. Keep all medicines away from children and pets.

Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company for more details about how to safely discard your product.

Information last revised July 2010 Copyright(c) 2010 First DataBank, Inc

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原产地英文商品名:
MUCINEX DM ER TABLET 12HOUR (1200/60)mg/tab 28tabs/box
原产地英文药品名:
GUAIFENESIN/DEXTROMETHORPHAN HBR
原产地英文化合物名称:
3-(2-Methoxyphenoxy)-1,2-propanediol
中文参考商品译名:
MUCINEX DM ER12小时缓释片 (1200/60)毫克/片 28片/盒
生产厂家中文参考译名:
利洁时
生产厂家英文名:
RECKITT BENCKISER

---------------------------------------------------------------
原产地英文商品名:
MUCINEX DM ER TABLET 12HOUR (1200/60)mg/tab 14tabs/box
原产地英文药品名:
GUAIFENESIN/DEXTROMETHORPHAN HBR
原产地英文化合物名称:
3-(2-Methoxyphenoxy)-1,2-propanediol
中文参考商品译名:
MUCINEX DM ER12小时缓释片 (1200/60)毫克/片 14片/盒
生产厂家中文参考译名:
利洁时
生产厂家英文名:
RECKITT BENCKISER

---------------------------------------------------------------
原产地英文商品名:
MUCINEX DM ER TABLET 12HOUR (600/30)mg/tab 40tabs/box
原产地英文药品名:
GUAIFENESIN/DEXTROMETHORPHAN HBR
原产地英文化合物名称:
3-(2-Methoxyphenoxy)-1,2-propanediol
中文参考商品译名:
MUCINEX DM ER12小时缓释片 (600/30)毫克/片 40片/盒
中文参考药品译名:
愈创甘油醚/氢溴酸右美沙芬
中文参考化合物名称:
3-(2-甲氧基苯氧基)丙烷-1,2-二醇
生产厂家中文参考译名:
利洁时
生产厂家英文名:
RECKITT BENCKISER

---------------------------------------------------------------
原产地英文商品名:
MUCINEX DM ER TABLET 12HOUR (600/30)mg/tab 20tabs/box
原产地英文药品名:
GUAIFENESIN/DEXTROMETHORPHAN HBR
原产地英文化合物名称:
3-(2-Methoxyphenoxy)-1,2-propanediol
中文参考商品译名:
MUCINEX DM ER12小时缓释片 (600/30)毫克/片 20片/盒
中文参考药品译名:
愈创甘油醚/氢溴酸右美沙芬
中文参考化合物名称:
3-(2-甲氧基苯氧基)丙烷-1,2-二醇
生产厂家中文参考译名:
利洁时
生产厂家英文名:
RECKITT BENCKISER

---------------------------------------------------------------
原产地英文商品名:
MUCINEX DM TABLET 12HOUR 14tabs/box
原产地英文药品名:
GUAIFENESIN/DEXTROMETHORPHAN HBR
原产地英文化合物名称:
3-(2-Methoxyphenoxy)-1,2-propanediol
中文参考商品译名:
MUCINEX DM12小时缓释片 14片/盒
中文参考药品译名:
愈创甘油醚/氢溴酸右美沙芬
中文参考化合物名称:
3-(2-甲氧基苯氧基)丙烷-1,2-二醇
生产厂家中文参考译名:
利洁时
生产厂家英文名:
RECKITT BENCKISER
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